Advanced Photon Counting
Advanced Photon Counting

Author: Peter Kapusta

Publisher: Springer

Published: 2015-04-23

Total Pages: 371

ISBN-13: 3319156365

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This volume focuses on Time-Correlated Single Photon Counting (TCSPC), a powerful tool allowing luminescence lifetime measurements to be made with high temporal resolution, even on single molecules. Combining spectrum and lifetime provides a “fingerprint” for identifying such molecules in the presence of a background. Used together with confocal detection, this permits single-molecule spectroscopy and microscopy in addition to ensemble measurements, opening up an enormous range of hot life science applications such as fluorescence lifetime imaging (FLIM) and measurement of Förster Resonant Energy Transfer (FRET) for the investigation of protein folding and interaction. Several technology-related chapters present both the basics and current state-of-the-art, in particular of TCSPC electronics, photon detectors and lasers. The remaining chapters cover a broad range of applications and methodologies for experiments and data analysis, including the life sciences, defect centers in diamonds, super-resolution microscopy, and optical tomography. The chapters detailing new options arising from the combination of classic TCSPC and fluorescence lifetime with methods based on intensity fluctuation represent a particularly unique highlight.

Analog Electronics for Radiation Detection
Analog Electronics for Radiation Detection

Author: Renato Turchetta

Publisher: CRC Press

Published: 2017-12-19

Total Pages: 257

ISBN-13: 1351830228

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Analog Electronics for Radiation Detection showcases the latest advances in readout electronics for particle, or radiation, detectors. Featuring chapters written by international experts in their respective fields, this authoritative text: Defines the main design parameters of front-end circuitry developed in microelectronics technologies Explains the basis for the use of complementary metal–oxide semiconductor (CMOS) image sensors for the detection of charged particles and other non-consumer applications Delivers an in-depth review of analog-to-digital converters (ADCs), evaluating the pros and cons of ADCs integrated at the pixel, column, and per-chip levels Describes incremental sigma–delta ADCs, time-to-digital converter (TDC) architectures, and digital pulse-processing techniques complementary to analog processing Examines the fundamental parameters and front-end types associated with silicon photomultipliers used for single visible-light photon detection Discusses pixel sensors with per-pixel TDCs, channel density challenges, and emerging 3D technologies interconnecting detectors and electronics Thus, Analog Electronics for Radiation Detection provides a single source for state-of-the-art information on analog electronics for the readout of radiation detectors.

Advanced Time-Correlated Single Photon Counting Techniques
Advanced Time-Correlated Single Photon Counting Techniques

Author: Wolfgang Becker

Publisher: Springer Science & Business Media

Published: 2005-12-19

Total Pages: 414

ISBN-13: 3540288821

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In 1984 Desmond O’Connor and David Phillips published their comprehensive book „Time-correlated Single Photon Counting“. At that time time-correlated s- gle photon counting, or TCSPC, was used primarily to record fluorescence decay functions of dye solutions in cuvettes. From the beginning, TCSPC was an am- ingly sensitive and accurate technique with excellent time-resolution. However, acquisition times were relatively slow due to the low repetition rate of the light sources and the limited speed of the electronics of the 70s and early 80s. Moreover, TCSPC was intrinsically one-dimensional, i.e. limited to the recording of the wa- form of a periodic light signal. Even with these limitations, it was a wonderful te- nique. More than 20 years have elapsed, and electronics and laser techniques have made impressive progress. The number of transistors on a single chip has approximately doubled every 18 months, resulting in a more than 1,000-fold increase in compl- ity and speed. The repetition rate and power of pulsed light sources have increased by about the same factor.

Advances in Imaging and Sensing
Advances in Imaging and Sensing

Author: Shuo Tang

Publisher: CRC Press

Published: 2016-10-26

Total Pages: 236

ISBN-13: 1315354101

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This introductory, yet in-depth, book explains the physical principles of electronic imaging and sensing and provides the reader with the information necessary to understand the design, operation, and practical applications of contemporary electronic imaging and sensing systems. The text has strong practical focus and contains examples of biomedical applications of optical electronic imaging and sensing. Each chapter draws upon the authors’ extensive research, teaching, and industrial experience and provides a useful resource for undergraduate and graduate students, as well as a convenient reference for scientists and engineers working in the field of electronic imaging and sensing.

Time-correlated single photon counting
Time-correlated single photon counting

Author: Desmond O'Connor

Publisher: Academic Press

Published: 2012-12-02

Total Pages: 299

ISBN-13: 0323141447

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Time-correlated Single Photon Counting has been written in the hope that by relating the authors' experiences with a variety of different single photon counting systems, they may provide a useful service to users and potential users of this formidably sensitive technique. Of all the techniques available to obtain information on the rates of depopulation of excited electronic singlet states of molecular species, monitoring of fluorescence provides, in principle, the simplest and most direct measure of concentration. This volume comprises eight chapters, with the first focusing on the time dependence and applications of fluorescence. Succeeding chapters go on to discuss basic principles of the single photon counting lifetime measurement; light sources; photomultipliers; electronics; data analysis; nanosecond time-resolved emission spectroscopy; time dependence of fluorescence anisotropy. This book will be of interest to practitioners in the field of chemistry.

Radiation Effects in Semiconductors
Radiation Effects in Semiconductors

Author: Krzysztof Iniewski

Publisher: CRC Press

Published: 2018-09-03

Total Pages: 442

ISBN-13: 1351833758

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Space applications, nuclear physics, military operations, medical imaging, and especially electronics (modern silicon processing) are obvious fields in which radiation damage can have serious consequences, i.e., degradation of MOS devices and circuits. Zeroing in on vital aspects of this broad and complex topic, Radiation Effects in Semiconductors addresses the ever-growing need for a clear understanding of radiation effects on semiconductor devices and circuits to combat potential damage it can cause. Features a chapter authored by renowned radiation authority Lawrence T. Clark on Radiation Hardened by Design SRAM Strategies for TID and SEE Mitigation This book analyzes the radiation problem, focusing on the most important aspects required for comprehending the degrading effects observed in semiconductor devices, circuits, and systems when they are irradiated. It explores how radiation interacts with solid materials, providing a detailed analysis of three ways this occurs: Photoelectric effect, Compton effect, and creation of electron-positron pairs. The author explains that the probability of these three effects occurring depends on the energy of the incident photon and the atomic number of the target. The book also discusses the effects that photons can have on matter—in terms of ionization effects and nuclear displacement Written for post-graduate researchers, semiconductor engineers, and nuclear and space engineers with some electronics background, this carefully constructed reference explains how ionizing radiation is creating damage in semiconducting devices and circuits and systems—and how that damage can be avoided in areas such as military/space missions, nuclear applications, plasma damage, and X-ray-based techniques. It features top-notch international experts in industry and academia who address emerging detector technologies, circuit design techniques, new materials, and innovative system approaches.

An Introduction to Distributed Optical Fibre Sensors
An Introduction to Distributed Optical Fibre Sensors

Author: Arthur H. Hartog

Publisher: CRC Press

Published: 2017-05-25

Total Pages: 471

ISBN-13: 1482259583

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This book explains physical principles, unique benefits, broad categories, implementation aspects, and performance criteria of distributed optical fiber sensors (DOFS). For each kind of sensor, the book highlights industrial applications, which range from oil and gas production to power line monitoring, plant and process engineering, environmental monitoring, industrial fire and leakage detection, and so on. The text also includes a discussion of such key areas as backscattering, launched power limitations, and receiver sensitivity, as well as a concise historical account of the field’s development.

Quantum Photonics: Pioneering Advances and Emerging Applications
Quantum Photonics: Pioneering Advances and Emerging Applications

Author: Robert W. Boyd

Publisher: Springer

Published: 2019-02-19

Total Pages: 646

ISBN-13: 3319984020

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This book brings together reviews by internationally renowed experts on quantum optics and photonics. It describes novel experiments at the limit of single photons, and presents advances in this emerging research area. It also includes reprints and historical descriptions of some of the first pioneering experiments at a single-photon level and nonlinear optics, performed before the inception of lasers and modern light detectors, often with the human eye serving as a single-photon detector. The book comprises 19 chapters, 10 of which describe modern quantum photonics results, including single-photon sources, direct measurement of the photon's spatial wave function, nonlinear interactions and non-classical light, nanophotonics for room-temperature single-photon sources, time-multiplexed methods for optical quantum information processing, the role of photon statistics in visual perception, light-by-light coherent control using metamaterials, nonlinear nanoplasmonics, nonlinear polarization optics, and ultrafast nonlinear optics in the mid-infrared.

Single-Photon Generation and Detection
Single-Photon Generation and Detection

Author:

Publisher: Academic Press

Published: 2013-11-29

Total Pages: 593

ISBN-13: 0123876966

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Single-photon generation and detection is at the forefront of modern optical physics research. This book is intended to provide a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared. The use of single photons, produced on demand with well-defined quantum properties, offers an unprecedented set of capabilities that are central to the new area of quantum information and are of revolutionary importance in areas that range from the traditional, such as high sensitivity detection for astronomy, remote sensing, and medical diagnostics, to the exotic, such as secretive surveillance and very long communication links for data transmission on interplanetary missions. The goal of this volume is to provide researchers with a comprehensive overview of the technology and techniques that are available to enable them to better design an experimental plan for its intended purpose. The book will be broken into chapters focused specifically on the development and capabilities of the available detectors and sources to allow a comparative understanding to be developed by the reader along with and idea of how the field is progressing and what can be expected in the near future. Along with this technology, we will include chapters devoted to the applications of this technology, which is in fact much of the driver for its development. This is set to become the go-to reference for this field. - Covers all the basic aspects needed to perform single-photon experiments and serves as the first reference to any newcomer who would like to produce an experimental design that incorporates the latest techniques - Provides a comprehensive overview of the current status of single-photon techniques and research methods in the spectral region from the visible to the infrared, thus giving broad background that should enable newcomers to the field to make rapid progress in gaining proficiency - Written by leading experts in the field, among which, the leading Editor is recognized as having laid down the roadmap, thus providing the reader with an authenticated and reliable source