Alternative Splicing in the Postgenomic Era
Alternative Splicing in the Postgenomic Era

Author: Benjamin J. Blencowe

Publisher: Springer Science & Business Media

Published: 2008-01-23

Total Pages: 260

ISBN-13: 9780387773735

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Yet again Springer has reached the market before everyone. This is the first book that is solely dedicated to the topic of alternative splicing. The book contains chapters by experts in the field that cover nearly all aspects of this hugely important subject. The purpose of the text is to provide a single, authoritative source of information on alternative splicing that is accessible to researchers in diverse fields. It is suitable for beginners and experts alike.

Postgenomics
Postgenomics

Author: Sarah S. Richardson

Publisher: Duke University Press

Published: 2015-05-29

Total Pages: 286

ISBN-13: 0822375443

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Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens

RNA Splicing and Backsplicing: Disease and Therapy
RNA Splicing and Backsplicing: Disease and Therapy

Author: Rosanna Asselta

Publisher: Frontiers Media SA

Published: 2020-12-24

Total Pages: 197

ISBN-13: 2889662357

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Post-Transcriptional Gene Regulation
Post-Transcriptional Gene Regulation

Author: Jane Wu

Publisher: John Wiley & Sons

Published: 2013-04-24

Total Pages: 400

ISBN-13: 3527665412

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Reflecting the rapid progress in the field, the book presents the current understanding of molecular mechanisms of post-transcriptional gene regulation thereby focusing on RNA processing mechanisms in eucaryotic cells. With chapters on mechanisms as RNA splicing, RNA interference, MicroRNAs, RNA editing and others, the book also discusses the critical role of RNA processing for the pathogenesis of a wide range of human diseases. The interdisciplinary importance of the topic makes the title a useful resource for a wide reader group in science, clinics as well as pharmaceutical industry.

Biological and Medical Data Analysis
Biological and Medical Data Analysis

Author: Nicos Maglaveras

Publisher: Springer

Published: 2006-11-23

Total Pages: 507

ISBN-13: 3540680659

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This book constitutes the refereed proceedings of the 7th International Symposium on Biological and Medical Data Analysis, ISBMDA 2006, held in Thessaloniki, Greece, December 2006. Coverage in this volume includes functional genomics, sequence analysis, biomedical models, information modeling, biomedical signal processing, biomedical image analysis, biomedical data analysis, as well as decision support systems and diagnostic tools.

Linkage in Evolutionary Computation
Linkage in Evolutionary Computation

Author: Ying-ping Chen

Publisher: Springer Science & Business Media

Published: 2008-09-26

Total Pages: 487

ISBN-13: 3540850678

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In recent years, the issue of linkage in GEAs has garnered greater attention and recognition from researchers. Conventional approaches that rely much on ad hoc tweaking of parameters to control the search by balancing the level of exploitation and exploration are grossly inadequate. As shown in the work reported here, such parameters tweaking based approaches have their limits; they can be easily ”fooled” by cases of triviality or peculiarity of the class of problems that the algorithms are designed to handle. Furthermore, these approaches are usually blind to the interactions between the decision variables, thereby disrupting the partial solutions that are being built up along the way.

Bioinformatics Research and Applications
Bioinformatics Research and Applications

Author: Ion Mandoiu

Publisher: Springer

Published: 2009-04-29

Total Pages: 350

ISBN-13: 3642015514

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This book constitutes the refereed proceedings of the 5th International Symposium on Bioinformatics Research and Applications, ISBRA 2009, held in Fort Lauderdale, FL, USA, in May 2009. The 26 revised full papers presented together four invited papers were carefully reviewed and selected from a total of 55 submissions. The papers cover a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

Handbook of Neurotoxicity
Handbook of Neurotoxicity

Author: Richard M. Kostrzewa

Publisher: Springer Nature

Published: 2023-01-02

Total Pages: 2551

ISBN-13: 3031150805

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This handbook is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. This new edition significantly expands on the information provided in the first edition, providing the latest research in neurotoxicity and highlighting the relationship between specific neurotoxins and the neurodegenerative disorders they can cause. It also includes new sections on the neurotoxicity of heavy metals, fungi, and snake venom. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.