Targeted Therapies in Oncology

Targeted Therapies in Oncology

Author: Giuseppe Giaccone

Publisher: CRC Press

Published: 2007-09-25

Total Pages: 426

ISBN-13: 1420020587

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Targeted therapy is one of the most burgeoning areas of development in cancer research. Increasing knowledge in tumor formation and growth at the molecular level has generated a broad array of therapeutic options, including signal transduction inhibition, anti-angiogenic and anti-vascular agents, cell cycle inhibitors, telomerase and telomere inter


Handbook of Therapeutic Antibodies

Handbook of Therapeutic Antibodies

Author: Stefan Dübel

Publisher: John Wiley & Sons

Published: 2014-12-03

Total Pages: 2538

ISBN-13: 3527329374

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Dieses Nachschlagewerk zu therapeutischen Antikörpern sucht auch in der komplett überarbeiteten 2. Auflage seinesgleichen und bietet 30 % neue Inhalte zu Entwicklung, Herstellung und therapeutischen Anwendungen dieser Biomoleküle.


Perez and Brady's Principles and Practice of Radiation Oncology

Perez and Brady's Principles and Practice of Radiation Oncology

Author: Edward C. Halperin

Publisher: Lippincott Williams & Wilkins

Published: 2008

Total Pages: 2152

ISBN-13: 9780781763691

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The thoroughly updated fifth edition of this landmark work has been extensively revised to better represent the rapidly changing field of radiation oncology and to provide an understanding of the many aspects of radiation oncology. This edition places greater emphasis on use of radiation treatment in palliative and supportive care as well as therapy.


Anticancer Treatments and Cardiotoxicity

Anticancer Treatments and Cardiotoxicity

Author: Patrizio Lancellotti

Publisher: Academic Press

Published: 2016-11-11

Total Pages: 483

ISBN-13: 0128026472

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Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. - Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients - Written by world-leading experts in the field of cardiotoxicity - Includes high-quality images, case studies, and test questions - Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment


An Introduction to the Use of Anticancer Drugs

An Introduction to the Use of Anticancer Drugs

Author: Imran Rafi

Publisher: Elsevier Health Sciences

Published: 2006-01-01

Total Pages: 222

ISBN-13: 0750688300

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This title is directed primarily towards health care professionals outside of the United States. The aim of this book is to provide an introduction to the principles of drug treatment for solid tumours in cancer medicine. Developments in the understanding of tumour biology, molecular biology and genetics - together with the greater understanding of the pharmacology and pharmacokinetics of drugs - have combined to open up the field of medical oncology to rapid advances in the treatment of cancers. The range of drugs that are available is wide and one of the primary aims in drug development is to increase the therapeutic window so that drug toxicity is minimised and tolerable. Drug development of oral formulations of anticancer drugs and the use of drugs that could be given in the day patient setting means that healthcare professionals such as general practitioners - who historically might not have been involved in the drug treatment of the cancer patient - are now going to need to have a greater understanding of the principles of use of anticancer drugs. This book is primarily aimed at this market. Basic principles of drug treatment - develops an understanding of why and when anticancer drugs are used. Covers the purpose of clinical trials in oncology from Phase I to Phase IV trials in drug development. Discusses the organisation of clinical networks in the UK. Case studies in cancer treatment, allowing an understanding of when and why the typical regimes are used. NICE guidelines.


Accelerated Partial Breast Irradiation

Accelerated Partial Breast Irradiation

Author: David E. Wazer

Publisher: Springer Science & Business Media

Published: 2006-08-02

Total Pages: 275

ISBN-13: 3540282033

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This text is a concise handbook designed to assist the clinician in the implementation of Accelerated Partial Breast Irradiation (APBI). It includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications. The book encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation.