In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound—cortisone—her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”
The Myth. The Magic. Dominarian legends speak of a mighty conflict, obscured by the mists of history. Of a conflict between the brothers Urza and Mishra for supremacy on the continent of Terisiare. Of titantic engines that scarred and twisted the very planet. Of a final battle that sank continents and shook the skies. The saga of the Brothers’ War.
The story of the quest for a real-life Shangri-La in the darkest heart of the Himalayas– a century-long obsession to reach the sacred hidden center of one of the world's last uncharted realms. At the far eastern end of the Himalayas in Tibet lies the Tsangpo River Gorge, known as “the great romance of geography” during the nineteenth century's golden age of exploration. Here the mighty Tsangpo funnels into an impenetrable canyon three miles deep, walled off from the outside world by twenty-five thousand foot peaks. Like the earthly paradise of Shangri-La immortalized in James Hilton's classic 1933 novel Lost Horizon, the Tsangpo River Gorge is a refuge revered for centuries by Tibetan Buddhists–and later in Western imagination–as a sanctuary in times of strife as well as a gateway to nirvana. The Siege of Shangri-La tells the story of this fabled land's exploration as both a geographical and spiritual destination–and chronicles the discovery at the end of the last millennium of the truth behind the myths and rumors about it. Veteran journalist Michael McRae traces the gorge's exploratory history from the clandestine missions of surveyor-spies called pundits and botanical expeditions of naturalists in the early twentieth century to the recent investigations of scholars, adventurers, and pilgrims seeking the "Hidden Falls," of the Tsangpo, which purportedly rivals Niagara in size and serves as the gateway to paradise. Each explorer's narrative provides increasing evidence of why the gorge has been mythologized in Eastern and Western lore as one of the world's most alluring blanks on the map–and a supreme test of human will. Taking readers on a guided tour of the gorge's landscape, physical and metaphysical, McRae presents an insightful look at the pursuit of glory and enlightenment that has played out in this mysterious land with sometimes disastrous consequences. The Siege of Shangri-La is a fascinating journey through the inner recesses of a remote, mystical world and the minds of those who have attempted to reach it. From the Hardcover edition.
"Everything in here is true and if it ain't, it ought to be. I was born Nathanial James Buchannan and been called Buck from that day on. I lived most of my life on the frontier, from a cabin in the wilderness, to the Cherokee village of my father's family, to the cities in the east, to the mountains in the west, and back again. I've done some things in my time; fought many battles, some to kill those who needed killing, some to win freedom, been brother to a few, loved two women, lost a lot and gained more. All the while, I followed my spirit guide, my brother, the wolf. This is my story, my history, the best I recall. I've lived a good long while, some 88 years. The dates may be off some, 'cause I don't remember so well now. This writing will probably kill me. It is the hardest work I've ever done. Mine's a good story, and though I don't like the writing, I do like the telling, and I hope y'all enjoy the reading. I've sure enjoyed the living."
This book will prove controversial for several reasons, the main one being that it shows the vanquishing of the ancient cultural beliefs, of the ancient cultures, primarily around the Mediterranean that come today to be called ‘paganism’. This was not a one-off event. The victory of monotheism was the latest phase in an ongoing battle between Monotheism and what we can call the ‘Heliopean Pantheons’. Other contentious topics are innovative ideas affecting ancient Egyptian history and Biblical Dream Misinterpretation. Other topics are also discussed such as the proposed ‘Wave Nature of Cultures’ and ‘Cultural Compression’.
The Anglia Book Series (ANGB) offers a selection of high quality work on all areas and aspects of English philology. It publishes book-length studies and essay collections on English language and linguistics, on English and American literature and culture from the Middle Ages to the present, on the new English literatures, as well as on general and comparative literary studies, including aspects of cultural and literary theory.
FIVE HUNDRED YEARS AFTER HE SET SAIL, the dominant understanding of Christopher Columbus holds him responsible for almost everything that went wrong in the New World. Here, finally, is a book that will radically change our interpretation of the man and his mission. Scholar Carol Delaney claims that the true motivation for Columbus’s voyages is very different from what is commonly accepted. She argues that he was inspired to find a western route to the Orient not only to obtain vast sums of gold for the Spanish Crown but primarily to help fund a new crusade to take Jerusalem from the Muslims—a goal that sustained him until the day he died. Rather than an avaricious glory hunter, Delaney reveals Columbus as a man of deep passion, patience, and religious conviction. Delaney sets the stage by describing the tumultuous events that had beset Europe in the years leading up to Columbus’s birth—the failure of multiple crusades to keep Jerusalem in Christian hands; the devastation of the Black Plague; and the schisms in the Church. Then, just two years after his birth, the sacking of Constantinople by the Ottomans barred Christians from the trade route to the East and the pilgrimage route to Jerusalem. Columbus’s belief that he was destined to play a decisive role in the retaking of Jerusalem was the force that drove him to petition the Spanish monarchy to fund his journey, even in the face of ridicule about his idea of sailing west to reach the East. Columbus and the Quest for Jerusalem is based on extensive archival research, trips to Spain and Italy to visit important sites in Columbus’s life story, and a close reading of writings from his day. It recounts the drama of the four voyages, bringing the trials of ocean navigation vividly to life and showing Columbus for the master navigator that he was. Delaney offers not an apologist’s take, but a clear-eyed, thought-provoking, and timely reappraisal of the man and his legacy. She depicts him as a thoughtful interpreter of the native cultures that he and his men encountered, and unfolds the tragic story of how his initial attempts to establish good relations with the natives turned badly sour, culminating in his being brought back to Spain as a prisoner in chains. Putting Columbus back into the context of his times, rather than viewing him through the prism of present-day perspectives on colonial conquests, Delaney shows him to have been neither a greedy imperialist nor a quixotic adventurer, as he has lately been depicted, but a man driven by an abiding religious passion.
