Molecular Biology of the Cell
Author:
Publisher:
Published: 2002
Total Pages: 0
ISBN-13: 9780815332183
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The Pharmacology of Lymphocytes
Author: Michael A. Bray
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 633
ISBN-13: 3642732178
DOWNLOAD EBOOK"Immunopharmacology" , why not "pharmacoimmunology"? Professor H. O. Schild University College London, 1962 An intact immune response is essential for survival, as is evidenced by the various innate immune deficiency syndromes and by the emergence of the acquired immune deficiency syndrome (AIDS) as a pandemic during the last decade. Substances which stimulate the immune response might contribute to the therapy of AIDS and its precursor, AIDS-related syndrome, as well as of other clinical conditions in which immune responses can be diminished, such as carcinoma and infections. In other circumstances, an intact or heightened immune response may pose clinical problems; hence there is need to suppress, or diminish, components of the immune response. For instance, it is necessary to impair cellular immunity in order to ensure lasting acceptance of heterografts and it is already established that agents effective in transplantation are therapeutically effective in an range of autoimmune diseases. More recently, experimental studies have indicated that aberrant manifestations of humoral immunity, as in allergies, may also be amenable to pharmacological intervention.
Neuroimmune Pharmacology
Author: Tsuneya Ikezu
Publisher: Springer
Published: 2016-12-22
Total Pages: 1045
ISBN-13: 3319440225
DOWNLOAD EBOOKThe second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.
Holland-Frei Cancer Medicine
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
Published: 2017-03-10
Total Pages: 2004
ISBN-13: 111900084X
DOWNLOAD EBOOKHolland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
B Cell Receptor Signaling
Author: Tomohiro Kurosaki
Publisher: Springer
Published: 2015-12-26
Total Pages: 233
ISBN-13: 3319261339
DOWNLOAD EBOOKThis volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Pharmacology of Immunotherapeutic Drugs
Author: Clinton B. Mathias
Publisher: Springer Nature
Published: 2019-10-18
Total Pages: 410
ISBN-13: 3030199223
DOWNLOAD EBOOKMedicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are detailed. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
Williams Hematology, 9E
Author: Kenneth Kaushansky
Publisher: McGraw Hill Professional
Published: 2015-12-23
Total Pages: 2528
ISBN-13: 0071833013
DOWNLOAD EBOOKPublisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The world's most highly regarded reference text on the mechanisms and clinical management of blood diseases A Doody's Core Title for 2020! Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. It is acknowledged worldwide as the leading hematology resource, with editors who are internationally regarded for their research and clinical achievements and authors who are luminaries in their fields. The Ninth Edition of Williams Hematology is extensively revised to reflect the latest advancements in basic science, translational pathophysiology, and clinical practice. In addition to completely new chapters, it features a full-color presentation that includes 700 photographs, 300 of which are new to this edition, and 475 illustrations. Recognizing that blood and marrow cell morphology is at the heart of diagnostic hematology, informative color images of the relevant disease topics are conveniently integrated into each chapter, allowing easy access to illustrations of cell morphology important to diagnosis. Comprehensive in its depth and breath, this go-to textbook begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.
Therapeutic Antibodies
Author: Yuti Chernajovsky
Publisher: Springer
Published: 2007-11-22
Total Pages: 380
ISBN-13: 9783540732587
DOWNLOAD EBOOKThis essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.
Lehne's Pharmacology for Nursing Care - E-Book
Author: Jacqueline Rosenjack Burchum
Publisher: Elsevier Health Sciences
Published: 2014-12-02
Total Pages: 1427
ISBN-13: 0323340261
DOWNLOAD EBOOKKnown for its clear explanations of drug prototypes and how they work, Lehne's Pharmacology for Nursing Care, 9th Edition provides a solid understanding of key drugs and their implications for nursing care. A perennial student favorite, this book simplifies complex concepts, using large and small print to distinguish need-to-know drug content from the material that’s merely nice to know. New to this edition are quick-reference summaries of prototype drugs, safety alerts, and a stronger QSEN focus. Written by noted nursing pharmacology instructors Jacqueline Burchum and Laura Rosenthal, this text helps you understand pharmacology as opposed to merely memorizing drug facts. UNIQUE! Engaging writing style with clear explanations makes difficult pharmacology concepts easy to grasp and even enjoyable to learn. Large print highlights essential, need-to-know information, and small print indicates nice-to-know information. A drug prototype approach focuses on one representative drug within each drug family that characterizes all members of its group, so that you can apply your understanding to related drugs currently on the market as well as drugs that will be released in the future. Nursing implications of drug therapy are integrated throughout the text and summarized at the end of chapters, demonstrating the vital relationship between drug therapy and nursing care. Reader-friendly features make learning easier with concise drug summary tables, chapter outlines, key points, and a visual guide to the prototype drugs in each class. Learning resources on an Evolve companion website include video clips, animations, case studies, and NCLEX® exam-style review questions. Coverage of dietary supplements and herbal remedies describes potential dangerous interactions between prescribed and over-the-counter drugs and dietary supplements. NEW! QSEN focus includes Patient-Centered Care Across the Life Span features highlighting safe and appropriate patient care during different phases of life. NEW Safety Alert features emphasize the QSEN competency relating to patient safety. NEW! Prototype Drugs features serve as a quick-reference aid to learning. NEW! Chapter outlines include page numbers to help you locate topics quickly. UPDATED Special Interest Topic boxes use engaging vignettes to focus on emerging and currently trending issues in pharmacology. NEW authors continue Dr. Lehne’s clear, unique writing style, with the same accuracy and state-of-the-science updates.
Advanced Hematology in Integrated Cardiovascular Chinese Medicine
Author: Anika Niambi Al-Shura
Publisher: Academic Press
Published: 2019-10-20
Total Pages: 124
ISBN-13: 0128175737
DOWNLOAD EBOOKAdvanced Hematology in Integrative Cardiovascular Chinese Medicine, volume three in the Integrative Cardiovascular Chinese Medicine series, systematically observes and discusses laboratory tests which detect heart diseases and analyzes the results. It includes coverage of red and white blood cell homeostasis and advanced anatomy and physiology of the vascular system, including the biomedicine perspectives of blood and lymphatic system, and TCM perspectives of essence, qi, blood and body fluid. In addition, the book examines the immune system from the perspective of Traditional Chinese Medicine, including pestilential differentiation. Case studies, lab charts and laboratory differentials according to Chinese and Western medicine perspectives are also included. Finally, the book discusses the use of lab results for assisting and/or confirming diagnoses of blood and cardiovascular disorders in both Traditional Chinese Medicine and Western medicine. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration. Compares medical theories in Chinese medicine and Western medicine on blood, immune system and cardiovascular diseases Provides laboratory cases, tests and values concerning pathology of the blood and the cardiovascular system necessary for diagnosing and monitoring within integrative cardiovascular Chinese medicine Includes coverage of advanced level blood, complement and immune systems from both Western and Chinese medicine perspectives
