Analysing Gene Expression
Analysing Gene Expression

Author: Stefan Lorkowski

Publisher: John Wiley & Sons

Published: 2006-03-06

Total Pages: 992

ISBN-13: 3527605339

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This book combines the experience of 225 experts on 900 pages. Scientists worldwide are currently overwhelmed by the ever-increasing number and diversity of genome projects. This handbook is your guide through the jungle of new methods and techniques available to analyse gene expression - the first to provide such a broad view of the measurement of mRNA and protein expression in vitro, in situ and even in vivo. Despite this broad approach, detail is sufficient for you to grasp the principles behind each method. In each case, the authors weigh up the advantages and disadvantages, paying particular attention to the automated, high-throughput processing demanded by the biotech industry. Completely up to date, the book covers such ground-breaking methods such as DNA microarrays, serial analysis of gene expression, differential display, and identification of open reading frame expressed sequence tags. All the methods and necessary equipment are presented visually in more than 300 mainly colour illustrations to assist their step-by-step reproduction in your laboratory. Each chapter is rounded off with its own set of extensive references that provide access to detailed experimental protocols. In short, the bible of analysing gene expression.

DNA Computing
DNA Computing

Author: Natasa Jonoska

Publisher: Springer Science & Business Media

Published: 2002-05-28

Total Pages: 404

ISBN-13: 3540437754

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This book constitutes the thoroughly refereed post-proceedings of the 7th International Workshop on DNA-Based Computers, DNA7, held in Tampa, Florida, USA, in June 2001. The 26 revised full papers presented together with 9 poster papers were carefully reviewed and selected from 44 submissions. The papers are organized in topical sections on experimental tools, theoretical tools, probabilistic computational models, computer simulation and sequence design, algorithms, experimental solutions, nano-tech devices, biomimetic tools, new computing models, and splicing systems and membranes.

Surgical Research
Surgical Research

Author: Wiley W. Souba

Publisher: Academic Press

Published: 2001-01-25

Total Pages: 1526

ISBN-13: 9780126553307

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Contributors. -- Foreword. -- Preface. -- Getting Started. -- Assessing Available Information. -- Organizing and Preliminary Planning for Surgical Research -- Writing a Protocol: Animals, Humans, and Use of Biologic, Chemical, and Radiologic Agents. -- Grantsmanship. -- Informed Consent and the Protection of Human Research Subjects: Historical Perspectives and Guide to Current United States Regulations. -- Animal Care and Maintenance. -- Funding Strategies and Agencies: Academic-Industrial Relationships; Intellectual Property. -- Statistical Considerations. -- Use of Nonexperimental Studies to Evaluate Surgical Procedures and Other Interventions: The Challenge of Risk Adjustment. -- Measuring Surgical Outcomes. -- Design of Clinical Trials. -- Using Administrative Data for Clinical Research. -- Research in the Intensive Care Unit: Ethical and Methodological Issues. -- Research in the Operating Room. -- Effects of Age and Gender. -- Strategies, Principles, and Techniques Using Transgeni ...

Human Evolution
Human Evolution

Author: Camilo J. Cela-Conde

Publisher: OUP Oxford

Published: 2007-09-27

Total Pages: 446

ISBN-13: 0191524433

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Human Evolution provides a comprehensive overview of hominid evolution, synthesising data and approaches from fields as diverse as physical anthropology, evolutionary biology, molecular biology, genetics, archaeology, psychology and philosophy. The book starts with chapters on evolution, population genetics, systematics, and the methods for constructing evolutionary trees. These are followed by a comprehensive review of the fossil history of human evolution since our divergence from the apes. Subsequent chapters cover more recent data, both fossil and molecular, relating to the evolution of modern humans. A final section describes the evolution of culture, language, art, and morality. The authors are leading experts in two complementary fields of scholarship, physical anthropology and molecular evolution. Throughout the book they successfully integrate their expertise in evolutionary theory, phylogenetics, genomics, cultural evolution, language, aesthetics and morality to produce a cutting edge textbook, copiously illustrated and with an extensive and up-to-date bibliography. It will be suitable for both senior undergraduate and graduate level students taking courses on human evolution within departments of biology, anthropology, psychology and philosophy. The book will also appeal to a more general audience seeking a readable, up-to-date and inclusive treatment of human origins and evolution.

New Perspectives on the History of Life Sciences and Agriculture
New Perspectives on the History of Life Sciences and Agriculture

Author: Denise Phillips

Publisher: Springer

Published: 2015-02-12

Total Pages: 506

ISBN-13: 3319121855

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This volume explores problems in the history of science at the intersection of life sciences and agriculture, from the mid-eighteenth to the mid-twentieth century. Taking a comparative national perspective, the book examines agricultural practices in a broad sense, including the practices and disciplines devoted to land management, forestry, soil science, and the improvement and management of crops and livestock. The life sciences considered include genetics, microbiology, ecology, entomology, forestry, and deal with US, European, Russian, Japanese, Indonesian, Chinese contexts. The book shows that the investigation of the border zone of life sciences and agriculture raises many interesting questions about how science develops. In particular it challenges one to re-examine and take seriously the intimate connection between scientific development and the practical goals of managing and improving – perhaps even recreating – the living world to serve human ends. Without close attention to this zone it is not possible to understand the emergence of new disciplines and transformation of old disciplines, to evaluate the role and impact of such major figures of science as Humboldt and Mendel, or to appreciate how much of the history of modern biology has been driven by national ambitions and imperialist expansion in competition with rival nations.

From Chromosomes to Mobile Genetic Elements
From Chromosomes to Mobile Genetic Elements

Author: Lee B. Kass

Publisher: CRC Press

Published: 2024-06-27

Total Pages: 282

ISBN-13: 1040032141

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This biography of Nobel Laureate Barbara McClintock (1902-1992) places her life and work in its social, scientific and personal context. The author examines the development of Barbara McClintock’s scientific work and her influence upon individuals and upon the fields of cytogenetics and evolutionary biology in the period from 1902 to the present. The history documents years of McClintock’s notable and lauded scientific work long before she discovered and named transposable elements in the mid-1940s for which she ultimately received the Nobel Prize. The biography employs documented evidence to expose, demystify, and provide clarity for legends and misinterpretations of McClintock’s life and work. Key Features Exposes and demystifies myths and legends told about McClintock’s time in Missouri Clarifies the changing language of genes and genetics Places in perspective the history of McClintock’s research Documents McClintock’s family and early life before college Provides documented details of McClintock’s time in Nazi Germany