The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease
Author: Claire Perks
Publisher: Frontiers Media SA
Published: 2022-05-17
Total Pages: 98
ISBN-13: 2889761428
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Growth Hormone in Adults
Author: Anders Juul
Publisher: Cambridge University Press
Published: 2000-04-27
Total Pages: 536
ISBN-13: 9780521641883
DOWNLOAD EBOOKThis revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.
Insulin-like Growth Factors and Cancer
Author: Derek LeRoith
Publisher: Springer Science & Business Media
Published: 2011-09-18
Total Pages: 290
ISBN-13: 146140598X
DOWNLOAD EBOOKThe book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.
Insulin-like Growth Factors
Author: Derek LeRoith
Publisher: CRC Press
Published: 1991-05-28
Total Pages: 328
ISBN-13: 9780849357121
DOWNLOAD EBOOKDuring the past decade, the continued interest in insulin-related growth factors has been documented by a plethora of research programs and publications focused on these growth factors. Both molecular and cellular biological techniques have improved and enabled investigators to study the properties of the growth factors in depth. This volume covers the molecular (genetic) aspects of the growth factors, their binding proteins and receptors, as well as those factors affecting their gene transcription and translation. In addition, aspects of the cellular action of these growth factors through their receptors and how this impacts normal cellular function are discussed. The book will provide valuable information for researchers in physiology, biology, endocrinology, and metabolism.
Growth Hormone Deficiency in Adults
Author: Jens O. L. Jørgensen
Publisher: Karger Medical and Scientific Publishers
Published: 2005-01-01
Total Pages: 241
ISBN-13: 3805579926
DOWNLOAD EBOOKIt has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.
Muscle Atrophy
Author: Junjie Xiao
Publisher: Springer
Published: 2018-11-02
Total Pages: 618
ISBN-13: 9811314357
DOWNLOAD EBOOKThe book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases morbidity and mortality worldwide. The book is divided into five parts, the first of which describes the general aspects of muscle atrophy including its characteristics, related economic and health burdens, and the current clinical therapy. Secondly, basic aspects of muscle atrophy including the composition, structure and function of skeletal muscle, muscle changes in response to atrophy, and experimental models are summarized. Thirdly, the book reviews the molecular mechanisms of muscle atrophy, including protein degradation and synthesis pathways, noncoding RNAs, inflammatory signaling, oxidative stress, mitochondria signaling, etc. Fourthly, it highlights the pathophysiological mechanisms of muscle atrophy in aging and disease. The book’s fifth and final part covers the diagnosis, treatment strategies, promising agents and future prospects of muscle atrophy. The book will appeal to a broad readership including scientists, undergraduate and graduate students in medicine and cell biology.
Milk and Milk Products in Human Nutrition
Author: R.A. Clemens
Publisher: Karger Medical and Scientific Publishers
Published: 2011-02-15
Total Pages: 233
ISBN-13: 3805595875
DOWNLOAD EBOOKMilk, the first and for a time only source of nutrition for mammals, influences early growth and development and may provide a foundation for health throughout the entire lifespan. It is therefore mandatory that milk substitutes have a composition which fulfills the same goals and confers as close as possible the overall health benefits of human milk. Moreover, in many populations, milk continues to play a major role in a healthy and balanced diet throughout life: During childhood, pregnancy and adulthood, intake of cow’s milk has important beneficial effects on linear growth, bone development and the risk of developing caries, and it is important in the prevention and treatment of undernutrition in low-income countries.This publication contains the presentations and discussions of the Nestlé Nutrition Institute Workshop held in Marrakech in March 2010. It focuses on three main topics: milk during pregnancy and infancy, milk during childhood in low- and high-income countries, and general aspects of milk in adult nutrition. Together, these contributions cover most aspects of milk during the life cycle in a global perspective, making the publication a comprehensive textbook.
Growth Factors and Wound Healing
Author: Thomas R. Ziegler
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 374
ISBN-13: 1461218764
DOWNLOAD EBOOKThe aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repair. Written and edited by eminent experts in the field, the papers cover the general concepts of wound healing; the role of nutrients; endogenous growth factors; clinical applications of growth hormone and IGF-1 therapy; and clinical applications of peptide growth factors.
Multidisciplinary Approach to Obesity
Author: Andrea Lenzi
Publisher: Springer
Published: 2014-11-18
Total Pages: 346
ISBN-13: 3319090453
DOWNLOAD EBOOKThis book describes in detail the multidisciplinary management of obesity, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical exercise, psychological issues, nutritional strategies, pharmacological options and bariatric surgery. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of obesity, which has rapidly become a major public health problem.
Insulin and IGFs
Author:
Publisher: Academic Press
Published: 2009-03-10
Total Pages: 766
ISBN-13: 0080922155
DOWNLOAD EBOOKFirst published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on insulin and IGFs. - Longest running series published by Academic Press - Contributions by leading international authorities
