Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
Author: Carlos A. Vaccaro
Publisher: Frontiers Media SA
Published: 2023-01-27
Total Pages: 108
ISBN-13: 2832512127
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Genetics of Colorectal Cancer
Author: John D. Potter
Publisher: Springer
Published: 2008-12-08
Total Pages: 309
ISBN-13: 9780387095677
DOWNLOAD EBOOKGenetic susceptibility refers to how variations in a person’s genes increase or decrease his or her susceptibility to environmental factors, such as chemicals, radiation and lifestyle (diet and smoking). This volume will explore the latest findings in the area of genetic susceptibility to gastrointestinal cancers, focusing on molecular epidemiology, DNA repair, and gene-environment interactions to identify factors that affect the incidence of GI cancers. Topics will include germline susceptibility, including Mendelian patterns of inheritance and gene-environment interactions that lead to cancer etiology.
Hereditary Colorectal Cancer
Author: Miguel A. Rodriguez-Bigas
Publisher: Springer Science & Business Media
Published: 2010-09-10
Total Pages: 615
ISBN-13: 144196603X
DOWNLOAD EBOOKColorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.
Hereditary Colorectal Cancer
Author: Laura Valle
Publisher: Springer
Published: 2018-05-04
Total Pages: 494
ISBN-13: 3319742590
DOWNLOAD EBOOKThis book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.
Genetic Epidemiology of Cancer
Author: Henry T. Lynch
Publisher: CRC Press
Published: 1989-06-30
Total Pages: 376
ISBN-13: 9780849367564
DOWNLOAD EBOOKThis multi-authored book provides a unique accounting of the cancer problem from the standpoint of those primary genetic factors which may be interacting with myriad environmental exposures in cancer etiology. It provides a comprehensive coverage of cancer of all anatomical sites in conjunction with a genetic/environmental thrust. It includes a survey chapter dealing with the role of primary genetic factors in cancer of differing anatomic sites and a similar comprehensive survey chapter tracing the history of epidemiology, with focus upon multiple anatomic sites, including classical epidemiologic cancer models such as cigarette smoking, asbestos, vinyl chloride, and uranium exposure. Chapters are devoted to tumor biomarkers and their applicability to cancer of multiple anatomic sites. Clinical correlation will involve surveillance/management programsand focus on high-risk groups-such as those involving primary genetic or environmental factors and/or their interaction. The development of registries involving families with differing hereditary cancer syndromes are considered. Also, many chapters are devoted to environmental protective measures, as well as the need for more responsibility for coverage of patients at inordinately high risk for cancer by third party carriers. Other chapters address segregation and linkage analysis, oncogenes, cytogenetics, and other biomarkers. This book will be of interest to general clinicians, oncologists, surgeons, geneticists, and carcinogenesis investigators.
Assessing Genetic Risks
Author: Institute of Medicine
Publisher: National Academies Press
Published: 1994-01-01
Total Pages: 353
ISBN-13: 0309047986
DOWNLOAD EBOOKRaising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
WHO Classification of Tumours of the Digestive System
Author: F. T. Bosman
Publisher: International Agency for Research on Cancer
Published: 2010-10-15
Total Pages: 424
ISBN-13:
DOWNLOAD EBOOK"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].
Histological Typing of Tumours of the Exocrine Pancreas
Author: G. Klöppel
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 84
ISBN-13: 3642610242
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Prevention and Early Detection of Colorectal Cancer
Author: Graeme P. Young
Publisher: W.B. Saunders Company
Published: 1996
Total Pages: 410
ISBN-13:
DOWNLOAD EBOOKThis is an overview of the issues involved in prevention and early detection of colorectal cancer providing up-to-date, practical advice for clinicians. Possible management strategies for those at risk are provided, taking into account the biological principles of colorectal cancer development, epidemiological data and emerging genetic information, as well as social and environmental factors.
How Tobacco Smoke Causes Disease
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
Published: 2010
Total Pages: 728
ISBN-13:
DOWNLOAD EBOOKThis report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
