Cartilage Repair and Regeneration
Cartilage Repair and Regeneration

Author: Alessandro Rozim Zorzi

Publisher: BoD – Books on Demand

Published: 2018-02-14

Total Pages: 230

ISBN-13: 9535137883

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This work is the result of a partnership that began in 2011, when I received for the first time the invitation to be the scientific editor of a book on bone grafting, by the still little publisher known as InTech. Now six years later, InTech has grown and thrived. My respect and warm approval for the quality of the publisher's work only increased. The hyaline cartilage is a tissue that challenges tissue engineering and regenerative medicine because of its avascular nature. In the 11 chapters of this book, the reader will find texts written by researchers working on advanced topics related to basic laboratory research, as well as excellent reviews on the clinical use of currently available therapies.

Bone and Cartilage Regeneration
Bone and Cartilage Regeneration

Author: Phuc Van Pham

Publisher: Springer

Published: 2017-01-24

Total Pages: 316

ISBN-13: 3319401440

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This invaluable resource discusses clinical applications with effects and side-effects of applications of stem cells in bone and cartilage regeneration. Each chapter is contributed by a pre-eminent scientist in the field and covers such topics as skeletal regeneration by mesenchymal stem cells, clinical improvement of mesenchymal stem cell injection in injured cartilage and osteoarthritis, Good manufacturing practice (GMP), minimal critera of stem cells for clinical applications, future directions of the discussed therapies and much more. Bone & Cartilage Regeneration and the other books in the Stem Cells in Clinical Applications series will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering.

Tissue Engineering for Artificial Organs, 2 Volume Set
Tissue Engineering for Artificial Organs, 2 Volume Set

Author: Anwarul Hasan

Publisher: John Wiley & Sons

Published: 2017-06-19

Total Pages: 762

ISBN-13: 3527338632

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A comprehensive overview of the latest achievements, trends, and the current state of the art of this important and rapidly expanding field. Clearly and logically structured, the first part of the book explores the fundamentals of tissue engineering, providing a separate chapter on each of the basic topics, including biomaterials stem cells, biosensors and bioreactors. The second part then follows a more applied approach, discussing various applications of tissue engineering, such as the replacement or repairing of skins, cartilages, livers and blood vessels, to trachea, lungs and cardiac tissues, to musculoskeletal tissue engineering used for bones and ligaments as well as pancreas, kidney and neural tissue engineering for the brain. The book concludes with a look at future technological advances. An invaluable reading for entrants to the field in biomedical engineering as well as expert researchers and developers in industry.

Articular Cartilage Tissue Engineering
Articular Cartilage Tissue Engineering

Author: Kyriacos A. Athanasiou

Publisher: Morgan & Claypool Publishers

Published: 2010

Total Pages: 183

ISBN-13: 1598298755

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Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

Advances in Biomechanics and Tissue Regeneration
Advances in Biomechanics and Tissue Regeneration

Author: Mohamed H. Doweidar

Publisher: Academic Press

Published: 2019-08-13

Total Pages: 436

ISBN-13: 012816610X

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Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics. - Combines new trends in biomechanical modelling and tissue regeneration - Offers a broad scope, covering the entire field of tissue biomechanics - Contains perspectives from engineering, medicine and biology, thus giving a holistic view of the field

Tissue Engineering Using Ceramics and Polymers
Tissue Engineering Using Ceramics and Polymers

Author: Aldo R. Boccaccini

Publisher: Elsevier

Published: 2007-10-31

Total Pages: 625

ISBN-13: 1845693817

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Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. - An innovative and up-to-date reference for professionals and academics - Environmental scanning electron microscopy is discussed - Analyses bone regeneration and specific types of tisue engineering

Stem Cell and Tissue Engineering
Stem Cell and Tissue Engineering

Author: Song Li

Publisher: World Scientific

Published: 2011

Total Pages: 473

ISBN-13: 9814317055

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Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.

Regenerative Medicine and Plastic Surgery
Regenerative Medicine and Plastic Surgery

Author: Dominik Duscher

Publisher: Springer Nature

Published: 2019-11-27

Total Pages: 480

ISBN-13: 3030199622

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This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Cartilage and Osteoarthritis
Cartilage and Osteoarthritis

Author: Massimo Sabatini

Publisher: Springer Science & Business Media

Published: 2008-02-01

Total Pages: 362

ISBN-13: 1592598102

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Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.

Biomedical Hydrogels
Biomedical Hydrogels

Author: Steve Rimmer

Publisher: Elsevier

Published: 2011-02-26

Total Pages: 280

ISBN-13: 0857091387

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Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel's interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians. - Examines the diverse range and use of hydrogels, focusing on processing methods and novel applications - Comprehensive book explores the structure and properties of hydrogels and different fabrication technologies - Covers important areas such as processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products