United States of America Ex Rel. Barkauskas V. Lane
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Published: 1990
Total Pages: 90
ISBN-13:
DOWNLOAD EBOOKRead and Download eBook Full
Author:
Publisher:
Published: 1990
Total Pages: 90
ISBN-13:
DOWNLOAD EBOOKAuthor:
Publisher:
Published: 1989
Total Pages: 726
ISBN-13:
DOWNLOAD EBOOKIncludes: topical index alphabetical case index, federal rules index, and a synopsis section.
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Published: 1998
Total Pages: 734
ISBN-13:
DOWNLOAD EBOOKAuthor: William Domnarski
Publisher: Oxford University Press
Published: 2016
Total Pages: 305
ISBN-13: 0199332312
DOWNLOAD EBOOKThe first biography of Judge Richard Posner, arguably the most prolific jurist and brilliant legal intellectual of our time --
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Published: 1989
Total Pages: 1804
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DOWNLOAD EBOOKAuthor: United States
Publisher:
Published: 1987
Total Pages: 436
ISBN-13:
DOWNLOAD EBOOKAuthor: Roger A. Cunningham
Publisher:
Published: 1984
Total Pages: 1134
ISBN-13:
DOWNLOAD EBOOKAuthor: William C. Clark
Publisher:
Published: 1987-01-01
Total Pages: 70
ISBN-13: 9780914206286
DOWNLOAD EBOOKAuthor: Toshio Nakanishi
Publisher: Springer Nature
Published: 2020-02-28
Total Pages: 374
ISBN-13: 9811511853
DOWNLOAD EBOOKThis open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.
Author: Israel Vlodavsky
Publisher: Springer Nature
Published: 2020-04-09
Total Pages: 871
ISBN-13: 3030345211
DOWNLOAD EBOOKWritten by internationally recognized leaders in Heparanase biology, the book’s eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.