Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery

Author: Dipankar Chattopadhyay

Publisher: Elsevier

Published: 2024-05-08

Total Pages: 674

ISBN-13: 0323993591

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This book covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels; the properties, characterization, chemistry, and fabrication of these hydrogels is detailed, helping the reader to select the most appropriate material and design for the desired application. The book goes on to review applications in ophthalmic drug delivery, covering in vitro and in vivo models, animal models, preclinical testing, patents and more. Stimuli-responsive Hydrogels for Ophthalmic Drug Delivery is a must-have reference for researchers and academics in the fields of materials science, biomaterials, pharmacology and polymer science, with an interest in clinical aspects of hydrogel design and application. - Provides step-by-step coverage for engineering in-situ and stimuli-responsive hydrogels, from design, characterization, and toxicity considerations to fabrication, process optimization, and drug release kinetics - Utilizes an interdisciplinary approach, bringing together authors from pharmacology, polymer science, and medical backgrounds - Details the advantages and challenges of using stimuli-responsive hydrogels for ophthalmic drug delivery, with a focus on clinical translation

Recent Advances and Future Perspectives of Microbial Metabolites
Recent Advances and Future Perspectives of Microbial Metabolites

Author: Surajit De Mandal

Publisher: Elsevier

Published: 2022-10-15

Total Pages: 356

ISBN-13: 0323901131

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Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine sheds new light on various applications of microbial metabolites in the biomedical sector. The purpose of this book is to integrate the latest research advancements on the application of microbial metabolites in the medical industry into a single platform. In 10 chapters, the significance of biomedical applications and future therapeutic applications of microbial metabolites in human health are highlighted. Several chapters are dedicated to the role of microbial metabolites in precision medicine like the impact of the activities of microbial metabolites in antitumor and antidiabetic agents and immunosuppressive activities. It also provides a roadmap for drugs discovery based on antimicrobial products and the effect of microbial metabolites on humans' health and the immune system. The book finalizes with a chapter on the use of microbial metabolites in OMICS technology. Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine targets researchers from both academia and industry, professors, and graduate students from microbiology, molecular biology, biotechnology, and immunology. Highlights various microbial metabolites and their application in the biomedical sector Illustrates the application of microbial metabolites as potential therapeutic agents Convenient for buyers and readers to understand the basics with advanced information of microbial metabolites

Hendee's Physics of Medical Imaging
Hendee's Physics of Medical Imaging

Author: Ehsan Samei

Publisher: John Wiley & Sons

Published: 2019-02-08

Total Pages: 1006

ISBN-13: 1118670965

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An up-to-date edition of the authoritative text on the physics of medical imaging, written in an accessible format The extensively revised fifth edition of Hendee's Medical Imaging Physics, offers a guide to the principles, technologies, and procedures of medical imaging. Comprehensive in scope, the text contains coverage of all aspects of image formation in modern medical imaging modalities including radiography, fluoroscopy, computed tomography, nuclear imaging, magnetic resonance imaging, and ultrasound. Since the publication of the fourth edition, there have been major advances in the techniques and instrumentation used in the ever-changing field of medical imaging. The fifth edition offers a comprehensive reflection of these advances including digital projection imaging techniques, nuclear imaging technologies, new CT and MR imaging methods, and ultrasound applications. The new edition also takes a radical strategy in organization of the content, offering the fundamentals common to most imaging methods in Part I of the book, and application of those fundamentals in specific imaging modalities in Part II. These fundamentals also include notable updates and new content including radiobiology, anatomy and physiology relevant to medical imaging, imaging science, image processing, image display, and information technologies. The book makes an attempt to make complex content in accessible format with limited mathematical formulation. The book is aimed to be accessible by most professionals with lay readers interested in the subject. The book is also designed to be of utility for imaging physicians and residents, medical physics students, and medical physicists and radiologic technologists perpetrating for certification examinations. The revised fifth edition of Hendee's Medical Imaging Physics continues to offer the essential information and insights needed to understand the principles, the technologies, and procedures used in medical imaging.

Problems and Solutions in Medical Physics
Problems and Solutions in Medical Physics

Author: Kwan Hoong Ng

Publisher: CRC Press

Published: 2018-05-20

Total Pages: 163

ISBN-13: 1351006762

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The first in a three-volume set exploring Problems and Solutions in Medical Physics, this volume explores common questions and their solutions in Diagnostic Imaging. This invaluable study guide should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. It contains key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

Proton Therapy Physics, Second Edition
Proton Therapy Physics, Second Edition

Author: Harald Paganetti

Publisher: CRC Press

Published: 2018-11-19

Total Pages: 772

ISBN-13: 1351855751

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Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics. Features: Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering Discusses clinical aspects, such as treatment planning and quality assurance Offers insight on the past, present, and future of proton therapy from a physics perspective

Proton Therapy Physics
Proton Therapy Physics

Author: Harald Paganetti

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 691

ISBN-13: 1439836450

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Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Ethics for Radiation Protection in Medicine
Ethics for Radiation Protection in Medicine

Author: J. F. Malone

Publisher: CRC Press

Published: 2020-06-30

Total Pages: 182

ISBN-13: 9780367570712

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This book surveys existing ethical frameworks for radiological protection and medical practice and provides the latest developments and new protocols in the field.

Therapeutic Nuclear Medicine
Therapeutic Nuclear Medicine

Author: Richard P. Baum

Publisher: Springer

Published: 2014-08-16

Total Pages: 922

ISBN-13: 3540367195

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The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.