Ecclesiastes

Ecclesiastes

Author: Troy A. Fritch Sr.

Publisher: AuthorHouse

Published: 2014-08-26

Total Pages: 314

ISBN-13: 1496935322

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Man has long since sought to become something in this existence called life. He seeks to leave a legacy of remembrance and great achievement behind for generations to follow. But through the Wisdom of Solomon, as given by The Almighty God of Creation, we are to learn that all mans efforts are futile and absolute worthlessness; if God has not been made the central part of your life.


When Doctors Say No

When Doctors Say No

Author: Susan B. Rubin

Publisher: Indiana University Press

Published: 1998-10-22

Total Pages: 214

ISBN-13: 9780253112965

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"The book is a fine addition to the world of academic medical ethics... Readers... will come away with some of the tools for further debate." -- Publishers Weekly "Susan B. Rubin's splendid new book... offers positive, humane solutions to the frustrations that have given rise to the futility debate." -- Carl Elliott, Medical Humanities Review "Rubin offers a thorough and thought-provoking exploration of the concept of futility as a basis for medical decisions." -- Choice "... [the] brilliant analysis found in Rubin's [book] couldn't be more timely.... When Doctors Say No is the most thorough philosophical rebuttal to be found in the literature of medical futility as the basis for unilateral decisionmaking by physicians." -- Charles Weijer, Canadian Medical Association Journal Should physicians be permitted to unilaterally refuse to provide treatment that they deem futile? Even if the patient, or the patient's family, insists that everything possible must be done? In this book, philosopher and bioethicist Rubin examines this controversial issue. She offers a critique of the concept of medical futility and the debate surrounding it, and she calls for more public debate about the underlying issues at stake for all of us -- patients, families, health care providers, insurers, and society at large.


Finding God at Harvard

Finding God at Harvard

Author: Kelly K. Monroe

Publisher: Zondervan

Published: 1997-09-18

Total Pages: 372

ISBN-13: 9780310219224

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Kelly Monroe presents forty-two compelling testimonies from faculty members, former students, and orators at Harvard University whose reflections explode the myth that Christian faith cannot survive a rigorous intellectual environment.


Clinical Trials in Neurology

Clinical Trials in Neurology

Author: Bernard Ravina

Publisher: Cambridge University Press

Published: 2012-04-12

Total Pages: 387

ISBN-13: 1107376572

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Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.


Combinatorics, Algorithms, Probabilistic and Experimental Methodologies

Combinatorics, Algorithms, Probabilistic and Experimental Methodologies

Author: Bo Chen

Publisher: Springer Science & Business Media

Published: 2007-09-28

Total Pages: 540

ISBN-13: 3540744495

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The First International Symposium on Combinatorics, Algorithms, Probabilistic and Experimental Methodologies was held in Hangzhou, China, in April 2007. The symposium provided an interdisciplinary forum for researchers to share their discoveries and approaches; search for ideas, methodologies, and tool boxes; find better, faster, and more accurate solutions; and develop a research agenda of common interest. This volume constitutes the refereed post-proceedings of the symposium. Inside you'll find 46 full papers. They represent some of the most important thinking and advancements in the field. The papers address large data processing problems using different methodologies from major disciplines such as computer science, combinatorics, and statistics.


Design for Living

Design for Living

Author: Robert Friedmann

Publisher: Wipf and Stock Publishers

Published: 2017-11-29

Total Pages: 201

ISBN-13: 1532632053

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Written in 1954 but unpublished in his lifetime, Robert Friedmann’s Design for Living asks that pertinent existential question: how should we live? Drawing on literary, philosophical, and theological sources, Friedmann’s answer begins with a critique of utilitarian ethics and popular apathy, and proceeds through an existential preparation that ascends in confessional style to the question of the meaning of human life, culminating in a fourfold set of principles: regard, concern, service, and love. Along the way, Friedmann’s critical eye remains clearly fixed on his object of study—lived experience, and not abstract principles detached from day-to-day life—and he intentionally guides his reader step by step up the mountain of spiritual and ethical inquiry in a deliberate and serious attempt to educate the heart, mind, and soul. At once accessible and scholarly, while troubling our contemporary divide between religion and the secular, Design for Living presents a rare vision of human meaning and purpose that will appeal to scholarly and public readers alike.


The Puzzled Preacher

The Puzzled Preacher

Author: David Balsley

Publisher: WestBow Press

Published: 2016-01-25

Total Pages: 338

ISBN-13: 1490896112

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Why did the Lord see fit to include the book of Ecclesiastes in His inspired Word? Down through the centuries, many people have wondered how Solomon could have moved so far from his walk with the Lord and the wisdom of the Proverbs to the pessimism of Ecclesiastes in one lifetime. For this reason, some have questioned Solomons authorship of the book. But Solomon is only one of many who have taken a spiritual detour in life. As a result, there are many people in our nation and our world who can readily identify with the outlook of Ecclesiastes, because they too are living their lives as Solomon did for a timeunder the sun. This verse-by-verse tour of Solomons experience will help you understand where Solomons spiritual detour took him, and where he finally came to realize he should have been going instead. You will be encouraged to move out from under the sun to the abundance of life in the light of the Son!


Planning and Analyzing Clinical Trials with Composite Endpoints

Planning and Analyzing Clinical Trials with Composite Endpoints

Author: Geraldine Rauch

Publisher: Springer

Published: 2018-05-22

Total Pages: 254

ISBN-13: 3319737708

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This book addresses the most important aspects of how to plan and evaluate clinical trials with a composite primary endpoint to guarantee a clinically meaningful and valid interpretation of the results. Composite endpoints are often used as primary efficacy variables for clinical trials, particularly in the fields of oncology and cardiology. These endpoints combine several variables of interest within a single composite measure, and as a result, all variables that are of major clinical relevance can be considered in the primary analysis without the need to adjust for multiplicity. Moreover, composite endpoints are intended to increase the size of the expected effects thus making clinical trials more powerful. The book offers practical advice for statisticians and medical experts involved in the planning and analysis of clinical trials. For readers who are mainly interested in the application of the methods, all the approaches are illustrated with real-world clinical trial examples, and the software codes required for fast and easy implementation are provided. The book also discusses all the methods in the context of relevant guidelines related to the topic. To benefit most from the book, readers should be familiar with the principles of clinical trials and basic statistical methods.


Textbook of Clinical Trials in Oncology

Textbook of Clinical Trials in Oncology

Author: Susan Halabi

Publisher: CRC Press

Published: 2019-04-24

Total Pages: 708

ISBN-13: 1351620967

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There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for statisticians and investigators with minimal clinical trial experience who are interested in pursuing a career in this area. The advancement in genetic and molecular technologies have revolutionized drug development. In recent years, clinical trials have become increasingly sophisticated as they incorporate genomic studies, and efficient designs (such as basket and umbrella trials) have permeated the field. This book offers the requisite background and expert guidance for the innovative statistical design and analysis of clinical trials in oncology. Key Features: Cutting-edge topics with appropriate technical background Built around case studies which give the work a "hands-on" approach Real examples of flaws in previously reported clinical trials and how to avoid them Access to statistical code on the book’s website Chapters written by internationally recognized statisticians from academia and pharmaceutical companies Carefully edited to ensure consistency in style, level, and approach Topics covered include innovating phase I and II designs, trials in immune-oncology and rare diseases, among many others