Translation Initiation: Cell Biology, High-throughput and Chemical-based Approaches
Translation Initiation: Cell Biology, High-throughput and Chemical-based Approaches

Author:

Publisher: Academic Press

Published: 2007-10-12

Total Pages: 393

ISBN-13: 0080553486

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For over fifty years the Methods in Enzymology series has been the critically aclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume, the third of three on the topic of Translation Initiation includes articles written by leaders in the field.

Evolution of Translational Omics
Evolution of Translational Omics

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2012-09-13

Total Pages: 354

ISBN-13: 0309224187

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Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B
Biophysical, Chemical, and Functional Probes of RNA Structure, Interactions and Folding: Part B

Author: Daniel Herschlag

Publisher: Academic Press

Published: 2009-11-16

Total Pages: 567

ISBN-13: 0123809231

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This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells. - Expert researchers introduce the most advanced technologies and techniques in protein structure and folding - Includes techniques on tiling assays

Laboratory Methods in Enzymology: Cell, Lipid and Carbohydrate
Laboratory Methods in Enzymology: Cell, Lipid and Carbohydrate

Author:

Publisher: Academic Press

Published: 2013-10-30

Total Pages: 408

ISBN-13: 012420094X

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Methods in Enzymology volumes provide an indispensable tool for the researcher. Each volume is carefully written and edited by experts to contain state-of-the-art reviews and step-by-step protocols. In this volume, we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate, complementing the traditional content that is found in past, present and future Methods in Enzymology volumes. - Indispensable tool for the researcher - Carefully written and edited by experts to contain step-by-step protocols - In this volume we have brought together a number of core protocols concentrating on Cell, Lipid and Carbohydrate

Synthetic Biology
Synthetic Biology

Author: Christopher A. Voigt

Publisher: Academic Press

Published: 2011

Total Pages: 734

ISBN-13: 0123850754

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Synthetic biology encompasses a variety of different approaches, methodologies and disciplines and many different definitions exist. This volume covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation.

Computer Methods Part A
Computer Methods Part A

Author:

Publisher: Academic Press

Published: 2009-03-10

Total Pages: 491

ISBN-13: 0080923291

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The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming 'Computer Methods' volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.

Guide to Yeast Genetics and Molecular Biology
Guide to Yeast Genetics and Molecular Biology

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Publisher: Gulf Professional Publishing

Published: 2004-05-14

Total Pages: 961

ISBN-13: 0080575137

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Guide to Yeast Genetics and Molecular Biology presents, for the first time, a comprehensive compilation of the protocols and procedures that have made Saccharomyces cerevisiae such a facile system for all researchers in molecular and cell biology. Whether you are an established yeast biologist or a newcomer to the field, this volume contains all the up-to-date methods you will need to study "Your Favorite Gene" in yeast.Key Features* Basic Methods in Yeast Genetics* Physical and genetic mapping* Making and recovering mutants* Cloning and Recombinant DNA Methods* High-efficiency transformation* Preparation of yeast artificial chromosome vectors* Basic Methods of Cell Biology* Immunomicroscopy* Protein targeting assays* Biochemistry of Gene Expression* Vectors for regulated expression* Isolation of labeled and unlabeled DNA, RNA, and protein

Synthetic Biology, Part A
Synthetic Biology, Part A

Author: Chris Voigt

Publisher: Academic Press

Published: 2011-07-08

Total Pages: 733

ISBN-13: 0123850762

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Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. - Encompasses a variety of different approaches, methodologies and disciplines - Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation

Oxygen Biology and Hypoxia
Oxygen Biology and Hypoxia

Author:

Publisher: Academic Press

Published: 2007-11-08

Total Pages: 592

ISBN-13: 0080554865

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For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of oxygen biology and hypoxia.