Molecular Cell Biology

Molecular Cell Biology

Author: Harvey F. Lodish

Publisher: Scientific American Library

Published: 2000

Total Pages: 1192

ISBN-13:

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With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.


Molecular Biology of the Cell 6E - The Problems Book

Molecular Biology of the Cell 6E - The Problems Book

Author: John Wilson

Publisher: Garland Science

Published: 2014-11-21

Total Pages: 984

ISBN-13: 1317497279

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The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be


Advanced Molecular Biology

Advanced Molecular Biology

Author: Richard M. Twyman

Publisher: Taylor & Francis

Published: 1998

Total Pages: 499

ISBN-13: 9781859961414

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Advanced Molecular Biology - A Concise Reference provides in-depth coverage of 30 essential topics in molecular biology with particular focus on genetic information and its expression. The book emphasizes unifying principles and mechanisms, with comprehensive use of tables and boxes to summarize experimental data, gene and protein functions. Advanced Molecular Biology - A Concise Reference is written for upper level undergraduates, postgraduates and academics with an interest in molecular biology who need a convenient entry into the field.


Advanced Imaging in Biology and Medicine

Advanced Imaging in Biology and Medicine

Author: Ch.W. Sensen

Publisher: Springer Science & Business Media

Published: 2008-12-03

Total Pages: 447

ISBN-13: 3540689931

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A picture says more than a thousand words. This is something that we all know to be true. Imaging has been important since the early days of medicine and bi- ogy, as seen in the anatomical studies of Leonardo Da Vinci or Andreas Vesalius. More than 100 years ago, the ?rst noninvasive imaging technologies, such as K- rad Roentgen’s X-ray technology,were applied to the medical ?eld—and while still crude—revolutionized medical diagnosis. Today, every patient will be exposed to some kind of advanced imaging technology such as medical resonance imaging, computed tomography or four-dimensional ultrasound during their lifetime. Many diseases, such as brain tumors, are initially diagnosed solely by imaging, and most of the surgical planning relies on the patient imagery. 4D ultrasound is available to expecting parents who wish to create unique early memories of the new baby, and it may soon be used for the morphometric diagnosis of malformations that may one day be treatable—inutero! Light and electron microscopy are unequal brethren, which have contributed to most of our knowledge about the existence and organization of cells, tissues and microorganisms. Every student of biology or medicine is introduced to the fascinating images of the microcosm. New advances have converted these im- ing technologies, which were considered by many to be antiquated, into powerful tools for research in systems biology and related ?elds.


Computational Cell Biology

Computational Cell Biology

Author: Christopher P. Fall

Publisher: Springer Science & Business Media

Published: 2007-06-04

Total Pages: 484

ISBN-13: 0387224599

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This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.


Systems Biology of Cell Signaling

Systems Biology of Cell Signaling

Author: James Ferrell

Publisher: Garland Science

Published: 2021-09-28

Total Pages: 285

ISBN-13: 1000430731

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How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download


Mammalian Development

Mammalian Development

Author: Patrick P. L. Tam

Publisher:

Published: 2013

Total Pages: 0

ISBN-13: 9781936113248

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"A subject collection from Cold Spring Harbor perspectives in biology."


The P53 Protein

The P53 Protein

Author: Guillermina Lozano

Publisher:

Published: 2016

Total Pages: 0

ISBN-13: 9781621821335

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Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic stress. In recent years, p53 research has begun to move into the clinic in attempts to understand how p53 is frequently inactivated in-and sometimes even promotes-human cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the rapid progress that has recently been made in basic and clinical research on p53. The contributors review new observations about its basic biology, providing updates on the functions of its isoforms and domains, the myriad stresses and signals that trigger its activation or repression, and its downstream effects on genome stability and the cell cycle that enforce tumor suppression in different cell and tissue types. They also discuss how p53 dysfunction contributes to cancer, exploring the various inherited and somatic mutations in the human TP53 gene, the impact of mutant p53 proteins on tumorigenesis, and the prognostic value and clinical outcomes of these mutations. Drugs that are being developed to respond to tumors harboring aberrant p53 are also described. This book is therefore essential reading for all cancer biologists, cell and molecular biologists, and pharmacologists concerned with the treatment of this disease.