Toxicological Profile for DDT/DDD/DDE (Update)
Toxicological Profile for DDT/DDD/DDE (Update)

Author: Obaid Faroon

Publisher: DIANE Publishing

Published: 2010-08

Total Pages: 497

ISBN-13: 1437930670

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DDT is a pesticide that was once widely used to control insects. Both DDD and DDE are breakdown products of DDT. This profile includes: (1) The examination, summary, and interpretation of available toxicologic info. and epidemiologic evaluations on DDT/DDD/DDE to ascertain the levels of significant human exposure for the substance and the associated chronic health effects; (2) A determination of whether adequate info. on the health effects of DDT/DDD/DDE is available to determine levels of exposure that present a significant risk to human health of chronic health effects; and (3) Identification of toxicologic testing needed to identify the types or levels of exposure that may present significant risk of adverse health effects in humans. Illus.

Phthalates and Cumulative Risk Assessment
Phthalates and Cumulative Risk Assessment

Author: National Research Council

Publisher: National Academies Press

Published: 2009-01-19

Total Pages: 208

ISBN-13: 0309128412

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People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Endocrine Disruption and Human Health
Endocrine Disruption and Human Health

Author: Philippa D. Darbre

Publisher: Academic Press

Published: 2015-03-21

Total Pages: 390

ISBN-13: 0128011203

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Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water
Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC Monographs on the Evaluat

Published: 2013

Total Pages: 0

ISBN-13: 9789283213246

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This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Fragrances
Fragrances

Author: Peter J. Frosch

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 222

ISBN-13: 3642803407

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Aromas are an integral part of our civilised society. They are not only used in fine perfumes, but also in numerous other articles with which we have daily contact. Another new development has been the agricultural use of aromas as a "biological weapon" to combat insects and other pests. In the field of dermatology, aromas are today among the most frequent sensitizers and may trigger allergic contact eczemas. This volume presents numerous aspects of the topic for the first time in comprehensive form. In an introduction, the chemistry of frequently used aroma components is described, together with the art of perfume composition that has been refined over the centuries. In a chapter on neuropharmacology, the mechanisms of scent recognition are described in detail.