J Wave Syndromes
J Wave Syndromes

Author: Charles Antzelevitch

Publisher: Springer

Published: 2016-06-27

Total Pages: 342

ISBN-13: 3319315781

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This book delineates the state of the art of the diagnosis and treatment of J wave syndromes, as well as where future research needs to be directed. It covers basic science, translational and clinical aspects of these syndromes. The authors are leading experts in their respective fields, who have contributed prominently to the literature concerning these topics. J wave syndromes are one of the hottest topics in cardiology today. Cardiac arrhythmias associated with Brugada syndrome (BrS) or an early repolarization (ER) pattern in the inferior or infero-lateral ECG leads are thought to be mechanistically linked to accentuation of transient outward current (Ito)-mediated J waves. Although BrS and ER syndrome (ERS) differ with respect to magnitude and lead location of abnormal J waves, they are thought to represent a continuous spectrum of phenotypic expression termed J wave syndromes. ERS is divided into three subtypes with the most severe, Type 3, displaying an ER pattern globally in the inferior, lateral and right precordial leads. BrS has been linked to mutations in 19 different genes, whereas ERS has been associated with mutations in 7 different genes. There is a great deal of confusion as to how to properly diagnose and treat the J wave syndromes as well as confusion about the underlying mechanisms. The demonstration of successful epicardial ablation of BrS has provided new therapeutic options for the management of this syndrome for which treatment alternatives are currently very limited, particularly in the case of electrical storms caused by otherwise uncontrollable recurrent VT/VF. An early repolarization pattern is observed in 2-5% of the US population. While it is clear that the vast majority of individuals exhibiting an ER pattern are not at risk for sudden cardiac death, the challenge moving forward is to identify those individuals who truly are at risk and to design safe and effective treatments.

Ventricular Arrhythmias
Ventricular Arrhythmias

Author: John M. Miller

Publisher:

Published: 2008

Total Pages: 0

ISBN-13: 9781416062752

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Ventricular arrhythmias cause most cases of sudden cardiac death, which is the leading cause of death in the US. This issue reviews the causes of arrhythmias and the promising new drugs and devices to treat arrhythmias.

Fetal Cardiology
Fetal Cardiology

Author: John Simpson

Publisher: Springer

Published: 2018-10-24

Total Pages: 329

ISBN-13: 3319774611

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This practical book describes a systematic approach to the ultrasound examination of the fetal heart based on accepted screening recommendations. The written content is enhanced by images and videos of both normal and abnormal sonographic findings. Fetal Cardiology: A Practical Approach to Diagnosis and Management goes further than simply describing core screening views. It includes extended views of the fetal heart, the use of Doppler techniques and assessment of fetal cardiac function. “Variants” which can be encountered in practice are described as well as the features of the major groups of cardiac abnormalities and fetal arrhythmias. Because the authors include experienced fetal and paediatric cardiologists, the focus is not only on diagnostic features but also the approach to postnatal care and prognosis. This content is enhanced by inclusion of chapters relating to associated fetal abnormalities, the genetics of congenital heart disease and new imaging modalities such as MRI of the fetal heart. The book equips all those using ultrasound to image the fetus with a clear concise reference to meet the challenge of new guidelines and to expand their knowledge of complementary echocardiographic techniques and management. It details why prenatal recognition of congenital heart disease is being prioritised to allow for parental choice, recognition of associated abnormalities and improvement of postnatal outcome. As such, this book will be important for all professionals, whether they be a cardiologist, fetal medicine specialist, sonographer or midwife.

Pain Management and the Opioid Epidemic
Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Laudato Si
Laudato Si

Author: Pope Francis

Publisher: Our Sunday Visitor

Published: 2015-07-18

Total Pages: 119

ISBN-13: 1612783872

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“In the heart of this world, the Lord of life, who loves us so much, is always present. He does not abandon us, he does not leave us alone, for he has united himself definitively to our earth, and his love constantly impels us to find new ways forward. Praise be to him!” – Pope Francis, Laudato Si’ In his second encyclical, Laudato Si’: On the Care of Our Common Home, Pope Francis draws all Christians into a dialogue with every person on the planet about our common home. We as human beings are united by the concern for our planet, and every living thing that dwells on it, especially the poorest and most vulnerable. Pope Francis’ letter joins the body of the Church’s social and moral teaching, draws on the best scientific research, providing the foundation for “the ethical and spiritual itinerary that follows.” Laudato Si’ outlines: The current state of our “common home” The Gospel message as seen through creation The human causes of the ecological crisis Ecology and the common good Pope Francis’ call to action for each of us Our Sunday Visitor has included discussion questions, making it perfect for individual or group study, leading all Catholics and Christians into a deeper understanding of the importance of this teaching.

Disease Control Priorities, Third Edition (Volume 5)
Disease Control Priorities, Third Edition (Volume 5)

Author: Dorairaj Prabhakaran

Publisher: World Bank Publications

Published: 2017-11-17

Total Pages: 948

ISBN-13: 1464805202

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Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

The Prevention of Sudden Cardiac Death
The Prevention of Sudden Cardiac Death

Author: John B. Kostis

Publisher: Wiley-Liss

Published: 1990-03-19

Total Pages: 328

ISBN-13:

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Presents diagnostic and therapeutic developments in the field of sudden cardiac death (SCD). Epidemiologic data is reviewed with emphasis on identifying risk factors and the relation of coronary heart disease to SCD. The book offers guidelines for pharmacologic and interventional treatment.

Advances in Cardiopulmonary Resuscitation
Advances in Cardiopulmonary Resuscitation

Author: Peter Safar

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 305

ISBN-13: 1461263387

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Since the late 19505, revolutionary devel in and the potential future of emergency opments of basic knowledge, techniques, resuscitation. This meeting was initiated by teaching, and practice of cardiopulmonary james Elam. james jude, owner of the Wolf Creek Lodge (Blairsville, Georgia 30512), acted resuscitation (CPR) have resulted in the saving of uncountable lives from conditions that as host. previously led to certain death. The 1950s The Program Committee invited primarily clinician-scientists from the United States, brought breakthroughs in respiratory resuscita tion, the 1960s, breakthroughs in cardiac solicited synopsis papers and predistributed resuscitation, and the 1970s have begun to the 37 papers selected to the participants. We were spared formal paper presentations and show breakthroughs in resuscitation of the thus could devote ourselves to two full days arrested brain. Mobilization of large-scale public involve of informal, stimulating, provocative discus ment in life-saving efforts is essential. But the sions. This led to cross-fertilization of ideas challenges and opportunities of implementing among individuals with different specialty backgrounds.