Understanding Behavior in Huntington's Disease
Author: Jane S. Paulsen
Publisher:
Published: 1999-01-01
Total Pages: 46
ISBN-13: 9780963773043
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The Neuropathology of Huntington’s Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy
Author: Udo Rüb
Publisher: Springer
Published: 2015-09-29
Total Pages: 154
ISBN-13: 331919285X
DOWNLOAD EBOOKThis monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
A Physician's Guide to the Management of Huntington's Disease
Author: Adam Rosenblatt
Publisher:
Published: 1999-01-01
Total Pages: 85
ISBN-13: 9780963773029
DOWNLOAD EBOOKBehavioral Neurobiology of Huntington's Disease and Parkinson's Disease
Author: Hoa Huu Phuc Nguyen
Publisher: Springer
Published: 2015-05-23
Total Pages: 402
ISBN-13: 366246344X
DOWNLOAD EBOOKMotor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
Learning to Live with Huntington's Disease
Author: Sandy Sulaiman
Publisher: Jessica Kingsley Publishers
Published: 2007
Total Pages: 178
ISBN-13: 1843104873
DOWNLOAD EBOOKHuntington's Disease (HD), is a hereditary illness passed on via a defective gene. This book offers one family's poignant story of coping with the symptoms, the diagnosis and the effects of HD. It also presents the struggles and strengths of the whole family when one member loses their future to a terminal illness.
Juvenile Huntington's Disease
Author: Oliver Quarrell
Publisher: Oxford University Press, USA
Published: 2009-01-08
Total Pages: 222
ISBN-13: 0199236127
DOWNLOAD EBOOKHuntington's disease (HD) is an inherited progressive neurodegenerative disorder. Although onset of HD usually occurs in adulthood, a small percentage of cases develop symptoms before 20 years of age (juvenile-onset Huntington's Disease or JHD). This book summarises, for the first time, the clinical and scientific knowledge available on JHD.
Caregiver's Handbook
Author: DK
Publisher: Penguin
Published: 2013-09-01
Total Pages: 226
ISBN-13: 1465417443
DOWNLOAD EBOOKThe Caregiver's Handbook is a definitive guide to caring for a sick or disabled person of any age. Whether it be adults looking after parents, partners looking after each other, parents looking after children, or young caregivers looking after their parents, the Caregiver's Handbook addresses both the needs of the caregiver, and person who needs care. The Caregiver's Handbook offers emotional support and practical advice on a wide range of topics, enabling individuals to provide the best care possible-whatever the requirements. Everyday concerns, including healthy eating, personal care, and rest and sleep, are addressed alongside topics such as safe movement and handling, choosing the right stability aids, or even how to maneuver a wheelchair for the first time. Features also include a look at how either at the needs of the caregiver, or how the requirement of specific conditions-such as dementia or physical impairment-can affect the way a task can be approached. The Caregiver's Handbook is a comprehensive, compassionate, and indispensable resource that all caregivers will want to have on hand at all times - it is essential reading for anyone caring for someone at home.
Huntington's Disease
Author: Oliver Quarrell
Publisher:
Published: 1999
Total Pages: 164
ISBN-13: 9780192629302
DOWNLOAD EBOOKHuntington's Disease is a genetically inherited condition, the result of severe nerve-cell damage in the brain. Due to the recent identification of the gene involved, and the debilitating nature of the disease, a great many more people are now affected either directly or indirectly (familiesand carers) by this condition. The majority of people develop the disease between the ages of 35 and 55, so for those that are aware of a genetic inheritance, there are enormous problems to confront - should you carry on life as normal? Should you start a family? In this, the first book onHuntington's disease written for sufferers and their families, advice is given on living with this disabling illness. Written as much for carers as for the patients themselves, the book aims to answer some of the questions that both sufferer and carer might have. With the identification of theresponsible gene, genetic counselling is now available for those at risk of developing the disease. Though some may wish not to use these services, the book clearly explains the role of the counsellor, and what help is additionally available from the various patient organisations worldwide.
Marsden's Book of Movement Disorders
Author: Ivan Donaldson
Publisher: Oxford University Press
Published: 2012-03-29
Total Pages: 1512
ISBN-13: 0191502243
DOWNLOAD EBOOKThis book represents the final work of the late Professor C. David Marsden, who was the most influential figure in the field of movement disorders, in terms of his contributions to both research and clinical practice, in the modern era. It was conceived and written by David Marsden and his colleague at the Institute of Neurology, Prof. Ivan Donaldson. It was their intention that this would be the most comprehensive book on movement disorders and also that it would serve as the 'clinical Bible' for the management of these conditions. It provides a masterly survey of the entire topic, which has been made possible only by vast laboratory and bedside experience. Marsden's Book of Movement Disorders covers the full breadth of movement disorders, from the underlying anatomy and understanding of basal ganglia function to the diagnosis and management of specific movement disorders, including the more common conditions such as Parkinson's Disease through to rare, and very rare conditions such as Niemann-Pick disease. Chapters follow a structured format with historical overviews, definitions, clinical features, differential diagnosis, investigations and treatment covered in a structured way. It is extensively illustrated with many original photographs and diagrams of historical significance. Among these illustrations are still images of some original film clips of some of Dr. Marsden's patients published here for the first time. Comprehensively referenced and updated by experts from the Institute of Neurology at Queen Square, this book is a valuable reference for, not just movement disorder specialists and researchers, but also for clinicians who care for patients with movement disorders.
Hyperkinetic Movement Disorders
Author: Alberto Albanese
Publisher: John Wiley & Sons
Published: 2012-03-07
Total Pages: 413
ISBN-13: 1444346164
DOWNLOAD EBOOKHyperkinetic movement disorders comprise a range of diseases characterized by unwanted and uncontrollable, or poorly controllable, involuntary movements. The phenomenology of these disorders is quite variable encompassing chorea, tremor, dystonia, myoclonus, tics, other dyskinesias, jerks and shakes. Discerning the underlying condition can be very difficult given the range and variability of symptoms. But recognizing the phenomenology and understanding the pathophysiology are essential to ensure appropriate treatment. Hyperkinetic Movement Disorders provides a clinical pathway for effective diagnosis and management of these disorders. The stellar international cast of authors distils the evidence so you can apply it into your practice. The judicious use of diagnostic criteria algorithms rating scales management guidelines Provides a robust framework for clear patient management. Throughout the text, QR codes* provide smartphone access to case-study videos of hyperkinetic symptoms. Purchase includes an enhanced Wiley Desktop Edition.* This is an interactive digital version featuring: all text and images in fully searchable form integrated videos of presentations View a sample video: www.wiley.com/go/albanese highlighting and note taking facilities book marking linking to additional references Hyperkinetic Movement Disorders provides you with the essential visual and practical tools you need to effectively diagnose and treat your patients. *Full instructions for using QR codes and for downloading your digital Wiley DeskTop Edition are inside the book.
