A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
For fans of David Sedaris and Nora Ephron, a humorous, irreverent, and poignant look at the gifts, stereotypes, and inevitable challenges of aging, based on award-winning journalist Steven Petrow's wildly popular New York Times essay, "Things I'll Do Differently When I Get Old." Soon after his 50th birthday, Petrow began assembling a list of “things I won’t do when I get old”—mostly a catalog of all the things he thought his then 70-something year old parents were doing wrong. That list, which included “You won’t have to shout at me that I’m deaf,” and “I won’t blame the family dog for my incontinence,” became the basis of this rousing collection of do’s and don’ts, wills and won’ts that is equal parts hilarious, honest, and practical. The fact is, we don’t want to age the way previous generations did. “Old people” hoard. They bore relatives—and strangers alike—with tales of their aches and pains. They insist on driving long after they’ve become a danger to others (and themselves). They eat dinner at 4pm. They swear they don’t need a cane or walker (and guess what happens next). They never, ever apologize. But there is another way... In Stupid Things I Won’t Do When I Get Old, Petrow candidly addresses the fears, frustrations, and stereotypes that accompany aging. He offers a blueprint for the new old age, and an understanding that aging and illness are not the same. As he writes, “I meant the list to serve as a pointed reminder—to me—to make different choices when I eventually cross the threshold to ‘old.’” Getting older is a privilege. This essential guide reveals how to do it with grace, wisdom, humor, and hope. And without hoarding. Praise for Stupid Things I Won't Do When I Get Old: “Unbelievably witty and relatable, I alternated bursting into laughter and placing my hand over my face in horror thinking, Oh my God, is that me? I often say, at this age we have something young people can never have…wisdom. My dear friend, Steven Petrow, has wisdom to share in this honest, funny, wry guide to keep us young at heart, without desperately hanging onto our youth. I am buying this book for all of my friends!” —Suzanne Somers, New York Times bestselling author of A New Way to Age “Stupid Things I Won’t Do When I Get Old is an irreverent, funny, honest look at aging and all the things we take for granted as normal parts of aging. They don’t need to be. If you struggle with getting older and want to find a fresh perspective on lessons learned about what NOT to do as we age, and what TO do to stay young in heart, spirit, mind and body, read this book.” —Mark Hyman, MD, #1 New York Times bestseller author of The Blood Sugar Solution 10-Day Detox Diet, and Head of Strategy and Innovation at the Cleveland Clinic Center for Functional Medicine. “Steven Petrow resolved to do things differently than his parents had when he gets old because he wished they’d been able to enjoy life more. His solution? He created a list! In this book, he shares the secrets to living a full life regardless of our age. It's all about the decisions we make every day. My advice in a nutshell: Read this book and keep it handy.” —“Dear Abby” (Jeanne Phillips), nationally syndicated advice columnist “It’s never too early to imagine what your life will look like as you age. And as I once wrote, ‘We are not hostages to our fate.’ Petrow’s book will help you plan, think, and redefine what it means to get older—and even laugh while doing it.” —Andrew Weil, MD, New York Times bestselling author of Spontaneous Healing and Healthy Aging: A Lifelong Guide to Your Well-Being “Steven Petrow not only has a great attitude about life, he is wise about how to live it. Like me, he says we should embrace our one life 100% and not let a number—our age—get in the way of anything! Steven’s book will help you rethink the word “aging” and approach this next chapter with a positive and proactive attitude. Plus, this book is fun!” —Denise Austin, renowned fitness expert, author, and columnist “Steven’s writing feels like sitting with a friend—one who is unusually gracious, warm and frank.” —Carolyn Hax, author of the nationally syndicated advice column, Carolyn Hax Praise for Steven Petrow: "Steven Petrow's Complete Gay & Lesbian Manners helps gays and straights navigate the subtleties of the same-sex world." —People "Move over, Emily Post! When it comes to etiquette for members of the gay, lesbian, bisexual and transgender community—as well as their straight friends, family members and coworkers--author and journalist Steven Petrow is the authority." —TIME "What could've easily become a novelty book has emerged as an exhaustively researched, essential resource thanks to advice columnist and etiquette expert Steven Petrow." —The Advocate "From having kids to planning funerals, Steven Petrow's Complete Gay & Lesbian Manners has most facets of gay life covered. Ms. Post would approve." —Entertainment Weekly "An indispensable refresher course...on what's proper in modern...life." —Kirkus Reviews
What will you do when you get the call that a loved one has had a heart attack or a stroke? Or when you realize that a family member is too frail to live alone, but too healthy for a nursing home? Journalist Paula Span shares the resonant narratives of several families who faced these questions. Each family contemplates the alternatives in elder care (from assisted living to multigenerational living to home care, nursing care, and at the end, hospice care) and chooses the right path for its needs. Span writes about the families' emotional challenges, their practical discoveries, and the good news that some of them find a situation that has worked for them and their loved ones. And many find joy in the duty of caring for an older loved one. There are 45 million Americans caring for family members currently, and as the 77 million boomers continue to age, this number will only go up. Paula Span's stories are revealing and informative. They give a sense of all the emotional and practical factors that go into the major decisions about caregiving, so that readers will be better able to figure out what to do when the time comes for them and their loved ones.
Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism's deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
Would you like to grow in life-giving ways as you age? Do you have the courage to let go of former ways of thinking to receive God's love and life in new ways? As we age, we experience the loss of physical stamina, independence, and career fulfillment. Yet within each of these losses is a holy invitation to grow. God calls us to let go of our need for accomplishment and embrace the gift of fruitfulness so that we might be transformed in this final season of our lives. In Aging Faithfully, spiritual director Alice Fryling explores how to navigate the journey of retirement, lifestyle changes, and new limitations. In this season of life, we are invited to hold both grief and hope, to acknowledge ways of thinking that no longer represent who we are, and to receive peace in the midst of our fears. We all age differently, and God calls each of us to new spiritual birth as we mature. When we embrace the aging process, we grow closer to God and experience his grace as he renews us from within. Whether you are approaching the beginning, middle, or end of your senior years, you are invited. Come and be transformed. Aging Faithfully includes questions for group discussion and suggestions for personal meditation.
The United States is in the midst of a major demographic shift. In the coming decades, people aged 65 and over will make up an increasingly large percentage of the population: The ratio of people aged 65+ to people aged 20-64 will rise by 80%. This shift is happening for two reasons: people are living longer, and many couples are choosing to have fewer children and to have those children somewhat later in life. The resulting demographic shift will present the nation with economic challenges, both to absorb the costs and to leverage the benefits of an aging population. Aging and the Macroeconomy: Long-Term Implications of an Older Population presents the fundamental factors driving the aging of the U.S. population, as well as its societal implications and likely long-term macroeconomic effects in a global context. The report finds that, while population aging does not pose an insurmountable challenge to the nation, it is imperative that sensible policies are implemented soon to allow companies and households to respond. It offers four practical approaches for preparing resources to support the future consumption of households and for adapting to the new economic landscape.
Why does time seem to speed up as we grow older? Do you want to learn the secret of how to slow it down? Now you can! With access to in-depth research, you can learn how to extend the good times and fast forward through the bad ones with "The Power of Time Perception."
In Ripening Time: Inside Stories for Aging with Grace, Sherry Ruth Anderson presents a new perspective on aging. In her latest book, the bestselling author of The Feminine Face of God and The Cultural Creatives invites the reader to engage the aging process through the art of inner inquiry. She guides us beyond our culture's mind traps through stories where elders face into the lies, the losses and endings, the tender and bittersweet and ferocious truths of growing old. Giving us an indispensable compass, she shows how growing into old age can be a fruition, the genuine grace and gift of human ripening. ,
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
