Sam Capra - brilliant CIA agent, loving husband, expectant father - loses everything that matters to him in a horrifying moment in London. An unknown enemy has set him up as a traitor. But that enemy has targeted the wrong man. Escaping from the CIA, Sam goes on a desperate hunt for the killer who stole his family and to save his kidnapped wife and child. But the destruction of Sam's life was only step one in an extraordinary plot - and now Sam Capra must become a new kind of hero.
Inducing highs of excitement, anger, and terror, adrenaline fuels the extremes of human experience. A rush empowers superhuman feats in emergencies. Risk-taking junkies seek to replicate this feeling in dangerous recreations. And a surge may literally scare us to death. Adrenaline brings us up to speed on the fascinating molecule that drives some of our most potent experiences. Adrenaline was discovered in 1894 and quickly made its way out of the lab into clinics around the world. In this engrossing account, Brian Hoffman examines adrenaline in all its capacities, from a vital regulator of physiological functions to the subject of Nobel Prize–winning breakthroughs. Because its biochemical pathways are prototypical, adrenaline has had widespread application in hormone research leading to the development of powerful new drugs. Hoffman introduces the scientists to whom we owe our understanding, tracing the paths of their discoveries and aspirations and allowing us to appreciate the crucial role adrenaline has played in pushing modern medicine forward. Hoffman also investigates the vivid, at times lurid, place adrenaline occupies in the popular imagination, where accounts of its life-giving and lethal properties often leave the realm of fact. Famous as the catalyst of the “fight or flight” response, adrenaline has also received forensic attention as a perfect poison, untraceable in the bloodstream—and rumors persist of its power to revive the dead. True to the spirit of its topic, Adrenaline is a stimulating journey that reveals the truth behind adrenaline’s scientific importance and enduring popular appeal.
Psychologist Archibald D. Hart theorizes that heart attacks and other stress-induced illness are the lethal by-products of too much adrenaline pumping through our systems. He suggests ways to minimize these threats through adjustments in values and lifestyles.
This accessible work is the first in more than seventy-five years to discuss the many roles of adrenaline in regulating the "inner world" of the body. David S. Goldstein, an international authority and award-winning teacher, introduces new concepts concerning the nature of stress and distress across the body's regulatory systems. Discussing how the body's stress systems are coordinated, and how stress, by means of adrenaline, may affect the development, manifestations, and outcomes of chronic diseases, Goldstein challenges researchers and clinicians to use scientific integrative medicine to develop new ways to treat, prevent, and palliate disease. Goldstein explains why a former attorney general with Parkinson disease has a tendency to faint, why young astronauts in excellent physical shape cannot stand up when reexposed to Earth's gravity, why professional football players can collapse and die of heat shock during summer training camp, and why baseball players spit so much. Adrenaline and the Inner World is designed to supplement academic coursework in psychology, psychiatry, endocrinology, cardiology, complementary and alternative medicine, physiology, and biochemistry. It includes an extensive glossary.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
The book examines the noradrenaline-emotional psyches (brain-blood barrier) somatic-adrenaline axis. It conceptually updates research advances, diagnostic techniques and therapeutic methods. The authors enhance their discussions with clear illustrations and explicative texts written for researchers, professionals, educators and students alike, which favour its selection as an essential overview of recent medical and scientific advances, allowing the reader to have the satisfaction of finding first-rate accounts of important work. Comparative studies between immediately obtained adrenal vein samples (AVS) and 15 minutes thereafter show that the stress reactions induced by catheter manipulation had an effect on serum cortisol and aldosterone values. A transient increase in cortisol release from both adrenal glands occurs in the majority of the patients who undergo AVS. This stress reaction can influence the assessment of both the selectivity of the catheterisation during the sequential AVS technique and the lateralisation of aldosteronoma bearing gland. The separation of noradrenaline (NA) at brain and adrenaline at blood functions as a homeostatic lame axis by the blood-brain barrier blocking adrenaline feedback in hypothalamic-pituitary-adrenal (HTPA). This leads to postulate an evolution adaptation for the brain dominance over body, which allows a psychoanalytic treatment to function to signal turn-off and return to circadian homeostasis. Decreased glucose could stress the HTPA axis and leads to decreasing metabolites and releasing Mg2+ for integration of the brain-tissue network. Mg2+ changes adenylyl cyclase (AC) from a Ca2+-AC complex to an Mg2+-AC form with responsiveness to NA for short-term memory. The cAMP generated has been postulated for consolidation of long-term memory.
Adrenaline is a powerful hormone whose effects have been virtually ignored by the medical community. Platt explains how this hormone might be a major underlying cause of many conditions currently considered incurable, and presents a natural protocol for rapidly reducing excess adrenaline.
