Advances in Pharmacology. Vol. 56, HIV-1 : Molecular Biology and Pathogenesis
Author:
Publisher:
Published: 2008
Total Pages: 593
ISBN-13:
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HIV-1: Molecular Biology and Pathogenesis: Viral Mechanisms
Author:
Publisher: Elsevier
Published: 2007-06-13
Total Pages: 488
ISBN-13: 0080548326
DOWNLOAD EBOOKThis volume covers the latest advances in the mechanisms of pathogenesis of the HIV-1 virus on target cells. Its companion volume, Advances in Pharmacology 56, shows how new developments in understanding the virus translate to the clinical setting.
HIV: Molecular Biology and Pathogenesis: Viral Mechanisms
Author:
Publisher: Academic Press
Published: 2000-09-07
Total Pages: 524
ISBN-13: 0080553923
DOWNLOAD EBOOKThe cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia. - Detailed insights into viral packaging, expression, and assembly - Mechanistic understanding of how HIV interacts with receptors and infects cells - Delineation of virally encoded regulatory processes unique to HIV - Clinical Applications: - An updated review of current chemotherapeutics for HIV - New concepts in the discovery and design of novel anti-HIV drugs - The latest developments in HIV-vaccine research
HIV I: Molecular Biology and Pathogenesis: Clinical Applications
Author:
Publisher: Academic Press
Published: 2000-09-26
Total Pages: 561
ISBN-13: 0080549861
DOWNLOAD EBOOKThe cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia. - Detailed insights into viral packaging, expression, and assembly - Mechanistic understanding of how HIV interacts with receptors and infects cells - Delineation of virally encoded regulatory processes unique to HIV - Clinical Applications: - An updated review of current chemotherapeutics for HIV - New concepts in the discovery and design of novel anti-HIV drugs - The latest developments in HIV-vaccine research
HIV I: Molecular Biology and Pathogenesis: Clinical Applications
Author:
Publisher: Academic Press
Published: 2007-12-14
Total Pages: 637
ISBN-13: 0080557228
DOWNLOAD EBOOKAlthough it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad: HIV-1: Molecular Biology and Pathogenesis, Second Edition. Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. The latest developments in HIV-vaccine research New concepts in the discovery and design of novel anti-HIV drugs
HIV: Molecular Biology and Pathogenesis: Viral Mechanisms
Author:
Publisher: Academic Press
Published: 2000-08-25
Total Pages: 0
ISBN-13: 9780120329496
DOWNLOAD EBOOKThe cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines. The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.
Analogue-based Drug Discovery II
Author: János Fischer
Publisher: John Wiley & Sons
Published: 2010-08-24
Total Pages: 563
ISBN-13: 3527632123
DOWNLOAD EBOOKBorn out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog discovery and development. Spanning a wide range of therapeutic fields and chemical classes, the two volumes together constitute the first systematic approach to drug analog development. Of interest to virtually every researcher working in drug discovery and pharmaceutical chemistry.
HIV-1 Latency
Author: Guido Silvestri
Publisher: Springer
Published: 2018-10-11
Total Pages: 253
ISBN-13: 303002816X
DOWNLOAD EBOOKThis volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
