Biomaterials and Medical Devices

Biomaterials and Medical Devices

Author: Ferdyansyah Mahyudin

Publisher: Springer

Published: 2016-02-26

Total Pages: 249

ISBN-13: 3319148451

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This book presents an introduction to biomaterials with the focus on the current development and future direction of biomaterials and medical devices research and development in Indonesia. It is the first biomaterials book written by selected academic and clinical experts experts on biomaterials and medical devices from various institutions and industries in Indonesia. It serves as a reference source for researchers starting new projects, for companies developing and marketing products and for governments setting new policies. Chapter one covers the fundamentals of biomaterials, types of biomaterials, their structures and properties and the relationship between them. Chapter two discusses unconventional processing of biomaterials including nano-hybrid organic-inorganic biomaterials. Chapter three addresses biocompatibility issues including in vitro cytotoxicity, genotoxicity, in vitro cell models, biocompatibility data and its related failure. Chapter four describes degradable biomaterial for medical implants, which include biodegradable polymers, biodegradable metals, degradation assessment techniques and future directions. Chapter five focuses on animal models for biomaterial research, ethics, care and use, implantation study and monitoring and studies on medical implants in animals in Indonesia. Chapter six covers biomimetic bioceramics, natural-based biocomposites and the latest research on natural-based biomaterials in Indonesia. Chapter seven describes recent advances in natural biomaterial from human and animal tissue, its processing and applications. Chapter eight discusses orthopedic applications of biomaterials focusing on most common problems in Indonesia, and surgical intervention and implants. Chapter nine describes biomaterials in dentistry and their development in Indonesia.


Scientific Advances in STEM

Scientific Advances in STEM

Author: Yadir Torres

Publisher: Mdpi AG

Published: 2021-09-10

Total Pages: 362

ISBN-13: 9783036517759

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This book collects the publications of the special Topic Scientific advances in STEM: from Professor to students. The aim is to contribute to the advancement of the Science and Engineering fields and their impact on the industrial sector, which requires a multidisciplinary approach. University generates and transmits knowledge to serve society. Social demands continuously evolve, mainly because of cultural, scientific, and technological development. Researchers must contextualize the subjects they investigate to their application to the local industry and community organizations, frequently using a multidisciplinary point of view, to enhance the progress in a wide variety of fields (aeronautics, automotive, biomedical, electrical and renewable energy, communications, environmental, electronic components, etc.). Most investigations in the fields of science and engineering require the work of multidisciplinary teams, representing a stockpile of research projects in different stages (final year projects, master's or doctoral studies). In this context, this Topic offers a framework for integrating interdisciplinary research, drawing together experimental and theoretical contributions in a wide variety of fields.


Structure—Property Relationships in Polymers

Structure—Property Relationships in Polymers

Author: Charles E. Carraher Jr.

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 234

ISBN-13: 1468447483

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The first concern of scientists who are interested in synthetic polymers has always been, and still is: How are they synthesized? But right after this comes the question: What have I made, and for what is it good? This leads to the important topic of the structure-property relations to which this book is devoted. Polymers are very large and very complicated systems; their character ization has to begin with the chemical composition, configuration, and con formation of the individual molecule. The first chapter is devoted to this broad objective. The immediate physical consequences, discussed in the second chapter, form the basis for the physical nature of polymers: the supermolecular interactions and arrangements of the individual macromolecules. The third chapter deals with the important question: How are these chemical and physical structures experimentally determined? The existing methods for polymer characterization are enumerated and discussed in this chapter. The following chapters go into more detail. For most applications-textiles, films, molded or extruded objects of all kinds-the mechanical and the thermal behaviors of polymers are of pre ponderant importance, followed by optical and electric properties. Chapters 4 through 9 describe how such properties are rooted in and dependent on the chemical structure. More-detailed considerations are given to certain particularly important and critical properties such as the solubility and permeability of polymeric systems. Macromolecules are not always the final goal of the chemist-they may act as intermediates, reactants, or catalysts. This topic is presented in Chapters 10 and 11.


Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author: Jorge Coelho

Publisher: Springer Science & Business Media

Published: 2013-03-15

Total Pages: 433

ISBN-13: 9400760108

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This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.


Biomedical Applications of Functionalized Nanomaterials

Biomedical Applications of Functionalized Nanomaterials

Author: Bruno Filipe Carmelino Cardoso Sarmento

Publisher: Elsevier

Published: 2018-03-03

Total Pages: 0

ISBN-13: 9780323508780

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Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies.


Tomorrow's Medicine

Tomorrow's Medicine

Author: Scientific American Editors

Publisher: Scientific American

Published: 2014-04-28

Total Pages: 227

ISBN-13: 1466858877

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One hundred years ago, most of the medical treatments and technologies that we take for granted hadn't even been imagined or were found in the pages of science fiction novels rather than medical journals. Today, on the other hand, medical research often sounds like science fiction. This eBook, Tomorrow's Medicine, looks at some of the more fascinating areas where technology that could transform health is being developed, including cybernetics, regenerative medicine, nanotechnology and genetically tailored treatments. Although many of these advances may not be ready to treat humans for many years, some of them may someday profoundly change—and extend—our lives. In "Bionic Connections," for example, D. Kacy Cullen and Douglas Smith discuss synthetic limbs that function as well (or better) than our own. Echoes of the 1966 film Fantastic Voyage abound in "Nanomedicine Targets Cancer" by James Heath, Mark Davis and Leroy Hood, who examine how miniaturized tools can both measure the molecular interactions of disease and deliver targeted therapies. Several articles discuss different approaches for regeneration, including "Grow Your Own Eye," in which author Yoshiki Sasai illustrates how his lab successfully grew a retina from stem cells to "A Sweet Solution for Replacing Organs," in which Katherine Harmon describes how a speaker at a recent TED talk used a 3-D printer to create a kidney. A century from now, will the sight of an amputee be a rarity, with cybernetic limbs controlled by thought and nearly indistinguishable from the biological ones? Perhaps most people will have their genomes read for indications of future disease and take steps to prevent it – or even to cure inherited disorders. Will we replace some drugs with tiny machines, fanning out inside the body to repair damage? As exciting as these possibilities are to extend both the length and quality of life, immortality – or at least agelessness – may be forever out of our reach. As Thomas Kirkwood notes in his piece, "Why Can't We Live Forever?" death might be the price we pay for our complex biology. Even so, the doctors of a century past would surely be impressed by what medical science has accomplished in the past hundred years: antibiotics, organ transplants and the elimination of smallpox, to name but a few. The next century should be equally impressive, and with the various types of new technologies on the horizon, many of us have a good chance of seeing it happen.


Oligonucleotide-Based Therapies

Oligonucleotide-Based Therapies

Author: Olof Gissberg

Publisher: Humana

Published: 2020-08-15

Total Pages: 344

ISBN-13: 9781493996728

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This book provides a collection of comprehensive, up-to-date, and broadly applicable guides to the research and development fields of oligonucleotide (ON) therapeutics. Covering topics from the study of antisense and anti-gene effects to oligonucleotides in the context of drug discovery and development, the volume explores a wide-ranging and useful spectrum of methods and protocols needed to take full advantage of therapeutic applications involving ONs. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Oligonucleotide-Based Therapies: Methods and Protocols aims to be a great aid in the laboratory as well as an ideal reference guide when designing antisense and anti-gene oligonucleotides for therapeutic applications.


Biomedical Polymers

Biomedical Polymers

Author: Mike Jenkins

Publisher: CRC Press

Published: 2007-09-10

Total Pages: 244

ISBN-13:

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A review of the latest research on biomedical polymers, this book discusses natural, synthetic, biodegradable and non bio-degradable polymers and their applications. Chapters discuss polymeric scaffolds for tissue engineering and drug delivery systems, the use of polymers in cell encapsulation, their role as replacement materials for heart valves and arteries, and their applications in joint replacement. The book also discusses the use of polymers in biosensor applications. Edited by an expert team of reasearchers and containing contributions from pioneers throughout the field, the book is an essential reference for scientists and all those developing and using this important group of biomaterials.