Therapy Response Imaging in Oncology
Therapy Response Imaging in Oncology

Author: Mizuki Nishino

Publisher: Springer Nature

Published: 2020-01-07

Total Pages: 266

ISBN-13: 3030311716

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This book is a detailed guide to therapy response imaging in cancer patients that fully takes into account the revolutionary progress and paradigm shift in treatment approaches for advanced disease. The opening chapters describe the role of imaging as a “common language” for tumor response evaluation in oncology and address challenges and strategies in the era of precision cancer therapy and cancer immunotherapy. Practical pitfalls are discussed, with emphasis on the importance of approaching cancer as a systemic disease and the need for increased awareness of drug toxicity due to novel therapies. Therapy response imaging in a wide range of cancer types is then comprehensively described and illustrated, using a disease-specific approach. A concluding section focuses on emerging approaches and future directions, including radiomics/radiogenomics, co-clinical imaging, and molecular and functional imaging. Therapy Response Imaging in Oncology will be of high value for radiologists, nuclear medicine physicians, and oncologists. It will also be of interest to cancer care providers and oncology trial investigators.

Imaging Tumor Response to Therapy
Imaging Tumor Response to Therapy

Author: Massimo Aglietta

Publisher: Springer Science & Business Media

Published: 2012-07-16

Total Pages: 165

ISBN-13: 884702613X

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Measurement of solid tumor response to treatment relies mainly on imaging. WHO tumor response criteria and, more recently, RECIST (response evaluation criteria in solid tumors) have provided means to objectively measure tumor response in clinical trials with imaging. These guidelines have been rapidly adopted in clinical practice to monitor patient treatment and for therapy planning. However, relying only on anatomical information is not always sufficient when evaluating new drugs that will reduce a tumor's functionality while preserving its size. Finding more reliable and reproducible measures of tumor response is one of the most important and difficult challenges facing modern radiology as it requires an entirely new approach to imaging. The aim of this book is to address the assessment of response to treatment by adopting a multidisciplinary perspective, just as occurs in real life in a comprehensive cancer center. Oncologists and imaging experts consider two cancer models, locally advanced disease and metastatic disease, jointly exploring both conventional and advanced means of measuring response to standard treatment protocols and new targeted therapies.

Tumor Response Monitoring and Treatment Planning
Tumor Response Monitoring and Treatment Planning

Author: A. Heuck

Publisher: Springer Science & Business Media

Published: 2013-12-11

Total Pages: 745

ISBN-13: 3642486819

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Medical imaging progressed to a standard undreamt of not very many years ago. The advances are due to continuous development of radiological techniques and the introduction of magnetic resonance imaging. With the improved and new methods three-dimensional target volumes for radiation therapy can be defined with hitherto unknown precision. This leads to an improvement in irradiation techniques and, as a consequence, to a higher likelihood of tumor control and a lower risk of normal tissue complications. Besides the improvement in irradiation techniques the new imaging methods may enable great strides in tumor response monitoring, not only in the detection of morphological alterations but also by showing physiological changes in the tumor during and after treatment by means of MRI and PET. This not only leads to better prognostic information but may also allow early evaluation of the response to treatment. It may then be possible to individualize the radiation dose but also the alternative-treatment for non-responders. This is certainly a future direction for radiation oncology.

In Vivo Imaging of Cancer Therapy
In Vivo Imaging of Cancer Therapy

Author: Anthony F. Shields

Publisher: Springer Science & Business Media

Published: 2007-12-06

Total Pages: 343

ISBN-13: 1597453412

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A variety of cutting-edge imaging techniques, including their use for best practice, are addressed in this book. The book also provides examples of results found in both pre-clinical and clinical studies. This comprehensive text covers the entire spectrum of in vivo imaging for oncology. It will aide clinicians at all levels in keeping up with the most cutting-edge techniques.

Imaging Tumor Response to Therapy
Imaging Tumor Response to Therapy

Author: Massimo Aglietta

Publisher: Springer

Published: 2016-05-01

Total Pages: 176

ISBN-13: 9788847039223

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In this book, oncologists and imaging experts together consider conventional and advanced means of measuring response to standard treatment protocols and new targeted therapies, using two cancer models: locally advanced disease and metastatic disease.

Atlas of Clinical PET-CT in Treatment Response Evaluation in Oncology
Atlas of Clinical PET-CT in Treatment Response Evaluation in Oncology

Author: Stefano Fanti

Publisher: Springer Nature

Published: 2021-07-07

Total Pages: 488

ISBN-13: 3030688585

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This atlas is a superb guide to the use of PET-CT for the evaluation of treatment response in oncology patients based on its ability to assess tumor metabolic status. The first part of the book explains the role of PET-CT in response evaluation in different treatment settings. For comparison, overviews of the value and limitations of CT alone, PET alone, and anatomical and functional MRI are included. Guidance is also provided on the reporting of PET-CT scans in post-therapy scenarios. The second part of the book describes and illustrates the use of PET-CT with FDG and other tracers to assess the treatment response of malignancies at different anatomic sites. Featuring a wealth of images, informative case-based discussion, and evidence-based teaching points, these disease-specific chapters clearly demonstrate the key role that PET-CT can play in distinguishing early responders from patients who are non-responders or are resistant to treatment. Prompt and accurate evaluation of treatment response is vital as we enter the era of individualized medicine, and this atlas will persuade readers of the considerable advantages of PET-CT over conventional radiological and clinical methods.

Principles and Practice of Image-Guided Radiation Therapy of Lung Cancer
Principles and Practice of Image-Guided Radiation Therapy of Lung Cancer

Author: Jing Cai

Publisher: CRC Press

Published: 2017-09-18

Total Pages: 396

ISBN-13: 1498736785

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This book gives a comprehensive overview on the use of image-guided radiation therapy (IGRT) in the treatment of lung cancer, covering step-by-step guidelines for clinical implementations, fundamental principles and key technical advances. It covers benefits and limitations of techniques as well as quality and safety issues related to IGRT practice. Addresses imaging simulation, treatment planning, verification, and delivery Discusses important quality assurance issues Describes current methods using specialized machines and technologies Jing Cai, PhD, is an Associate Professor of Radiation Oncology at Duke University Medical Center. Joe Y. Chang, MD, PhD, is Professor in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center in Houston. Fang-Fang Yin, PhD, is Chief of the Division of Radiation Physics, Professor of Radiation Oncology, and Director of the Medical Physics program at Duke University.

Functional Imaging in Oncology
Functional Imaging in Oncology

Author: Antonio Luna

Publisher: Springer

Published: 2014-07-08

Total Pages: 918

ISBN-13: 3642405827

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In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including diffusion MRI, perfusion CT and MRI, dual-energy CT, spectroscopy, dynamic contrast-enhanced ultrasonography, PET, and hybrid modalities. This second volume considers the applications and benefits of these techniques in a wide range of tumor types, including their role in diagnosis, prediction of treatment outcome, and early evaluation of treatment response. Each chapter addresses a specific malignancy and is written by one or more acclaimed experts. The lucid text is complemented by numerous high-quality illustrations that highlight key features and major teaching points.

Cancer Imaging
Cancer Imaging

Author: M. A. Hayat

Publisher: Academic Press

Published: 2007-11-21

Total Pages: 793

ISBN-13: 0080553761

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This second of two volumes on Cancer Imaging covers the three major topics of imaging instrumentation, general imaging applications, and imaging of a number of human cancer types. Where the first volume emphasized lung and breast carcinomas, Volume 2 focuses on prostate, colorectal, ovarian, gastrointestinal, and bone cancers. Although cancer therapy is not the main subject of this series, the crucial role of imaging in selecting the type of therapy and its post-treatment assessment are discussed. The major emphasis in this volume is on cancer imaging; however, differentiation between benign tumors and malignant tumors is also discussed. This volume is sold individually, and Cancer Imaging, Volume 1 [ISBN: 978-0-12-370468-9] sells separately for $189 and also as part of a two volume set [ISBN: 978-0-12-374212-4] for $299. • Concentrates on the application of imaging technology to the diagnosis and prognosis of prostate, colorectal, ovarian, gastrointestinal, and bone cancers• Addresses relationship between radiation dose and image quality • Discusses the role of molecular imaging in identifying changes for the emergence and progression of cancer at the cellular and/or molecular levels

Functional and Molecular Imaging in Oncology, An Issue of Magnetic Resonance Imaging Clinics of North America
Functional and Molecular Imaging in Oncology, An Issue of Magnetic Resonance Imaging Clinics of North America

Author: Antonio Luna

Publisher: Elsevier Health Sciences

Published: 2016-01-19

Total Pages: 313

ISBN-13: 0323416993

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This issue of MRI Clinics of North America focuses on Functional MRI in Oncology. Articles will include: Functional MRI techniques in oncology in the era of personalized medicine, MRI biomarkers and surrogate endpoints in oncology clinical trials, Therapy monitoring with functional MRI, Multiparametric MRI in the assessment of brain tumors, Multiparametric MRI of breast cancer, Functional MRI in chest malignancies, Multiparametric MRI in abdominal malignancies, Assessment of musculoskeletal malignancies with functional MRI, Evaluation of head and neck tumors with functional MRI, Role of multiparametric MRI in malignancies of the urogenital tract, Diffusion-weighted imaging in oncology, Functional MRI in gynecologic cancer, Assessment of angiogenesis with MRI: DCE-MRI and beyond, Imaging of tumor metabolism: MR spectroscopy, and more!