The Quintessence of Basic and Clinical Research and Scientific Publishing
The Quintessence of Basic and Clinical Research and Scientific Publishing

Author: Gowraganahalli Jagadeesh

Publisher: Springer

Published: 2024-10-03

Total Pages: 0

ISBN-13: 9789819912865

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The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated intothe text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.

The Quintessence of Basic and Clinical Research and Scientific Publishing
The Quintessence of Basic and Clinical Research and Scientific Publishing

Author: Gowraganahalli Jagadeesh

Publisher: Springer Nature

Published: 2023-11-01

Total Pages: 926

ISBN-13: 9819912849

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The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.

Orofacial Pain and Headache
Orofacial Pain and Headache

Author: Yair Sharav

Publisher: Elsevier Health Sciences

Published: 2008-01-01

Total Pages: 454

ISBN-13: 0723434123

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OROFACIAL PAIN AND HEADACHE is a timely, comprehensive and instructive addition to the pain literature; in particular the important and truly multidisciplinary area of orofacial pain. Based on their extensive clinical experience and a thorough understanding of pain mechanisms specific to the trigeminal system, the editors, Yair Sharav and Rafael Benoliel, have integrated knowledge from the areas of headache and orofacial pain and have succinctly explained common mechanisms involved in the two phenomena, with important implications for pain diagnosis and management. Internationally renowned editors and contributor teamIntegrated approach to the diagnosis and treatment of oral and facial pain syndromes as well as common primary headaches A thorough review of the four majorclinical entities of orofacial pain: acute dental, neurovascular, musculoskeletal and neuropathicComprehensive coverage of the pharmacotherapy of acute and chronic painChapters on the psychological, neurosurgical and otolaryngological aspects of orofacial painAn in depth discussion of facial pain and headaches secondary to medical co-morbiditiesExploration of complementary and alternative methods of pain control including acupuncture, food additives and hypnosis

Essentials of Orthognathic Surgery
Essentials of Orthognathic Surgery

Author: Johan P. Reyneke

Publisher: Quintessence Publishing (IL)

Published: 2010

Total Pages: 0

ISBN-13: 9780867155006

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"This book presents a concise approach to the diagnosis and surgical treatment of patients with dentofacial deformities. In-depth chapters detail the treatment process of patient evaluation, analysis of diagnostic records, development of a visual treatment objective, treatment planning, and surgical management. The most common surgical techniques are featured in step-by-step protocols. Although the basic science of orthognathic surgery remains unchanged, the contents of this book have been updated to reflect the most current interpretation of diagnostic data, including expanded discussions of the rotation of the maxillomandibular complex and anterior open bite dentofacial deformities as well as new sections on distraction osteogenesis and the intraoral vertical mandibular ramus osteotomy. Full-color illustrations and comprehensive case reports complement the text and demonstrate treatment outcomes."--Publisher.

The Puzzle of Orofacial Pain
The Puzzle of Orofacial Pain

Author: Jens Christoph Türp

Publisher: Karger Medical and Scientific Publishers

Published: 2007-01-01

Total Pages: 261

ISBN-13: 3805582706

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Indispensable for an advanced understanding of orofacial pain In recent years, progress in pain research has yielded substantial new insights, and this has profoundly altered our understanding of various orofacial pain conditions. Written by renowned international researchers and clinicians, this state-of-the-art textbook presents recent advances in the understanding of orofacial pain and offers evidence-based management approaches, thus bridging the gap between timely research findings and daily clinical practice. The reader is provided with helpful in-depth information of up-to-date advances in basic research as well as with the present knowledge of the pathophysiology, diagnosis and management of the five most common orofacial pain conditions. In addition, the psychosocial impact of orofacial pain in daily life and future developments are presented. Health care professionals, such as dentists, neurologists, physicians as well as students will find this volume helpful and valuable for an advanced understanding of the diverse orofacial pain conditions and for the improvement of patient care.

Biocompatibility and Performance of Medical Devices
Biocompatibility and Performance of Medical Devices

Author: Jean-Pierre Boutrand

Publisher: Elsevier

Published: 2012-10-26

Total Pages: 557

ISBN-13: 0857096451

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Implant and device manufacturers are increasingly facing the challenge of proving that their products are safe and biocompatible, and that they will perform as expected. Biocompatibility and performance of medical devices provides an essential guide to the performance analysis of these vital devices.Part one introduces the key concepts and challenges faced in relation to biocompatibility in medical devices, with consideration of biological safety evaluation planning and biomechanical and biochemical compatibility in innovative biomaterials. Part two goes on to discuss the evaluation and characterisation of biocompatibility in medical devices. Topics covered include material and chemical characterisation, allowable limits for toxic leachables, in vivo and in vitro testing and blood compatibility assessment. Testing and interpreting medical device performance is the focus of part three, with chapters describing preclinical performance studies for bone, dental and soft tissue implants, and mechanical testing of soft and hard tissue implants. Part four provides information on the regulation of medical devices in the European Union, Japan and China, and the book concludes with part five, a review of histopathology principles for biocompatibility and performance studies.With its distinguished editor and international team of expert contributors, Biocompatibility and performance of medical devices is a vital tool for all those involved in the research, design, production and application of medical devices, including research directors, production companies and medical regulatory agencies, as well as industry professionals and academics. - Examines the key concepts and challenges faced in relation to biocompatibility in medical devices - Discusses evaluation and characterisation issues, including material and chemical characterization, allowable limits for toxic leachables, in vivo and in vitro testing, and blood compatibility assessment - Delivers a comprehensive overview of testing and interpreting medical device performance

Oral and Maxillofacial Surgery
Oral and Maxillofacial Surgery

Author: Lars Andersson

Publisher: John Wiley & Sons

Published: 2010-09-07

Total Pages: 1316

ISBN-13: 1405171197

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Oral and Maxillofacial Surgery Oral and Maxillofacial Surgery Edited by Lars Andersson, Karl-Erik Kahnberg and M. Anthony Pogrel Oral and Maxillofacial Surgery is a comprehensive reference for all trainees and specialists in oral and maxillofacial surgery, oral surgery, and surgical dentistry. This landmark new resource draws together current research, practice and developments in the field, as expressed by world authorities. The book’s aim is to cover the full scope of oral and maxillofacial surgery, incorporating recent technical and biological developments within the specialty. It provides a uniquely international and contemporary approach, reflecting the exciting developments of technique and instrumentation within this surgical field, built on technical innovation and medical and dental research. Oral and Maxillofacial Surgery coalesces impressively broad and deep coverage of this surgical specialty into a cohesive and readable resource, identifying commonalities and shedding light on controversies through reasoned discussion and balanced presentation of the evidence. The Editors are joined by over 50 international experts, offering a truly global perspective on the full spectrum of issues in oral and maxillofacial surgery. The book’s coverage extends from basic principles such as patient evaluation, dental anesthesia, wound healing, infection control, and surgical instruments, to coverage of the complex areas of dentoalveolar surgery, oral pathologic lesions, trauma, implant surgery, dentofacial deformities, temporomandibular joint disorders, and salivary gland disorders. Where relevant, the book provides separate coverage of topics where practice differs significantly from region to region, such as general anesthesia. Comprehensive reference covering full scope of oral and maxillofacial surgery Covers state-of-art clinical practice, and the basic principles that underpin it Promotes an intellectually and internationally inclusive approach to oral and maxillofacial surgery Nearly 100 expert contributors brought together under the aegis of a renowned international editorial team Richly illustrated with medical artwork and clinical images ALSO OF INTEREST Clinical Periodontology and Implant Dentistry, Fifth Edition Edited by Jan Lindhe, Niklaus P. Lang, Thorkild Karring • ISBN: 9781405160995 Textbook and Color Atlas of Traumatic Injuries to the Teeth, Fourth Edition Edited by Jens Andreasen, Frances Andreasen, Lars Andersson • ISBN: 9781405129541