Allostasis, Homeostasis, and the Costs of Physiological Adaptation

Allostasis, Homeostasis, and the Costs of Physiological Adaptation

Author: Jay Schulkin

Publisher: Cambridge University Press

Published: 2004-10-25

Total Pages: 388

ISBN-13: 9780521811415

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The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.


Active Inference

Active Inference

Author: Thomas Parr

Publisher: MIT Press

Published: 2022-03-29

Total Pages: 313

ISBN-13: 0262362287

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The first comprehensive treatment of active inference, an integrative perspective on brain, cognition, and behavior used across multiple disciplines. Active inference is a way of understanding sentient behavior—a theory that characterizes perception, planning, and action in terms of probabilistic inference. Developed by theoretical neuroscientist Karl Friston over years of groundbreaking research, active inference provides an integrated perspective on brain, cognition, and behavior that is increasingly used across multiple disciplines including neuroscience, psychology, and philosophy. Active inference puts the action into perception. This book offers the first comprehensive treatment of active inference, covering theory, applications, and cognitive domains. Active inference is a “first principles” approach to understanding behavior and the brain, framed in terms of a single imperative to minimize free energy. The book emphasizes the implications of the free energy principle for understanding how the brain works. It first introduces active inference both conceptually and formally, contextualizing it within current theories of cognition. It then provides specific examples of computational models that use active inference to explain such cognitive phenomena as perception, attention, memory, and planning.


Adaptation and Well-being

Adaptation and Well-being

Author: Jay Schulkin

Publisher:

Published: 2011

Total Pages: 204

ISBN-13: 9781107215573

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"Recently, an interest in our understanding of well-being within the context of competition and cooperation has re-emerged within the biological and neural sciences. Given that we are social animals, our well-being is tightly linked to interactions with others. Pro-social behavior establishes and sustains human contact, contributing to well-being. Adaptation and Well-Being is about the evolution and biological importance of social contact. Social sensibility is an essential feature of our central nervous systems, and what have evolved are elaborate behavioral ways in which to sustain and maintain the physiological and endocrine systems that underlie behavioral adaptations. Writing for his fellow academics, and with chapters on evolutionary aspects, chemical messengers and social neuroendocrinology among others, Jay Schulkin explores this fascinating field of behavioral neuroscience"--


Human Bonding

Human Bonding

Author: Cindy Hazan

Publisher: Guilford Press

Published: 2013-06-25

Total Pages: 410

ISBN-13: 1462510671

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This tightly edited volume provides an integrative overview of human bonding from infancy through adulthood. Through an attachment lens, the book synthesizes classic and cutting-edge research on close relationships and their profound impact in everyday life. Topics include infant - caregiver attachment, human social nature, child and adolescent social development, mate selection, love and sexual desire, hooking up and online dating, keys to relationship success, predictors and consequences of relationship dissolution, and the role of social connectedness in psychological adjustment and physical health. Readers get a complete introduction to the concepts, theories, and methods that define contemporary relationship science.˜


Systemic Homeostasis and Poikilostasis in Sleep

Systemic Homeostasis and Poikilostasis in Sleep

Author: Pier Luigi Parmeggiani

Publisher: World Scientific

Published: 2011

Total Pages: 138

ISBN-13: 1848165722

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This book aims at presenting biologists and clinicians with a compact description of the physiological manifestations of sleep that are significant from the viewpoint of the principle of homeostasis. In the jargon of the physiological literature, the word ?homeostasis?, introduced by W.B. Cannon (1926), refers to the existence of a constant state of extracellular body fluids with regard to their physical and chemical properties. Since normal cell function depends on the constancy of such fluids, in multicellular animals there are many regulatory mechanisms under the control of the central nervous system that act to maintain the constancy of the internal environment.The experimental study of homeostasis in wakefulness already revealed the nature and complexity of the underlying physiological mechanisms. Many of these regulatory mechanisms trigger compensatory changes according to the principle of negative feedback. In contrast, the control of homeostasis across sleep states is still an issue under debate concerning its physiological persistence and significance. The author's aim is to find the specific mechanistic proofs of the actual consistency or inconsistency of the principle in different states of sleep. In this respect, there are several interacting physiological functions that ought to be examined across the sleep states. The selection of the most significant experimental data is carried out with a view to present a simple but not simplistic approach to the issue.The book brings forth the evidence that the systemic homeostatic regulation of many physiological variables underlying cellular life is not active in a particular state of the ultradian sleep cycle in mammals. It also shows the theoretical and functional importance of the principle of homeostasis, as a criterion of the systemic characterisation of the integrative control of physiological functions by the central nervous system during sleep in mammals.


Rheostasis

Rheostasis

Author: Nicholas Mrosovsky

Publisher: New York : Oxford University Press

Published: 1990

Total Pages: 200

ISBN-13:

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This work offers a comprehensive re-examination and elaboration of homeostasis, a guiding principle in physiology that has received surprisingly little critical evaluation. Among the key topics addressed are questions concerning the competing demands of different regulatory systems within the body and the problem of maintaining equilibrium in such circumstances. The author makes the important point that the body does not always seek constancy of its internal environment, nor does it always react in ways that prevent change. On the contrary, sometimes physiological mechanisms actively promote change. These changes in regulated levels--termed "rheostasis"--are seen as having an adaptive value beyond a simple failure of homeostasis. This book compares and categorizes examples of rheostasis for a variety of physiological variables, and presents what is known about conflicts between different regulatory systems and their role in promoting the occurrence of rheostasis. Among other topics covered are weight loss during hibernation, calcium storage and reproduction, fever, and rates of fat deposition in adults. The work of an outstanding scholar, this integrative study represents a refreshing and essential new approach to one of the basic concepts in physiological science.


A Concise Guide to Understanding Suicide

A Concise Guide to Understanding Suicide

Author: Stephen H. Koslow

Publisher: Cambridge University Press

Published: 2014-09-18

Total Pages: 409

ISBN-13: 1107033233

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A concise review of current research into suicide providing a guide to understanding this disease and its increasing incidence globally.


Stress: Concepts, Cognition, Emotion, and Behavior

Stress: Concepts, Cognition, Emotion, and Behavior

Author: George Fink

Publisher: Academic Press

Published: 2016-03-10

Total Pages: 503

ISBN-13: 0128011378

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Stress: Concepts, Cognition, Emotion, and Behavior: Handbook in Stress Series, Volume 1, examines stress and its management in the workplace and is targeted at scientific and clinical researchers in biomedicine, psychology, and some aspects of the social sciences. The audience is appropriate faculty and graduate and undergraduate students interested in stress and its consequences. The format allows access to specific self-contained stress subsections without the need to purchase the whole nine volume Stress handbook series. This makes the publication much more affordable than the previously published four volume Encyclopedia of Stress (Elsevier 2007) in which stress subsections were arranged alphabetically and therefore required purchase of the whole work. This feature will be of special significance for individual scientists and clinicians, as well as laboratories. In this first volume of the series, the primary focus will be on general stress concepts as well as the areas of cognition, emotion, and behavior. - Offers chapters with impressive scope, covering topics including the interactions between stress, cognition, emotion and behaviour - Features articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field - Includes rich illustrations with explanatory figures and tables - Includes boxed call out sections that serve to explain key concepts and methods - Allows access to specific self-contained stress subsections without the need to purchase the whole nine volume Stress handbook series


Handbook of Behavioral Medicine

Handbook of Behavioral Medicine

Author: Andrew Steptoe

Publisher: Springer Science & Business Media

Published: 2010-09-27

Total Pages: 1054

ISBN-13: 0387094881

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Behavioral medicine emerged in the 1970s as the interdisciplinary field concerned with the integration of behavioral, psychosocial, and biomedical science knowledge relevant to the understanding of health and illness, and the application of this knowledge to prevention, diagnosis, treatment, and rehabilitation. Recent years have witnessed an enormous diversification of behavioral medicine, with new sciences (such as genetics, life course epidemiology) and new technologies (such as neuroimaging) coming into play. This book brings together such new developments by providing an up-to-date compendium of methods and applications drawn from the broad range of behavioral medicine research and practice. The book is divided into 10 sections that address key fields in behavioral medicine. Each section begins with one or two methodological or conceptual chapters, followed by contributions that address substantive topics within that field. Major health problems such as cardiovascular disease, cancer, HIV/AIDs, and obesity are explored from multiple perspectives. The aim is to present behavioral medicine as an integrative discipline, involving diverse methodologies and paradigms that converge on health and well being.


Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Author: National Research Council

Publisher: National Academies Press

Published: 2003-08-22

Total Pages: 223

ISBN-13: 030916785X

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Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.