125 Years of DNA.
Author:
Publisher:
Published: 1994
Total Pages: 58
ISBN-13:
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The Evaluation of Forensic DNA Evidence
Author: National Research Council
Publisher: National Academies Press
Published: 1996-12-12
Total Pages: 270
ISBN-13: 0309134404
DOWNLOAD EBOOKIn 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
The Social Life of DNA
Author: Alondra Nelson
Publisher: Beacon Press
Published: 2016
Total Pages: 218
ISBN-13: 0807033014
DOWNLOAD EBOOKThe unexpected story of how genetic testing is affecting race in America We know DNA is a master key that unlocks medical and forensic secrets, but its genealogical life is both revelatory and endlessly fascinating. Tracing genealogy is now the second-most popular hobby amongst Americans, as well as the second-most visited online category. This billion-dollar industry has spawned popular television shows, websites, and Internet communities, and a booming heritage tourism circuit. The tsunami of interest in genetic ancestry tracing from the African American community has been especially overwhelming. In The Social Life of DNA, Alondra Nelson takes us on an unprecedented journey into how the double helix has wound its way into the heart of the most urgent contemporary social issues around race. For over a decade, Nelson has deeply studied this phenomenon. Artfully weaving together keenly observed interactions with root-seekers alongside illuminating historical details and revealing personal narrative, she shows that genetic genealogy is a new tool for addressing old and enduring issues. In The Social Life of DNA, she explains how these cutting-edge DNA-based techniques are being used in myriad ways, including grappling with the unfinished business of slavery: to foster reconciliation, to establish ties with African ancestral homelands, to rethink and sometimes alter citizenship, and to make legal claims for slavery reparations specifically based on ancestry. Nelson incisively shows that DNA is a portal to the past that yields insight for the present and future, shining a light on social traumas and historical injustices that still resonate today. Science can be a crucial ally to activism to spur social change and transform twenty-first-century racial politics. But Nelson warns her readers to be discerning: for the social repair we seek can't be found in even the most sophisticated science. Engrossing and highly original, The Social Life of DNA is a must-read for anyone interested in race, science, history and how our reckoning with the past may help us to chart a more just course for tomorrow.
Fundamentals of Forensic DNA Typing
Author: John M. Butler
Publisher: Academic Press
Published: 2009-09-30
Total Pages: 519
ISBN-13: 0080961762
DOWNLOAD EBOOKFundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key
50 Years of DNA
Author: J. Clayton
Publisher: Springer
Published: 2016-04-30
Total Pages: 145
ISBN-13: 1137117818
DOWNLOAD EBOOKCrick and Watson's discovery of the structure of DNA fifty years ago marked one of the great turning points in the history of science. Biology, immunology, medicine and genetics have all been radically transformed in the succeeding half-century, and the double helix has become an icon of our times. This fascinating exploration of a scientific phenomenon provides a lucid and engaging account of the background and context for the discovery, its significance and afterlife, while a series of essays by leading scientists, historians and commentators offers uniquely individual perspectives on DNA and its impact on modern science and society.
DNA
Author: James D. Watson
Publisher: Random House
Published: 2004
Total Pages: 546
ISBN-13: 0099451840
DOWNLOAD EBOOKAlong with Frances Crick, James Watson discovered the double-helix structure of the DNA molecule. This book describes the fifty years of explosive scientific achievement that derived from their work, including Dolly the sheep, GM foods & designer babies.
The Lost Family
Author: Libby Copeland
Publisher: Abrams
Published: 2020-03-03
Total Pages: 196
ISBN-13: 1683358937
DOWNLOAD EBOOK“A fascinating exploration of the mysteries ignited by DNA genealogy testing—from the intensely personal and concrete to the existential and unsolvable.” —Tana French, New York Times–bestselling author You swab your cheek or spit in a vial, then send it away to a lab somewhere. Weeks later you get a report that might tell you where your ancestors came from or if you carry certain genetic risks. Or, the report could reveal a long-buried family secret that upends your entire sense of identity. Soon a lark becomes an obsession, a relentless drive to find answers to questions at the core of your being, like “Who am I?” and “Where did I come from?” Welcome to the age of home genetic testing. In The Lost Family, journalist Libby Copeland investigates what happens when we embark on a vast social experiment with little understanding of the ramifications. She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story. Gripping and masterfully told, The Lost Family is a spectacular book on a big, timely subject. “An urgently necessary, powerful book that addresses one of the most complex social and bioethical issues of our time.” —Dani Shapiro, New York Times–bestselling author “Before you spit in that vial, read this book.” —The New York Times Book Review “Impeccably researched . . . up-to-the-minute science meets the philosophy of identity in a poignant, engaging debut.” —Kirkus Reviews (starred review)
The Journey of Man
Author: Spencer Wells
Publisher: Princeton University Press
Published: 2017-03-28
Total Pages: 238
ISBN-13: 0691176019
DOWNLOAD EBOOKAround 60,000 years ago, a man, genetically identical to us, lived in Africa. Every person alive today is descended from him. How did this real-life Adam wind up as the father of us all? What happened to the descendants of other men who lived at the same time? And why, if modern humans share a single prehistoric ancestor, do we come in so many sizes, shapes, and races? Examining the hidden secrets of human evolution in our genetic code, the author reveals how developments in the revolutionary science of population genetics have made it possible to create a family tree for the whole of humanity. Replete with marvelous anecdotes and remarkable information, from the truth about the real Adam and Eve to the way differing racial types emerged, this book is an enthralling, epic tour through the history and development of early humankind.
Building Drexel
Author: Richardson Dilworth
Publisher: Temple University Press
Published: 2016-12-12
Total Pages: 454
ISBN-13: 1439914206
DOWNLOAD EBOOKPublished in conjunction with Drexel University’s 125th anniversary, Building Drexel chronicles the founding of the university by Anthony J. Drexel through to the present day. The editors and contributors create a prismatic discussion of the university and its evolution. Richly illustrated chapters cover the architectural history of notable Drexel buildings; the role of Drexel in Philadelphia’s modern history; its Greek life; sports—particularly Drexel’s history in the Big 5; and each of the university’s schools and colleges. There is a history of the medical college and law school, plus the creation of new schools such as those of biomedical engineering, science and health systems. Building Drexel also documents the civil rights history of Drexel and its urban planning history in relation to the racially diverse Powelton Village and Mantua neighborhoods it borders. This commemorative volume shows the development of the university both in the city and in the world. Contributors include: Lloyd Ackert, Cordelia Frances Biddle, Paula Marantz Cohen, Donna Marie De Carolis, Roger Dennis, Gloria Donnelly, Kevin D. Egan, Alissa Falcone, David Fenske, John A. Fry, Stephen F. Gambescia, Marla J. Gold, Charles Haas, Kathy Harvatt, Daniel Johnson, Jeannine Keefer, Larry Keiser, Michael Kelley, Jason Ludwig, Jonson Miller, Julie Mostov, Danuta A. Nitecki, Anthony M. Noce, Steven J. Peitzman, David Raizman, Tiago Saraiva, Amy E. Slaton, Nathaniel Stanton, Virginia Theerman, Laura Valenti, James Wolfinger, Eric A. Zillmer, and the editors.
Restriction Enzymes
Author: Wil A. M. Loenen
Publisher:
Published: 2019
Total Pages: 346
ISBN-13: 9781621821052
DOWNLOAD EBOOKRestriction enzymes cleave DNA at specific recognition sites and have many uses in molecular biology, genetics, and biotechnology. More than 4000 restriction enzymes are known today, of which more than 621 are commercially available, justifying their description by Nobel Prize winner Richard Roberts as "the workhorses of molecular biology." This book by Wil Loenen is the first full-length history of these invaluable tools, from their recognition in the 1950s to the flowering of their development in the 1970s and 1980s to their ubiquitous availability today. Loenen has worked with restriction enzymes throughout her career as a research scientist, during which she came to know many of the leaders in this field personally and professionally. She is the author of several authoritative and widely appreciated reviews of the enzymes' biology. Her book was written with the close assistance of several of the field's pioneers, including Rich Roberts, Stuart Linn, Tom Bickle, Steve Halford, and the late Joe Bertani. The seed for the book was sown at a retirement party for Noreen Murray, to whom the book is dedicated, and its roots lie in a remarkable 2013 conference at Cold Spring Harbor Laboratory that celebrated the people and events that were vital to the field's development. Funding for the book was made possible by the Genentech Center for the History of Molecular Biology and Biotechnology at Cold Spring Harbor Laboratory.
