Handbook of Computational Molecular Biology

Handbook of Computational Molecular Biology

Author: Srinivas Aluru

Publisher: Chapman and Hall/CRC

Published: 2005-12-21

Total Pages: 1104

ISBN-13: 9781584884064

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The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology offers comprehensive, systematic coverage of the various techniques and methodologies currently available. Accomplished researcher Srinivas Aluru leads a team of experts from around the world to produce this groundbreaking, authoritative reference. With discussions ranging from fundamental concepts to practical applications, this book details the algorithms necessary to solve novel problems and manage the massive amounts of data housed in biological databases throughout the world. Divided into eight sections for convenient searching, the handbook covers methods and algorithms for sequence alignment, string data structures, sequence assembly and clustering, genome-scale computational methods in comparative genomics, evolutionary and phylogenetic trees, microarrays and gene expression analysis, computational methods in structural biology, and bioinformatics databases and data mining. The Handbook of Computational Molecular Biology is the first resource to integrate coverage of the broad spectrum of topics in computational biology and bioinformatics. It supplies a quick-reference guide for easy implementation and provides a strong foundation for future discoveries in the field.


Computational Molecular Evolution

Computational Molecular Evolution

Author: Ziheng Yang

Publisher: Oxford University Press, USA

Published: 2006-10-05

Total Pages: 374

ISBN-13: 0198566999

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This book describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes.


A Bibliography on Computational Molecular Biology and Genetics

A Bibliography on Computational Molecular Biology and Genetics

Author: Sarah Barron

Publisher: DIANE Publishing

Published: 1991

Total Pages: 122

ISBN-13: 9780941375917

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Provides a definitive bibliographic review of the literature related to DNA mapping and sequence analysis, with a focus on computer and mathematical aspects of molecular biology and genetics. Over 2200 entries, arranged by author's name.


Introduction to Computational Biology

Introduction to Computational Biology

Author: Michael S. Waterman

Publisher: CRC Press

Published: 2018-05-02

Total Pages: 456

ISBN-13: 1351437089

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Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.


Fundamentals of Bioinformatics and Computational Biology

Fundamentals of Bioinformatics and Computational Biology

Author: Gautam B. Singh

Publisher: Springer

Published: 2014-09-24

Total Pages: 345

ISBN-13: 3319114034

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This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolboxTM. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.


Bioinformatics And Genome Research - Proceedings Of The Third International Conference

Bioinformatics And Genome Research - Proceedings Of The Third International Conference

Author: Hwa A Lim

Publisher: World Scientific

Published: 1995-09-20

Total Pages: 560

ISBN-13: 9814548715

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This book is a collection of talks presented at the Third International Conference on Bioinformatics and Genome Research, June 1-4, 1994, at Tallahassee Conference Center. Topics include: database management, genome rearrangement, molecular informatics of HIV, gene regulation and metabolism, nucleic and protein sequence research, understanding of genetic data through graphic displays, tools and techniques for genome analyses and a panel discussion of technology transfer.


Analyzing Network Data in Biology and Medicine

Analyzing Network Data in Biology and Medicine

Author: Nataša Pržulj

Publisher: Cambridge University Press

Published: 2019-03-28

Total Pages: 647

ISBN-13: 1108432239

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Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.


Algorithms in Computational Molecular Biology

Algorithms in Computational Molecular Biology

Author: Mourad Elloumi

Publisher: John Wiley & Sons

Published: 2011-04-04

Total Pages: 1027

ISBN-13: 1118101987

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This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.