This book represents the third in a series of International Conferences related to Alzheimer's (AD) and Parkinson's (PD) diseases. The first one took place in Eilat, Israel, in 1985; and the second one in Kyoto, Japan, in 1989. This book contains the full text of oral and poster presentations from the Third International Conference on Alzheimer's and Parkinson's Diseases: Recent Developments, held in Chicago, Illinois, U.S.A. on November 1-6, 1993. The Chicago Conference was attended by 270 participants. The Scientific Program was divided into nine oral sessions, a keynote presentation, and a poster session. The conference culminated in a Round Table Discussion involving all of the participants in the conference. The four and one-half day meeting served as an excellent medium for surveying the current status of clinical and preclinical developments in AD and PD. There were 59 oral presentations and 93 posters. This book incorporates a majority of both.
This volume contains the proceedings of the 2005 ADPD conference and is unique in that it deals not only with issues related individually to Alzheimer’s disease and Parkinson’s disease, but also with the integration of these and other related diseases. The most up-to-date techniques and research findings are illustrated in this volume, which covering topics from immunology, neuroscience, and pharmacology to genetics and molecular biology. Possible future developments in the treatment of Alzheimer’s and Parkinson’s Diseases are also covered.
Filling a noticeable gap in the market for a new text solely focused on Dementia with Lewy Bodies, this book discusses cutting-edge topics covering the condition from diagnosis to management, as well as what is known about the neurobiological changes involved. With huge progress having been made over the last decade in terms of the disorder
Dementia, technically defined as cognitive impairments sufficiently pervasive and severe enough that they disrupt independent life, is one of the most devastating symptoms of neurologic disease. While Alzheimer's disease (AD) is the most common neurodegenerative disease that causes it, more than 50 medical, psychiatric, and neurological conditions are associated with dementia. Well organized and expertly planned, this text provides new concepts of patient management that have come about through recent neuroscience research. This volume, reviewing the dementias with the needs of the clinician in mind, is unique in that the section dealing with disease mechanisms reviews the exciting recent scientific advance in regard to Alzheimer disease, whereas the clinical section(section A) focuses not on Alzheimer disease but upon related disorders, the less common dementing syndromes due to other neurodegenerative disorders. The editors of this Blue Book have brought together an extraordinary group of experts to define the scientific advances primarily in Alzheimer's disease (section B) and new treatments (section C) being developed. * Written for non-expert general neurologists and residents * Provides new concepts of patient management discovered in neuroscience research * Includes unique coverage of recent scientific advances in Alzheimer's Disease
There is a looming threat, hovering like the Sword of Damocles. For whom the freaking bell tolls? We are all increasingly at grave risk for neurological disorders, including Alzheimer's, dementia, and Parkinson's - diseases that inflict a staggering toll on the afflicted and their loved ones. Most troubling, current pharmacological interventions are not cures and do not often provide needed relief. This book will inform and empower you to develop a plan of action to help you or your loved one fight against Alzheimer's, Parkinson's, and other neurological disorders. Informed by relevant research, this book shows that movement or exercise, particularly when combined with music, can have a powerful impact on brain health. The scientific research is also illuminated and amplified by the lived experiences of people whose stories reveal how movement, exercise, and dance therapy are helping them in the struggle against neurological disorders. Movement + Music = Medicine will increase your knowledge about the medicinal impact of rhythmic movement and give you greater confidence to make decisions that may improve your brain health. While movement, exercise, and dance are by no means cures for these cruel neurologic conditions, they may provide sorely needed relief and give you a fighting chance at a better quality of life.Reviews and praise for Movement + Music = Medicine"This well-researched book with intriguing and insightful anecdotes makes a substantial contribution towards understanding how movement, particularly dance, may help slow the course of Alzheimer's and Parkinson's diseases. The book is especially relevant and timely, given the alarming increase in the two diseases - medical conditions often associated with aging but highly variable between patients. Movement + Music = Medicine is highly recommended for a general audience seeking to learn more about neurological disorders and how lifestyle changes, particularly movement, exercise, and dance, may make a difference." Arthur S. Levine, M.D. Executive Director, University of Pittsburgh Brain Institute, Professor of Medicine, Molecular Genetics, and Neurobiology."Dr. Spectar has created a masterpiece combining the history of dance across culture and time and the evidence to support brain health and combatting neurodegenerative disease... I am convinced, I will now be prescribing dance to my patients, for lasting limberness of the brain and the body."Mylynda B. Massart, M.D., Ph.D., Physician and co-director, Pitt Clinical and Translational Science Institute."I have never seen a compilation of science and humanities so beautifully intertwined-like a dance in and of itself! ... Through the lens of health and healing, Dr. Jem Spectar masterfully crafts the interrelationship between science and art as supported by a vast collection of empirical data, multicultural applications, and personal narratives that argue for the critical need of dance and movement to sustain a healthy society... Movement + Music = Medicine provides a substantial contribution to the growing field of Medical Humanities within medical schools, graduate studies, residency programs, public health departments, and, of course, dance... [This] book is phenomenal!"Susan Wieczorek, Ph.D., Associate Professor of Communications, UPJ."As caregiver for a spouse struggling with late-stage Alzheimer's Disease, reading this enormously resourceful book makes me wonder what life for us might be like today if the book had been available earlier in our journey... Dr. Spectar's book appears to fill a void in therapeutic resources for Alzheimer's Disease patients and caregivers... I highly recommend this book for anyone who suspects a neurological disease may become an issue in their family. It's a must read for newly diagnosed patients with a neurological disease and for family members caring for patients who are advancing through various stages of the diseases." Livy - a caregiver
Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental states and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. Research Anthology on Diagnosing and Treating Neurocognitive Disorders examines the treatment, diagnosis, prevention, and therapeutic and technological interventions of neurodegenerative disorders. It also describes programs and strategies that professional and family caregivers can implement to engage and improve the quality of life of persons suffering from cognitive impairment. Highlighting a range of topics such as dementia, subjective wellbeing, and cognitive decline, this publication is an ideal reference source for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neurocognitive disorder identification and strategies for clinician support and therapies.
Drug Design and Discovery in Alzheimer's Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of ß-amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery. - Edited and written by leading experts in Alzheimer's disease (AD) and other neurodegenerative disease drug development - Describes existing drugs for AD and current molecular understanding of the condition - Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets
