The Quest for Cortisone

The Quest for Cortisone

Author: Thom Rooke

Publisher: MSU Press

Published: 2012-01-01

Total Pages: 376

ISBN-13: 1609173260

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In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound—cortisone—her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”


The Billion-Dollar Molecule

The Billion-Dollar Molecule

Author: Barry Werth

Publisher: Simon and Schuster

Published: 2013-08-20

Total Pages: 480

ISBN-13: 143912681X

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Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.


Dmso

Dmso

Author: Morton Walker D.P.M.

Publisher: Penguin

Published: 1993-01-01

Total Pages: 354

ISBN-13: 1101662344

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An easy-to-understand, up-to-date guide on the highly publicized drug, DMSO DMSO—dimethyl sulfoxide—is a simple by-product of wood and has been called a “miracle” drug, capable of relieving pain, diminishing swelling, reducing inflammation, encouraging healing, and restoring normal function. In this groundbreaking work, award-winning health science writer Dr. Morton Walker examines the powerful and compelling case for the use of DMSO in the treatment of many debilitating disease and health-related problems. In DMSO: Nature’s Healer, Dr. Walker cites documented cases of its astounding use in healing and prevention of a host of health disorders, including arthritis, stroke, cancer, mental retardation, and sports and auto injuries. He also recounts the dramatic story of the long struggle to gain FDA approval of DMSO.


The Way of the Samurai

The Way of the Samurai

Author: Inazo Nitobe

Publisher: Arcturus Publishing

Published: 2017-09-21

Total Pages: 89

ISBN-13: 1788880382

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This classic text by Inazo Nitobe defining the moral code of the warrior class or Samurai has had a huge impact both in the West and in Japan itself. Drawing on Japanese traditions such as Shinto and Buddhism, and citing parallels with Western philosophy and literature, Nitobe's text is essential reading for anyone who wishes to understand the culture and morals of Japan.


At Zero

At Zero

Author: Joe Vitale

Publisher: John Wiley & Sons

Published: 2013-10-31

Total Pages: 245

ISBN-13: 1118837479

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New stories and new processes that outline the fourth stage of awakening of ho'oponopono Author Joe Vitale's previous book, Zero Limits, presented a unique self-help breakthrough focused on helping overworked, overstressed individuals overcome obstacles and achieve their goals. It was the first book to explain how a secret Hawaiian method called ho'oponopono can help people experience health, wealth, happiness, and more. It empowered thousands of readers to take control of everything in their lives in order to achieve all they’ve ever dreamed of. At Zero starts where Zero Limits left off. It offers new stories, explains new process, and reveals the fourth stage of awakening. Explains the process called "cleaning," to delete programs and beliefs that you aren't aware of Shows how repeating the phrases I love you, I'm sorry, Please forgive me, Thank you can help you reach Divinity Life will always present you with challenges. The practice of ho'oponopono, as revealed by author Joe Vitale, guides you through the journey of life with the tools you need to rid yourself of hindrances and open yourself up to infinite possibilities.


The Antidote

The Antidote

Author: Barry Werth

Publisher: Simon and Schuster

Published: 2014-02-04

Total Pages: 448

ISBN-13: 1451655665

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In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.


The Rise and Fall of Modern Medicine

The Rise and Fall of Modern Medicine

Author: James Le Fanu

Publisher: Carroll & Graf Pub

Published: 2000

Total Pages: 426

ISBN-13: 9780786707324

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Argues that the pace of medical discoveries has slowed in the last twenty-five years due to excessive emphasis on the social and political aspects of health care, and to controversies caused by ethical issues.


General and Comparative Endocrinology

General and Comparative Endocrinology

Author: A.M. Schreiber

Publisher: CRC Press

Published: 2023-11-24

Total Pages: 678

ISBN-13: 1000913082

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General and Comparative Endocrinology: An Integrative Approach, takes a holistic approach to endocrinology, introducing students to the diverse facets of this interdisciplinary science ranging from the medical to comparative domains, while also exploring evolutionary, environmental, and conservation specializations within the field. The textbook is founded on the principle that students interested in the health sciences will benefit from understanding how proficiency in endocrine function among a diversity of organisms contributes to advances in modern medicine. Likewise, students intrigued by comparative physiology will benefit from the wealth of knowledge derived from medical/clinical endocrinology, the historical bedrock of the field. This textbook represents the modern field of endocrinology in its totality by addressing topics and recent advances not currently discussed in other introductory endocrinology textbooks. Key Features Introduces the broad and interdisciplinary scope of endocrinology. Provides clear chapter objectives and key concepts. Includes summary and synthesis questions for each chapter that are suitable for exams and quizzes. Includes a chapter devoted to endocrine-disrupting chemicals. Describes the roles played by the endocrine system in important health challenges related to appetite regulation, obesity, diabetes, and other diseases stemming from ‘mismatches to modernity’. Integrates evolutionary and comparative approaches to hormones and health.


Corticosteroids, An Issue of Rheumatic Disease Clinics of North America

Corticosteroids, An Issue of Rheumatic Disease Clinics of North America

Author: Marcy B. Bolster

Publisher: Elsevier Health Sciences

Published: 2016-01-19

Total Pages: 225

ISBN-13: 0323417132

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Corticosteroids represent the most important and frequently used class of anti-inflammatory and immunosuppressant agents in the management of many rheumatological conditions. Included in this issue will be articles on the following topics: Glucocorticoid use in intra-articular and soft tissue injections, corticosteroids and osteoporosis, corticosteroids in lupus, ANCA associated vasculitis, and many more!


Truevine

Truevine

Author: Beth Macy

Publisher: Little, Brown

Published: 2016-10-18

Total Pages: 496

ISBN-13: 0316337560

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The true story of two African-American brothers who were kidnapped and displayed as circus freaks, and whose mother endured a 28-year struggle to get them back. The year was 1899 and the place a sweltering tobacco farm in the Jim Crow South town of Truevine, Virginia. George and Willie Muse were two little boys born to a sharecropper family. One day a white man offered them a piece of candy, setting off events that would take them around the world and change their lives forever. Captured into the circus, the Muse brothers performed for royalty at Buckingham Palace and headlined over a dozen sold-out shows at New York's Madison Square Garden. They were global superstars in a pre-broadcast era. But the very root of their success was in the color of their skin and in the outrageous caricatures they were forced to assume: supposed cannibals, sheep-headed freaks, even "Ambassadors from Mars." Back home, their mother never accepted that they were "gone" and spent 28 years trying to get them back. Through hundreds of interviews and decades of research, Beth Macy expertly explores a central and difficult question: Where were the brothers better off? On the world stage as stars or in poverty at home? Truevine is a compelling narrative rich in historical detail and rife with implications to race relations today.