Unsupervised Feature Extraction Applied to Bioinformatics
Unsupervised Feature Extraction Applied to Bioinformatics

Author: Y-h. Taguchi

Publisher: Springer Nature

Published: 2019-08-23

Total Pages: 329

ISBN-13: 3030224562

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This book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tenor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics. Allows readers to analyze data sets with small samples and many features; Provides a fast algorithm, based upon linear algebra, to analyze big data; Includes several applications to multi-view data analyses, with a focus on bioinformatics.

Unsupervised Feature Extraction Applied to Bioinformatics
Unsupervised Feature Extraction Applied to Bioinformatics

Author: Y-h Taguchi

Publisher:

Published: 2020

Total Pages: 329

ISBN-13: 9783030224578

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This book proposes applications of tensor decomposition to unsupervised feature extraction and feature selection. The author posits that although supervised methods including deep learning have become popular, unsupervised methods have their own advantages. He argues that this is the case because unsupervised methods are easy to learn since tensor decomposition is a conventional linear methodology. This book starts from very basic linear algebra and reaches the cutting edge methodologies applied to difficult situations when there are many features (variables) while only small number of samples are available. The author includes advanced descriptions about tensor decomposition including Tucker decomposition using high order singular value decomposition as well as higher order orthogonal iteration, and train tenor decomposition. The author concludes by showing unsupervised methods and their application to a wide range of topics. Allows readers to analyze data sets with small samples and many features; Provides a fast algorithm, based upon linear algebra, to analyze big data; Includes several applications to multi-view data analyses, with a focus on bioinformatics.

Application Of Omics, Ai And Blockchain In Bioinformatics Research
Application Of Omics, Ai And Blockchain In Bioinformatics Research

Author: Jeffrey J P Tsai

Publisher: World Scientific

Published: 2019-10-14

Total Pages: 207

ISBN-13: 9811203598

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With the increasing availability of omics data and mounting evidence of the usefulness of computational approaches to tackle multi-level data problems in bioinformatics and biomedical research in this post-genomics era, computational biology has been playing an increasingly important role in paving the way as basis for patient-centric healthcare.Two such areas are: (i) implementing AI algorithms supported by biomedical data would deliver significant benefits/improvements towards the goals of precision medicine (ii) blockchain technology will enable medical doctors to securely and privately build personal healthcare records, and identify the right therapeutic treatments and predict the progression of the diseases.A follow-up in the publication of our book Computation Methods with Applications in Bioinformatics Analysis (2017), topics in this volume include: clinical bioinformatics, omics-based data analysis, Artificial Intelligence (AI), blockchain, big data analytics, drug discovery, RNA-seq analysis, tensor decomposition and Boolean network.

Computational Methods With Applications In Bioinformatics Analysis
Computational Methods With Applications In Bioinformatics Analysis

Author: Jeffrey J P Tsai

Publisher: World Scientific

Published: 2017-06-09

Total Pages: 233

ISBN-13: 981320799X

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This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms.The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics.The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.

Data Analytics in Bioinformatics
Data Analytics in Bioinformatics

Author: Rabinarayan Satpathy

Publisher: John Wiley & Sons

Published: 2021-01-20

Total Pages: 433

ISBN-13: 111978560X

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Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

Computational Methods of Feature Selection
Computational Methods of Feature Selection

Author: Huan Liu

Publisher: CRC Press

Published: 2007-10-29

Total Pages: 437

ISBN-13: 1584888792

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Due to increasing demands for dimensionality reduction, research on feature selection has deeply and widely expanded into many fields, including computational statistics, pattern recognition, machine learning, data mining, and knowledge discovery. Highlighting current research issues, Computational Methods of Feature Selection introduces the

Handbook of Machine Learning Applications for Genomics
Handbook of Machine Learning Applications for Genomics

Author: Sanjiban Sekhar Roy

Publisher: Springer Nature

Published: 2022-06-23

Total Pages: 222

ISBN-13: 9811691584

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Currently, machine learning is playing a pivotal role in the progress of genomics. The applications of machine learning are helping all to understand the emerging trends and the future scope of genomics. This book provides comprehensive coverage of machine learning applications such as DNN, CNN, and RNN, for predicting the sequence of DNA and RNA binding proteins, expression of the gene, and splicing control. In addition, the book addresses the effect of multiomics data analysis of cancers using tensor decomposition, machine learning techniques for protein engineering, CNN applications on genomics, challenges of long noncoding RNAs in human disease diagnosis, and how machine learning can be used as a tool to shape the future of medicine. More importantly, it gives a comparative analysis and validates the outcomes of machine learning methods on genomic data to the functional laboratory tests or by formal clinical assessment. The topics of this book will cater interest to academicians, practitioners working in the field of functional genomics, and machine learning. Also, this book shall guide comprehensively the graduate, postgraduates, and Ph.D. scholars working in these fields.

Big Data Analytics in Bioinformatics and Healthcare
Big Data Analytics in Bioinformatics and Healthcare

Author: Wang, Baoying

Publisher: IGI Global

Published: 2014-10-31

Total Pages: 552

ISBN-13: 1466666129

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As technology evolves and electronic data becomes more complex, digital medical record management and analysis becomes a challenge. In order to discover patterns and make relevant predictions based on large data sets, researchers and medical professionals must find new methods to analyze and extract relevant health information. Big Data Analytics in Bioinformatics and Healthcare merges the fields of biology, technology, and medicine in order to present a comprehensive study on the emerging information processing applications necessary in the field of electronic medical record management. Complete with interdisciplinary research resources, this publication is an essential reference source for researchers, practitioners, and students interested in the fields of biological computation, database management, and health information technology, with a special focus on the methodologies and tools to manage massive and complex electronic information.

Supervised and Unsupervised Learning for Data Science
Supervised and Unsupervised Learning for Data Science

Author: Michael W. Berry

Publisher: Springer Nature

Published: 2019-09-04

Total Pages: 191

ISBN-13: 3030224759

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This book covers the state of the art in learning algorithms with an inclusion of semi-supervised methods to provide a broad scope of clustering and classification solutions for big data applications. Case studies and best practices are included along with theoretical models of learning for a comprehensive reference to the field. The book is organized into eight chapters that cover the following topics: discretization, feature extraction and selection, classification, clustering, topic modeling, graph analysis and applications. Practitioners and graduate students can use the volume as an important reference for their current and future research and faculty will find the volume useful for assignments in presenting current approaches to unsupervised and semi-supervised learning in graduate-level seminar courses. The book is based on selected, expanded papers from the Fourth International Conference on Soft Computing in Data Science (2018). Includes new advances in clustering and classification using semi-supervised and unsupervised learning; Address new challenges arising in feature extraction and selection using semi-supervised and unsupervised learning; Features applications from healthcare, engineering, and text/social media mining that exploit techniques from semi-supervised and unsupervised learning.