Vectorology for Optogenetics and Chemogenetics

Vectorology for Optogenetics and Chemogenetics

Author: Mark A.G. Eldridge

Publisher: Springer Nature

Published: 2023-02-06

Total Pages: 331

ISBN-13: 1071629182

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This volume provides an overview of the viral vectors and how they are applied to chemogenetic and optogenetic tools to the study of neural circuits. The chapters in this book are organized into three parts detailing (1) viral vectors, (2) vector modifications and applications, and (3) practical advice for the delivery of viral vectors, verification of injection accuracy, and monitoring of transgene expression. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Authoritative and cutting-edge, Vectorology for Optogenetics and Chemogenetics aims to be a useful practical guide to researches to help further their study in this field.


Gene Therapy for Neurological Disorders

Gene Therapy for Neurological Disorders

Author: Rishabha Malviya

Publisher: CRC Press

Published: 2024-12-06

Total Pages: 235

ISBN-13: 1040052118

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Neurological illnesses pose one of the biggest hazards to the healthcare system today. This new book brings together the latest methods of gene therapy that can be used to treat both inherited and sporadic neurodegenerative diseases. It presents the most significant advances in gene transfer methods as well as the most recent understandings of the mechanisms behind specific neurodegenerative illnesses, placing these into the context of gene therapy approaches for the central nervous system. The book introduces the basics of neurodegenerative conditions and the physiological basis for their occurrence in humans. It also discusses the various proteins useful in neuro diseases and their viral applications. The book explores how stem cells can be used to learn about the future of gene therapy along with the significance of the sequences that silence genes. It discusses the functions of astrocytes in different brain regions, as well as in-vivo research in gene therapy for neurodegenerative disorders.


Gene Therapy Methods

Gene Therapy Methods

Author: M. Ian Phillips

Publisher: Academic Press

Published: 2002-02-22

Total Pages: 770

ISBN-13: 0121822478

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This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the methods-oriented style popularized by this series. Discusses methods currently used in preclinical and clinical gene therapy Covers the use of adeno-associated virus delivery for treatment of Parkinson's disease


Gene Therapy Protocols

Gene Therapy Protocols

Author: Paul D. Robbins

Publisher: Humana PressInc

Published: 1997

Total Pages: 432

ISBN-13: 9780896034846

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Thirty protocols by leading researchers describe in detail all the essential molecular methods for working with gene transfer systems, along with the methods for gene transfer to specific tissue types either in vivo or ex vivo. The easily reproducible methods range from those for specific viral and nonviral for both genetic and acquired diseases, to those concerned with gene delivery to particular tissues. Methods for applying specific therapeutic systems, such as ribozymes and tumor supressor genes for the treatment of AIDS and cancer, are also included in this authoritative collection.


Conquering Jerusalem

Conquering Jerusalem

Author: Stephen Dando-Collins

Publisher: Turner Publishing Company

Published: 2021-07-13

Total Pages: 237

ISBN-13: 1684425492

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AWARD-WINNING AUTHOR AND HISTORIAN STEPHEN DANDO-COLLINS PROVIDES UNPARALLELED NEW INSIGHT INTO THE FIRST JEWISH REVOLT Dando-Collins details the conflict from both sides of the 7-year campaign. His examination of the revolt draws upon numerous archaeological and forensic discoveries made in recent years to illuminate the people and events as never before. Neither side emerges from the conflict unscathed. Both were at times equally heroic and barbaric. In the end, the Jewish freedom fighters lost the war and lost Jerusalem, their holy city– the focus of the campaign by both sides. Yet today, Jerusalem is once more the heart of the Jewish faith, while, thanks to Christianity–an offshoot of Judaism–the Roman Empire and its gods are long gone. Conquering Jerusalem illustrates that faith can have its rewards, and the tables can be turned, if you wait long enough.


Differential and Integral Equations

Differential and Integral Equations

Author: Peter J. Collins

Publisher: Oxford University Press, USA

Published: 2006-08-03

Total Pages: 387

ISBN-13: 0198533829

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Differential & integral equations involve important mathematical techniques, & as such will be encountered by mathematicians, & physical & social scientists, in their undergraduate courses. This text provides a clear, comprehensive guide to first- & second- order ordinary & partial differential equations.


You on Purpose

You on Purpose

Author: Dr. Stephanie Shackelford

Publisher: Baker Books

Published: 2021-09-28

Total Pages: 272

ISBN-13: 1493405438

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What should I do with my life? Whether you're just starting out on your journey or you've found yourself at a crossroads and feel the need to change direction, each of us wants to know what our purpose is on this earth. We want our work and our lives to have meaning and impact far beyond our immediate context. But how do you know what you were meant to do? And once you know . . . then what? Based solidly in the most up-to-date Barna research, You on Purpose offers you a clear and simple 4-step process for discovering and carrying out your calling with confidence: Define: set your intention for what you want to achieve Discover: dig deep into who and where you are Decide: narrow your choices and zero in on your calling Do: start acting on your calling, one step at a time Each chapter dismantles a common myth about calling, replacing it with truth born from solid, current research. If you long to discover your unique place in the world, this book will help you catch that vision and make a plan to pursue it.


Learning to Consult

Learning to Consult

Author: Rodger Charlton

Publisher: Radcliffe Publishing

Published: 2007

Total Pages: 302

ISBN-13: 9781857758528

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Chapter 11: Bioethics and values in medicine -- Chapter 12: Consultation models -- Chapter 13: Aids to learning -- Chapter 14: CPD, lifelong learning and preparing for examinations -- Chapter 15: Prescribing for common conditions -- Back Cover


A Father's Quest

A Father's Quest

Author: Wayne McColley

Publisher: Christian Faith Publishing, Inc.

Published: 2021-08-06

Total Pages: 594

ISBN-13: 1638446016

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The title of the book, A Father's Quest, was decided on years before I started writing the book. I knew that I would be writing a book from what a medium had told me years before, but I never started it. Maybe I had to have a bad stroke to make it happen. I had prayed for years that my son would get married. Maybe I would have to have a stroke for this to happen too. God works in our lives in a strange way. For years I went to therapy, learning to walk and to work on moving my arm. I quit therapy in March 2018. I had nothing to do, and I became bored for the first time in my life. That was when I started writing. It would take me twenty-seven months to finish. Many of my friends told me to record the book and have someone type it for me, but I wanted to write the book completely by myself. I'm right-handed, and I can finally move my right hand but cannot really use it. I didn't know how to type, but I typed it with one finger on my left hand on a computer. After our daughter Tammy died on January 5, 1997, it became impossible to sleep. During that time, I lived my whole life over again. I went on a six-year quest, trying to prove that Tammy was murdered and to get custody of my granddaughters, Tammy's children. I would fail more than I would succeed. But I had become too stubborn to ever give up. After I had my stroke, many of my friends told me that this story was motivational to them. I hope you enjoy reading my book, A Father's Quest.


Mac & Irene

Mac & Irene

Author: Margot McMahon

Publisher:

Published: 2021-06

Total Pages: 106

ISBN-13: 9781736767702

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Based on the true story of Franklin "Mac" McMahon, Emmy and Peabody Award-winning artist-reporter and filmmaker. In WWII, McMahon was a U.S. Army Air Corps B-17 navigator who survived the Stalag 13 POW camp to return home to Chicago and his sweetheart, Irene. First of a trilogy on McMahon's legendary career.