This volume provides the orthopaedic surgeon and resident with a reference on the clinical and radiographic presentation of staging and general approaches to orthopaedic tumors. The coverage includes a discussion on tumor types, formulating a differential diagnosis, interpretation of radiographic findings, and treatment and complications.
Bone Tumors: A Practical Guide to Imaging is a concise guide to common tumors encountered by physicians in daily practice. The authors make use of high-yield facts, differential diagnoses, and extensive radiological images to introduce a wide range of bone tumors, focusing on their classic appearance and location in order to provide readers with a solid foundation of knowledge for tumor recognition and evaluation. The book includes explanations of methods for properly evaluating bone lesions, common imaging modalities used for diagnosis, and individual chapters covering different classes of benign and malignant tumors, including cartilage, osseous, fibrous, miscellaneous, and bone metastases. The book concludes with a comprehensive selection of 75 unknown cases, including brief clinical history, description of imaging findings, best differential diagnoses, and short discussion revealing the most likely diagnosis. Bone Tumors is an ideal resource for practicing physicians and residents in radiology, orthopedic surgery, pathology, and primary care. About the Authors Jim S. Wu, MD, is Assistant Professor of Radiology at Beth Israel Deaconess Medical Center, Harvard Medical School. Mary G. Hochman, MD, is Chief of the Section of Musculoskeletal Imaging and Assistant Professor of Radiology at Beth Israel Deaconess Medical Center, Harvard Medical School.
This book reviews the latest techniques for diagnostics and treatments specific to bone and soft tissue tumors. It focuses on imaging and classification of the bone and soft tissue tumors and how histology and cytogenetic aspects can be used to identify tumors. Each chapter focuses on a specific type of tumor, providing a concise overview of relevant information on their characteristics along with the latest surgical and medical treatments available. Bone Tumors: Diagnosis and Therapy Today is a concise guide to successfully identifying and treating bone and soft tissue tumors, making it a valuable resource for practicing medical professionals and trainees who encounter these patients in their day-to-day practice.
We welcome the publication of this volume, which discusses the diagnosis of bone tumours with particular reference to children and adolescents. As founder members of the International Skeletal Society we are delighted to learn that the book had its inception at one of the Society's meetings. It reflects, moreover, the combined presentation of radiological and pathological diagnostic information which has been such a feature of the meetings of the International Skeletal Society. We commend it to all readers with an interest in tumours of the skeleton. Hubert A. Sissons Ronald O. Murray Preface The diagnosis of primary bone tumors is often difficult. There are several reasons for this. As primary bone tumors are rare in childhood, practitioners in a number of pediatric subspecialties are not familiar with them. The clinical symptoms and signs are often elusive, the biochemical investigations usually normal and the radio graphic features often uncharacteristic. Even the pathologist, who is the final step in arriving at the proper diagnosis and who has all the available clinical, biochemical and radiographic data, may encounter difficulties. A good tissue sample is the basis for microscopic investigation. However, bone tumors often show an extreme variety of structures which confuse even experienced bone pathologists. Therefore, histo pathologic analysis must take into account all available clinical, biochemical and radiographic data. The close cooperation of the pathologist with clinicians and, especially, radiologists is of the utmost importance.
Bone Cancer, Second Edition comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches. The Second Edition expands on the original overview of bone cancer development (physiology and pathophysiology), with key chapters from the first edition, and offers numerous new chapters describing the new concepts of bone cancer biology and therapy, for both primary bone tumors as well as bone metastases. Each chapter has been written by internationally recognized specialists on the bone cancer microenvironment, bone metastases, osteoclast biology in bone cancer, proteomics, bone niche, circulating tumor cells, and clinical trials. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for everyone within the medical and cancer research communities. Bone Cancer continues to offer the only translational reference to cover all aspects of primary bone cancer and bone metastases – from bench to bedside: development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. - Presents a comprehensive, translational source for all aspects of primary bone cancer and bone metastases in one reference work - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Offers insights to research clinicians (oncologists and radiologists) into understanding the molecular basis of bone cancer, leading to more well-informed diagnoses and treatment of tumors and metastases - Offers insights to bone biologists into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays
Visual Guide to Musculoskeletal Tumors: A Clinical-Radiologic-Histologic Approach, by Felasfa Wodajo, MD; Frank Gannon, MD and Mark Murphey, MD, uses a pattern-recognition approach to help you diagnose challenging musculoskeletal tumors with confidence. With an easy-to-use format, it is the only resource that correlates histology studies and imaging studies. By comparing images these superb-quality, large-scale images, you can master pattern recognition for the 30 most important musculoskeletal tumors and make informed, effective, and rapid decisions on diagnosis and treatment. Master pattern recognition and diagnosis of musculoskeletal tumors with easy-to-use templated chapters and 900 illustrations summarizing essential clinical, histologic, and radiologic findings. Make rapid, confident decisions on diagnosis and treatment by comparing your clinical findings to the book’s extensive collection of detailed, large-scale illustrations.
A quick-reference handbook with more than 100 figures, charts, and images, Handbook of Musculoskeletal Tumors provides a wide-ranging overview of musculoskeletal tumors for the practicing clinician. From a pathological fracture in the emergency department to a soft tissue tumor in the clinic, musculoskeletal tumors present in clinical practice yet receive minimal exposure in training. Edited by Drs. Matthew T. Wallace and Frank J. Frassica, Handbook of Musculoskeletal Tumors provides readers with concise recommendations for their encounters with diseases including: Latent bone lesions and active and aggressive benign bone lesions Osteosarcoma, Ewing sarcoma, and primary lymphoma of bone Myeloma and metastatic bone disease, chondrosarcoma, osteochondroma, multiple hereditary exostoses, Ollier disease, and Mafucci syndrome Benign soft tissue tumors, including lipomatous tumors, nerve sheath tumors, and myxoid, fibrous, and vascular lesions Soft tissue sarcomas, including undifferentiated pleomorphic sarcoma, liposarcomas, synovial sarcoma, rhabdomyosarcoma, and epithelioid sarcoma Anatomic-specific considerations, including intra-articular lesions and hand, foot, and spine tumors Written for primary care providers, practicing orthopedists and surgeons, residents and students in training, physician assistants, and nurses and nurse practitioners, Handbook of Musculoskeletal Tumors is a practical guide to help practitioners recognize and diagnose suspicious lesions, order appropriate testing, and facilitate prompt referrals to trained musculoskeletal oncologists when appropriate for additional management. Included with the text are online supplemental materials for faculty use in the classroom.
This book is the second in a two-volume set that offers comprehensive guidance on the diagnosis of bone tumors based on a modification of the WHO classification as well as management and follow-up. The emphasis throughout is on an integrated approach to diagnosis that highlights the role of clinical, radiologic, and pathologic correlation in reducing the possibility of diagnostic error. The diagnosis of bone tumors is difficult for a variety of reasons, including the numerous types of the tumors with variable subtypes, the protean radiologic manifestations and the variable pathologic findings case by case and even depending on the phase in each case, the presence of reactive changes to the tumor lesion, and overlapping findings between benign and malignant tumors. In addition, it is often more difficult by surgeon’s inadequate biopsy. The author’s aim is to offer the readers the best possible guidance in negotiating these difficulties. For each tumor types, a wide range of cases are presented, from the common to the very rare. Appearances on the full range of imaging studies are illustrated, including conventional radiographs, bone scans, CT scan, MRI, and even PET/CT scans in malignant cases. Attention is also drawn to the role of long-term follow-up radiographs in ensuring correct diagnosis and management. This book will be an ideal resource for all practitioners and researchers who involved in bone tumor diagnosis and also management. Volume 2 covers osteoclastic giant cell-rich tumors, hematopoietic tumors, notochordal tumors, cysts and cyst-like lesions, vascular and neurogenic tumors, and tumors of other mesenchymal cells.
The second edition of Dorfman and Czerniak's Bone Tumors brings together the latest data available on bone tumor pathology, making it the most comprehensive and encyclopedic reference on the epidemiology, clinical, pathologic, and molecular aspects of bone tumors. Now offered in full color and featuring updated imaging throughout, this one-of-a-kind resource provides a highly visual review of every disorder — from the common to the rare. Features comprehensive coverage of bone tumor pathology based on pathologic and clinical data on 11,500 benign and malignant bone tumors from patients treated at the MD Anderson Cancer Center. High-quality full-color images located throughout the text. Completely up-to-date molecular and genetic information is based on the most current genomic databases. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and images from the book on a variety of devices. Four brand-new chapters cover Radiographic Imaging of Bone Tumors; Hematopoetic Tumors; Neural Tumors; and Metastic Tumors of Bone. Includes information on molecular and genetic aspects of bone tumors from the UCSC Genome Browser, the Catalog of Somatic Mutations in Cancer, and the GeneCards Database of human genes. Features comprehensive data from nearly 30,000 benign and malignant primary bone tumors and tumor-like lesions from different sources, including over 8,400 malignant bone tumors from the National Cancer Institute’s Surveillance, Epidemiology and End Result project. Provides an enhanced visual understanding with updated radiographic imaging and new full-color, high-quality photomicrographs. Updated Molecular and Epidemiologic diagrams added to all new chapters.
This comprehensive 2nd Edition authoritatively describes bone tumors and non-neoplastic bone conditions commonly encountered in practice. Each chapter deals with a major bone tumor, discussing its diagnosis, clinical presentation, roentgenographic findings, histopathology, and treatment. Particular emphasis is placed on lesions of the craniofacial bones, their diagnosis, treatment, and prognosis.
