Active Implants and Scaffolds for Tissue Regeneration
Active Implants and Scaffolds for Tissue Regeneration

Author: Meital Zilberman

Publisher: Springer Science & Business Media

Published: 2011-05-05

Total Pages: 511

ISBN-13: 3642180655

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Active implants are actually drug or protein-eluting implants that induce healing effects, in addition to their regular task, such as support. This effect is achieved by controlled release of the active agent to the surrounding tissue. This book will give a broad overview of biomaterial platforms used as basic elements of drug-eluting implants. It will include mainly coatings for vascular stents with controlled release of antiproliferative agents, wound dressings with controlled release of antibacterial agents, drug-eluting vascular grafts, protein-eluting scaffolds for tissue regeneration, drug-eluting platforms for dental and other applications. Thus, both internal and external implants are described. The drug-eluting implants will be described in terms of matrix formats and polymers, incorporated drugs and their release profiles from the implants, as well as implant functioning. Smart polymeric systems, such as crosslinked poly-lactones, thermo and pH-sensitive hydrogels and poly(amido-amines), as well as novel basic structural elements, such as composite fibers and films, and nanostructures will be thoroughly described. The effect of the processing parameters on the microstructure and on the resulting drug release profiles, mechanical and physical properties, and other relevant properties, will be emphasized. The described new biomaterials approaches for active implants enhance the tools available for creating clinically important biomedical applications.

Biomaterials for Implants and Scaffolds
Biomaterials for Implants and Scaffolds

Author: Qing Li

Publisher: Springer

Published: 2016-11-30

Total Pages: 472

ISBN-13: 3662535742

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This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.

Tissue Adhesives in Clinical Medicine
Tissue Adhesives in Clinical Medicine

Author: James V. Quinn

Publisher: PMPH-USA

Published: 2005

Total Pages: 196

ISBN-13: 9781550092820

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This second edition has expanded the scope and depth of the original text and includes all types of tissue adhesives, their proper indications and their uses. It also adds a final chapter on regulatory issues that contains FDA scientist George Mattamal's perspectives on all adhesives now used clinically or being evaluated by the FDA. The contributors address topics such as the history and background of tissue adhesives, clinical approaches to the use of cyanoacrylate tissue adhesives, protein polymers, and bone cements. The CD-ROM accompanying the book features video demonstrations of techniques. Annotation : 2005 Book News, Inc., Portland, OR (booknews.com).

Bone Tissue Engineering
Bone Tissue Engineering

Author: Jeffrey O. Hollinger

Publisher: CRC Press

Published: 2004-10-14

Total Pages: 462

ISBN-13: 1135501912

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Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Chitosan Based Biomaterials Volume 2
Chitosan Based Biomaterials Volume 2

Author: Jessica Amber Jennings

Publisher: Woodhead Publishing

Published: 2016-09-28

Total Pages: 298

ISBN-13: 0081002564

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Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials. - Presents specific focus on tissue engineering and therapeutics - Provides comprehensive treatment of all biomaterial applications of chitosan - Contains contributions by leading researchers with extensive experience in the material

Tissue Engineering Strategies for Organ Regeneration
Tissue Engineering Strategies for Organ Regeneration

Author: Naznin Sultana

Publisher: CRC Press

Published: 2020-02-04

Total Pages: 185

ISBN-13: 0429749627

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Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

Current Concepts in Dental Implantology
Current Concepts in Dental Implantology

Author: Ilser Turkyilmaz

Publisher: BoD – Books on Demand

Published: 2015-02-25

Total Pages: 278

ISBN-13: 9535117416

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Implant dentistry has changed and enhanced significantly since the introduction of osseointegration concept with dental implants. Because the benefits of therapy became apparent, implant treatment earned a widespread acceptance. Therefore, the need for dental implants has caused a rapid expansion of the market worldwide. Dental implantology continues to excel with the developments of new surgical and prosthodontic techniques, and armamentarium. The purpose of this book named Current Concepts in Dental Implantology is to present a novel resource for dentists who want to replace missing teeth with dental implants. It is a carefully organized book, which blends basic science, clinical experience, and current and future concepts. This book includes ten chapters and our aim is to provide a valuable source for dental students, post-graduate residents and clinicians who want to know more about dental implants.

Handbook of Algal Technologies and Phytochemicals
Handbook of Algal Technologies and Phytochemicals

Author: Gokare A. Ravishankar

Publisher: CRC Press

Published: 2019-07-12

Total Pages: 345

ISBN-13: 0429623437

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Key features: The most comprehensive resource available on the biodiversity of algal species, their industrial production processes and their use for human consumption in food, health and varied applications. Emphasis on basic and applied research, addressing aspects of scale-up for commercial exploitation for the development of novel phytochemicals (phytochemicals from algae). Addresses the underexplored and underutilized potential of chemicals from marine sources for health benefits. Each chapter, written by expert contributors from around the world, includes Summary Points, Figures and Tables, as well as up-to-date references. The first book in this two-volume set explores the diversity of algal constituents for health and disease applications. The commercial value of chemicals of value to food and health is about $6 billion annually, of which 30 percent relates to micro and macro algal metabolites and products for health food applications. This comprenhensive volume looks in detail at algal genomics and metabolomics as well as mass production of microalgae. As a whole, the two-volume set covers all micro and macro algal forms and their traditional uses; their constituents which are of value for food, feed, specialty chemicals, bioactive compounds for novel applications, and bioenergy molecules. Bio-business and the market share of algae-based products are also dealt with, providing global perspectives.

Drug-device Combinations for Chronic Diseases
Drug-device Combinations for Chronic Diseases

Author: SuPing Lyu

Publisher: John Wiley & Sons

Published: 2015-12-07

Total Pages: 288

ISBN-13: 1118120000

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This book covers two areas, the first detailing the concepts and technologies of drug-device combination products. The second area includes case studies of important products that either significantly shape our technologies and thinking, or contribute to current healthcare practice. The book: Discusses where drugs and devices work, where they fail, and when they need to work with each other Reviews interactions between human bodies and the drug-device combination products the measurements of these interactions Covers how a drug-device combination product is developed, tested, and regulated Includes case studies of steroid releasing leads, AOA treated tissue heart valves, intrathecal drug delivery pumps, infuse bone grafts, drug eluting stents, and antimicrobial meshes

Smart Nanoparticles for Biomedicine
Smart Nanoparticles for Biomedicine

Author: Gianni Ciofani

Publisher: Elsevier

Published: 2018-05-12

Total Pages: 270

ISBN-13: 0128141573

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Smart Nanoparticles for Biomedicine explores smart nanoparticles that change their structural or functional properties in response to specific external stimuli (electric or magnetic fields, electromagnetic radiation, ultrasound, etc.). Particular attention is given to multifunctional nanostructured materials that are pharmacologically active and that can be actuated by virtue of their magnetic, dielectric, optically-active, redox-active, or piezoelectric properties. This important reference resource will be of great value to readers who want to learn more on how smart nanoparticles can be used to create more effective treatment solutions. Nanotechnology has enabled unprecedented control of the interactions between materials and biological entities, from the microscale, to the molecular level. Nanosurfaces and nanostructures have been used to mimic or interact with biological microenvironments, to support specific biological functions, such as cell adhesion, mobility and differentiation, and in tissue healing. Recently, a new paradigm has been proposed for nanomedicine to exploit the intrinsic properties of nanomaterials as active devices rather than as passive structural units or carriers for medications. - Discusses the synthesis, characterization and applications of a new generation of smart nanoparticles for nanomedicine applications - Explores the problems relating to the biocompatibility of a range of nanoparticles, outlining potential solutions - Describes techniques for manipulating specific classes of nanoparticles for a variety of treatment types