Index Medicus
Author:
Publisher:
Published: 2001
Total Pages: 1660
ISBN-13:
DOWNLOAD EBOOKVols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
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Redox-Active Therapeutics
Author: Ines Batinić-Haberle
Publisher: Springer
Published: 2016-10-13
Total Pages: 709
ISBN-13: 3319307053
DOWNLOAD EBOOKThis essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.
Metalloenzymes in Denitrification
Author: Isabel Moura
Publisher: Royal Society of Chemistry
Published: 2016-11-15
Total Pages: 468
ISBN-13: 1782623345
DOWNLOAD EBOOKThe reduction of nitrate to nitrogen by metalloenzymes is a vital step in the nitrogen cycle. The importance of this pathway has inspired efforts to understand in greater depth the mechanisms involved. This book presents and discusses the latest information on multiple aspects of denitrification. Written by recognized specialists in the field, this book describes the bioinorganic aspects and the key enzymes involved in denitrification, including their structure, function and mechanisms. Active site modelling, novel methodologies for monitoring denitrification in vivo and biotechnological methods for water treatment are discussed. The book also focusses on the environmental implications of denitrification, such nitrate accumulation and the release of nitrous oxide into the atmosphere from excessive fertiliser use. An important topic in many biological, environmental and agricultural contexts, this book will aid teaching and help bioinorganic chemists and biotechnologists gain an up-to-date picture of the science behind the denitrification process.
Crystal Engineering: From Molecules and Crystals to Materials
Author: Dario Braga
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 502
ISBN-13: 9401145059
DOWNLOAD EBOOKCrystal engineering is an interdisciplinary area that cuts across the traditional subdivisions of chemistry. Fuelled by our increasingly precise understanding of the chemistry and properties of supramolecular systems, interest in the potential of the field has increased rapidly. The topics discussed in the 28 contributions in this book provide a state-of-the-art description of the field and offer new research ideas that, if pursued, will serve to strengthen the field at the interface between supramolecular chemistry and materials science.
Encyclopedia of Supramolecular Chemistry
Author: J. L. Atwood
Publisher: CRC Press
Published: 2004
Total Pages: 1022
ISBN-13: 9780824747237
DOWNLOAD EBOOKCrystallizing a rapidly expanding interdisciplinary field and one of the most popular and newsworthy areas in contemporary chemistry, this two-volume encyclopaedia offers authoritative information with user-friendly and high-quality articles.
Exoplanet Science Strategy
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2019-01-17
Total Pages: 187
ISBN-13: 030947941X
DOWNLOAD EBOOKThe past decade has delivered remarkable discoveries in the study of exoplanets. Hand-in-hand with these advances, a theoretical understanding of the myriad of processes that dictate the formation and evolution of planets has matured, spurred on by the avalanche of unexpected discoveries. Appreciation of the factors that make a planet hospitable to life has grown in sophistication, as has understanding of the context for biosignatures, the remotely detectable aspects of a planet's atmosphere or surface that reveal the presence of life. Exoplanet Science Strategy highlights strategic priorities for large, coordinated efforts that will support the scientific goals of the broad exoplanet science community. This report outlines a strategic plan that will answer lingering questions through a combination of large, ambitious community-supported efforts and support for diverse, creative, community-driven investigator research.
Natural Products in the Chemical Industry
Author: Bernd Schaefer
Publisher: Springer
Published: 2015-05-26
Total Pages: 844
ISBN-13: 3642544614
DOWNLOAD EBOOKNatural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products. This book features diverse compound classes from a number of areas: colourants, fragrances and flavourings, amino acids, pharmaceuticals, hormones, vitamins and agrochemicals. Whether you are a teacher or a scholar, an undergraduate or graduate student, a professional chemist in industry or academia, or someone just interested in natural sciences, this book allows you to be inspired and entertained by facts and information along with enjoyable anecdotes, historical, economic, political, biological and social considerations. Experts in the field can have a pleasurable time cruising through captivating synthesis methods, which enable the generation of complex molecules on industrial scale. This book · deals with the manufacturing of larger quantities of complex molecules (asymmetric and heterocyclic compounds, polycyclic structures, macrocycles and small rings) · displays all reaction schemes in colour, which makes them easy to read · highlights aesthetics and elegance in modern industrial organic chemistry
Chemical Epigenetics
Author: Antonello Mai
Publisher: Springer Nature
Published: 2020-03-31
Total Pages: 569
ISBN-13: 3030429822
DOWNLOAD EBOOKThis book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology. The book also covers the design, synthesis and biological validation of epigenetic chemical modulators, which can be useful as novel chemotherapeutic agents. Particular attention is given to the chemical mechanisms of action of these molecules and to the drug discovery prose which allows their identification. This book will appeal to students who want to know the extensive progresses made by epigenetics (targets and modulators) in the last years from the beginning, and to specialized scientists who need an instrument to quickly search and check historical and/or updated notices about epigenetics.
Molecular Glycobiology
Author: Minoru Fukuda
Publisher:
Published: 1994
Total Pages: 288
ISBN-13:
DOWNLOAD EBOOKCell-surface carbohydrates play critical roles in cell-cell interactions. This well-written book brings together leading researchers to detail major recent advances regarding our understanding of the molecular mechanisms underlying such processes. Emphasis is given to cell type, specific carbohydrate expression, and the carbohydrates and proteins involved in cell recognition. Topics include the molecular structure of animal lectins, carbohydrate recognition in cell-cell interaction, chemical synthesis of oligosaccharides, conformational studies on oligosaccharides, and cell-surface carbohydrates, among others. Also included is a full discussion of key experimental approaches such as chemical synthesis and the three-dimensional structural analysis of carbohydrates. Providing both an up-to-date description of the subject and a forecast of likely future developments, Molecular Glycobiology is a much-needed synopsis of an exciting and rapidly expanding field. It will be welcomed by students and researchers in molecular biology, biochemistry, cell biology, and glycobiology.
Structure Correlation
Author: Hans-Beat Bürgi
Publisher: John Wiley & Sons
Published: 2008-07-11
Total Pages: 936
ISBN-13: 352761608X
DOWNLOAD EBOOKThis book leaves the conventional view of chemical structures far behind: it demonstrates how a wealth of valuable, but hitherto unused information can be extracted from available structural data. For example, a single structure determination does not reveal much about a reaction pathway, but a sufficiently large number of comparable structures does. Finding the 'right' question is as important as is the intelligent use of crystallographic databases. Contributions by F.H. Allen, T.L. Blundell, I.D. Brown, H.B. Bürgi, J.D. Dunitz, L. Leiserowitz and others, authoritatively discuss the structure correlation method as well as illustrative results in detail, covering such apparently unrelated subjects as * Bond strength relations in soldis * Crystal structure prediction * Reaction pathways of organic molecules * Ligand/receptor interactions and enzyme mechanisms This book will be useful to the academic and industrial reader alike. It offers both fundamental aspects and diverse applications of what will surely become a powerful branch of structural chemistry.
