A Machine Called Indomitable

A Machine Called Indomitable

Author: Sonny Kleinfield

Publisher: Open Road Media

Published: 2014-04-29

Total Pages: 204

ISBN-13: 1480484695

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The true story of the doctor who invented the MRI: “A fascinating account of how a significant medical development came about” (The New York Times). Dr. Raymond Damadian was plagued with a mysterious and persistent stomach pain, yet physicians assured him that they could find nothing wrong. To find the answer to his ailment, Damadian would spend the ensuing twelve years building a machine that would change medicine. Nuclear magnetic resonance scanning, now called magnetic resonance imaging (MRI), was a revolution: a safe means to determine the makeup of every cell in the human body, distinguishing healthy cells from sick. Although Damadian’s ideas were met with skepticism and outright opposition from the medical community, this machine would go on to save the lives of millions by diagnosing disease while effective treatment was still possible. In short, it was a medical miracle. The story of Damadian’s quest—battling skeptical peers, money troubles, and more with an intensity approaching obsession—is one of the great legends of medical research. Sonny Kleinfield, acclaimed reporter and author, captures Damadian’s remarkable triumph against the odds with compassion and a keen eye. A Machine Called Indomitable is scientific storytelling at its finest.


Imperial Technoscience

Imperial Technoscience

Author: Amit Prasad

Publisher: MIT Press

Published: 2014-03-14

Total Pages: 232

ISBN-13: 0262322072

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A study of science and technology practices that shows how even emergent aspects of research and development remain entangled with established hierarchies. In the last four decades, during which magnetic resonance imaging (MRI) has emerged as a cutting-edge medical technology and a cultural icon, technoscientific imaginaries and practices have undergone a profound change across the globe. Shifting transnational geography of tecchnoscientific innovations is making commonly deployed Euro/West-centric divides such as west versus non-west or “innovating north” versus “non-innovating south” increasingly untenable—the world is indeed becoming flatter. Nevertheless, such dualist divides, which are intimately tied to other dualist categories that have been used to describe scientific knowledge and practice, continue to undergird analyses and imaginaries of transnational technoscience. Imperial Technoscience puts into broad relief the ambivalent and contradictory folding of Euro/west-centrism with emergent features of technoscience. It argues, Euro/West-centric historicism, and resulting over-determinations, not only hide the vibrant, albeit hierarchical, transnational histories of technoscience, but also tell us little about shifting geography of technoscientific innovations. The book utilizes a deconstructive-empirical approach to explore “entangled” histories of MRI across disciplines (physics, chemistry, medicine, etc.), institutions (university, hospitals, industry, etc.), and nations (United States, Britain, and India). Entangled histories of MRI, it shows, better explain emergence and consolidation of particular technoscientific trajectories and shifts in transnational geography of science and technology (e.g. centers and peripheries).


Paul Lauterbur and the Invention of MRI

Paul Lauterbur and the Invention of MRI

Author: M. Joan Dawson

Publisher: MIT Press

Published: 2013-08-23

Total Pages: 362

ISBN-13: 0262316722

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The story behind the invention of the most important medical diagnostic tool since the X-ray. On September 2, 1971, the chemist Paul Lauterbur had an idea that would change the practice of medical research. Considering recent research findings about the use of nuclear magnetic resonance (NMR) signals to detect tumors in tissue samples, Lauterbur realized that the information from NMR signals could be recovered in the form of images—and thus obtained noninvasively from a living subject. It was an unexpected epiphany: he was eating a hamburger at the time. Lauterbur rushed out to buy a notebook in which to work out his idea; he completed his notes a few days later. He had discovered the basic method used in all MRI scanners around the world, and for this discovery he would share the Nobel Prize for Physiology or Medicine in 2003. This book, by Lauterbur's wife and scientific partner, M. Joan Dawson, is the story of Paul Lauterbur's discovery and the subsequent development of the most important medical diagnostic tool since the X-ray. With MRI, Lauterbur had discovered an entirely new principle of imaging. Dawson explains the science behind the discovery and describes Lauterbur's development of the idea, his steadfastness in the face of widespread skepticism and criticism, and related work by other scientists including Peter Mansfield (Lauterbur's Nobel co-recipient), and Raymond Damadian (who famously feuded with Lauterbur over credit for the ideas behind MRI). She offers not only the story of one man's passion for his work but also a case study of how science is actually done: a flash of insight followed by years of painstaking work.


Prize Fight

Prize Fight

Author: Morton Meyers, M.D.

Publisher: St. Martin's Press

Published: 2012-06-05

Total Pages: 273

ISBN-13: 1137000562

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We often think of scientists as dispassionate and detached, nobly laboring without any expectation of reward. But scientific research is much more complicated and messy than this ideal, and scientists can be torn by jealousy, impelled by a need for recognition, and subject to human vulnerability and fallibility. In Prize Fight , Emeritus Chair at SUNY School of Medicine Morton Meyers pulls back the curtain to reveal the dark side of scientific discovery. From allegations of stolen authorship to fabricated results and elaborate hoaxes, he shows us how too often brilliant minds are reduced to petty jealousies and promising careers cut short by disputes over authorship or fudged data. Prize Fight is a dramatic look at some of the most notable discoveries in science in recent years, from the discovery of insulin, which led to decades of infighting and even violence, to why the 2003 Nobel Prize in Medicine exposed how often scientific objectivity is imperiled.


Doctors and Discoveries

Doctors and Discoveries

Author: John Simmons

Publisher: Houghton Mifflin Harcourt

Published: 2002

Total Pages: 488

ISBN-13: 9780618152766

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Traces the history of western medicine through the lives of its major contributors, profiling such well-known figures as Hippocrates and Louis Pasteur, as well as lesser-known scientists including Elle Metchnikoff and Samuel Hahnemann.


A Machine Called Indomitable

A Machine Called Indomitable

Author: Sonny Kleinfield

Publisher:

Published: 2014

Total Pages: 253

ISBN-13:

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The remarkable epic of an invention that revolutionized medicine Dr. Raymond Damadian was plagued with a mysterious and persistent stomach pain, yet physicians assured him that they could find nothing wrong. To find the answer to his ailment, Damadian would spend the ensuing twelve years building a machine that would change medicine. Nuclear magnetic resonance scanning, now called magnetic resonance imaging (MRI), was a revolution: a safe means to determine the makeup of every cell in the human body, distinguishing healthy cells from sick. Although Damadian's ideas were met with skepticism and outright opposition from the medical community, this machine would go on to save the lives of millions by diagnosing disease while effective treatment was still possible. In short, it was a medical miracle. The story of Damadian's quest-battling skeptical peers, money troubles, and more with an intensity approaching obsession-is one of the great legends of medical research. Sonny Kleinfield, acclaimed reporter and author, captures Damadian's remarkable triumph against the odds with compassion and a keen eye. A Machine Called Indomitable is scientific storytelling at its finest. "A fascinating account of how a significant medical development came about." - The New York Times "The backbiting, the infighting, the nastiness, the greed, the need for money, and the genius: A Machine Called Indomitable has it all. It's the way science really works." -Frank Field, senior science editor, CBS-TV "Kleinfield has a fine reporter's eye and ear for detail." - Kirkus Reviews "The story, cogently told by Kleinfield, portrays the interplay of strong personalities which both spurred and hampered a major technological advance of this decade." - Library Journal "Lively." - Publishers Weekly Sonny Kleinfield is a reporter for the New York Times and the author of eight books. He has contributed articles to the Atlantic , Harper's Magazine , Esquire , and Rolling Stone , and was a reporter for the Wall Street Journal before joining the Times . He shared in a Pulitzer Prize for a Times series on race in America, and has received a number of other accolades, including the Robert F. Kennedy Journalism Award, the Meyer Berger Award, an American Society of Newspaper Editors Award, and the Gerald Loeb Award. A native of Fair Lawn, New Jersey, he is a graduate of New York University and lives in New York City.


Drive and Curiosity

Drive and Curiosity

Author: Istvan Hargittai

Publisher: Prometheus Books

Published: 2010-04-13

Total Pages: 330

ISBN-13: 1616144696

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What motivates those few scientists who rise above their peers to achieve breakthrough discoveries? This book examines the careers of fifteen eminent scientists who achieved some of the most notable discoveries of the past century, providing an insider’s perspective on the history of twentieth century science based on these engaging personality profiles. They include: • Dan Shechtman, the 2011 Nobel laureate and discoverer of quasicrystals; • James D. Watson, the Nobel laureate and codiscoverer of the double helix structure of DNA; • Linus Pauling, the Nobel laureate remembered most for his work on the structure of proteins; • Edward Teller, a giant of the 20th century who accomplished breakthroughs in understanding of nuclear fusion; • George Gamow, a pioneering scientist who devised the initially ridiculed and now accepted Big Bang. In each case, the author has uncovered a singular personality characteristic, motivational factor, or circumstance that, in addition to their extraordinary drive and curiosity, led these scientists to make outstanding contributions. For example, Gertrude B. Elion, who discovered drugs that saved millions of lives, was motivated to find new medications after the deaths of her grandfather and later her fiancé. F. Sherwood Rowland, who stumbled upon the environmental harm caused by chlorofluorocarbons, eventually felt a moral imperative to become an environmental activist. Rosalyn Yalow, the codiscoverer of the radioimmunoassay always felt she had to prove herself in the face of prejudice against her as a woman. These and many more fascinating revelations make this a must-read for everyone who wants to know what traits and circumstances contribute to a person’s becoming the scientist who makes the big breakthrough.


Magnetic Appeal

Magnetic Appeal

Author: Kelly Joyce

Publisher: Cornell University Press

Published: 2010-12-15

Total Pages: 208

ISBN-13: 0801460514

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Magnetic Resonance Imaging, not so long ago a diagnostic tool of last resort, has become pervasive in the landscape of consumer medicine; images of the forbidding tubes, with their promises of revelation, surround us in commercials and on billboards. Magnetic Appeal offers an in-depth exploration of the science and culture of MRI, examining its development and emergence as an imaging technology, its popular appeal and acceptance, and its current use in health care. Understood as modern and uncontroversial by health care professionals and in public discourse, the importance of MRI—or its supposed infallibility—has rarely been questioned. In Magnetic Appeal, Kelly A. Joyce shows how MRI technology grew out of serendipitous circumstances and was adopted for reasons having little to do with patient safety or evidence of efficacy. Drawing on interviews with physicians and MRI technologists, as well as ethnographic research conducted at imaging sites and radiology conferences, Joyce demonstrates that current beliefs about MRI draw on cultural ideas about sight and technology and are reinforced by health care policies and insurance reimbursement practices. Moreover, her unsettling analysis of physicians' and technologists' work practices lets readers consider that MRI scans do not reveal the truth about the body as is popularly believed, nor do they always lead to better outcomes for patients. Although clearly a valuable medical technique, MRI technology cannot necessarily deliver the health outcomes ascribed to it. Magnetic Appeal also addresses broader questions about the importance of medical imaging technologies in American culture and medicine. These technologies, which include ultrasound, X-ray, and MRI, are part of a larger trend in which visual representations have become central to American health, identity, and social relations.


Naked to the Bone

Naked to the Bone

Author: Bettyann Kevles

Publisher: Rutgers University Press

Published: 1997

Total Pages: 412

ISBN-13: 9780813523583

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By the late 1960s, the computer and television were linked to produce medical images that were as startling as Roentgen's original X-rays. Computerized tomography (CT) and magnetic reasonance imaging (MRI) made it possible to picture soft tissues invisible to ordinary X-rays. Ultrasound allowed expectant parents to see their unborn children. Positron emission tomography (PET) enabled neuroscientists to map the brain. In this lively history of medical imaging, the first to cover the full scope of the field from X-rays to MRI-assisted surgery, Bettyann Kevles explores the consequences of these developments for medicine and society. Through lucid prose, vivid anecdotes, and more than seventy striking illustrations, she shows how medical imaging has transformed the practice of medicine - from pediatrics to dentistry, neurosurgery to geriatrics, gynecology to oncology. Beyond medicine, Kevles describes how X-rays and the newer technologies have become part of the texture of modern life and culture. They helped undermine Victorian sexual sensibilities, gave courts new forensic tools, provided plots for novels and movies, and offered artists from Picasso to Warhol new ways to depict the human form.