Alternative Radionuclide Production with a Cyclotron
Alternative Radionuclide Production with a Cyclotron

Author: IAEA

Publisher: International Atomic Energy Agency

Published: 2021-10-01

Total Pages: 102

ISBN-13: 9201032218

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Cyclotrons are currently used for the preparation of a wide variety of radionuclides that have applications in single photon emission computed tomography (SPECT) and positron emission tomography (PET). Consequently, there is high demand from IAEA Member States for support in the area of radiopharmaceutical production using cyclotron produced radioisotopes. This publication describes the potential radionuclide production routes using cyclotrons in different energy ranges and provides methods for the development of targets and provides details of the chemistry for the separation of radionuclides from target materials. The readership of this publication includes scientists, operators interested in putting this technology into practice, technologists already working with cyclotrons who wish to enhance the utility of existing machines, and managers in the process of setting up radionuclide facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.

Cyclotron Produced Radionuclides
Cyclotron Produced Radionuclides

Author:

Publisher:

Published: 2008

Total Pages: 0

ISBN-13: 9789201002082

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This book provides a comprehensive treatment of cyclotrons, with a special emphasis on production of radionuclides. Individual sections are devoted to accelerator technology, theoretical aspects of nuclear reactions, the technology behind targetry, techniques for preparation of targets, irradiation of targets under high beam currents, target processing and target recovery. This book will appeal to scientists and technologists interested in translating cyclotron technology into practice, as well as postgraduate students in this field.

Medical Radionuclide Production
Medical Radionuclide Production

Author: Syed M. Qaim

Publisher: de Gruyter

Published: 2019

Total Pages: 0

ISBN-13: 9783110601565

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The work describes the production technology of standard medical radionuclides using reactors and cyclotrons for patient diagnosis and therapy. A special focus lies on the science and technology involved in the development of novel radionuclides for positron emission tomography (PET) and internal targeted radiotherapy. The availability of those radionuclides is opening up new potential in clinical research, especially in neurology, cardiology and oncology. The future perspectives of the developing technology are also discussed.

Cyclotron Produced Radionuclides
Cyclotron Produced Radionuclides

Author: International Atomic Energy Agency

Publisher:

Published: 2009

Total Pages: 266

ISBN-13: 9789201069085

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Application of radioisotopes has shown significant growth in the past decade, and a major factor contributing towards this growth is the availability of a large number of cyclotrons dedicated to the production of radioisotopes for medical applications. Although there are many articles in journals on cyclotrons and their use for radioisotope production, there is no single source of information for beginners on radioisotope production using cyclotrons. This publication attempts to address this deficiency. Its contains chapters on accelerator technology, theoretical considerations of nuclear reactions, the technology behind targetry, techniques on preparation of targets, irradiation of targets under high beam currents, target processing and target recovery.

Cyclotron Based Production of Technetium-99m
Cyclotron Based Production of Technetium-99m

Author: International Atomic Energy Agency

Publisher:

Published: 2017

Total Pages: 0

ISBN-13: 9789201029164

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This publication presents a comprehensive overview of the technologies involved in the production of cyclotron based 99mTc. These would include techniques relevant to preparation of targets, irradiation of targets under high beam currents, target processing, target recovery and quality control of the final product. The publication provides broad information, well supported with references, on improved production routes and improved separation and purification of cyclotron based 99mTc. These approaches achieve high specific activity and chemical purity of 99mTc suitable for labelling molecules of medical interest and also enable spare capacity to be available at medical cyclotron centres. The readership of this publication is scientists interested in translating this technology to practice, technologists already working with cyclotrons wanting to enhance the utility of the existing machines and managers who are in the process of setting up facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.

An Introduction to the Physics of Nuclear Medicine
An Introduction to the Physics of Nuclear Medicine

Author: Laura Harkness-Brennan

Publisher: Morgan & Claypool Publishers

Published: 2018-06-27

Total Pages: 95

ISBN-13: 1643270346

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The complexity and vulnerability of the human body has driven the development of a diverse range of diagnostic and therapeutic techniques in modern medicine. The Nuclear Medicine procedures of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and Radionuclide Therapy are well-established in clinical practice and are founded upon the principles of radiation physics. This book will offer an insight into the physics of nuclear medicine by explaining the principles of radioactivity, how radionuclides are produced and administered as radiopharmaceuticals to the body and how radiation can be detected and used to produce images for diagnosis. The treatment of diseases such as thyroid cancer, hyperthyroidism and lymphoma by radionuclide therapy will also be explored.

Cyclotron Produced Radionuclides
Cyclotron Produced Radionuclides

Author:

Publisher: Technical Reports Series

Published: 2009

Total Pages: 0

ISBN-13: 9789201031099

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Cyclotrons are used for preparation of a wide variety of radionuclides that find application in single photon emission computed tomography (SPECT) as well as in positron emission tomography (PET). This publication gives comprehensive guidelines for the planning and decision making processes and design and implementation of a cyclotron based radionuclide production facility. It will enable Member States to plan such facilities in a cost effective manner.

Radiation Safety of Accelerator Based Radioisotope Production Facilities
Radiation Safety of Accelerator Based Radioisotope Production Facilities

Author: IAEA

Publisher: International Atomic Energy Agency

Published: 2020-08-18

Total Pages: 102

ISBN-13: 9201057229

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Radioisotopes are used worldwide in a range of medical, industrial, research and academic applications. A large proportion of these radioisotopes are produced in particle accelerators, and the number of institutions that operate linear accelerators or cyclotrons and manufacture and distribute radiopharmaceuticals, for example, is significant and increasing. The production of radioisotopes using particle accelerators poses significant radiation hazards to workers, members of the public, and the environment when accelerators are operated without adequate radiation safety measures. This Safety Guide provides practical guidance for implementing radiation protection and safety measures in such facilities involved in the production and use of radioisotopes.

Isotopes for Medicine and the Life Sciences
Isotopes for Medicine and the Life Sciences

Author: Institute of Medicine

Publisher: National Academies Press

Published: 1995-01-27

Total Pages: 144

ISBN-13: 0309176697

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Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Handbook of Radiopharmaceuticals
Handbook of Radiopharmaceuticals

Author: Michael J. Welch

Publisher: John Wiley & Sons

Published: 2003-01-17

Total Pages: 872

ISBN-13: 9780471495604

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A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States