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Author: William B. Provine
Publisher: University of Chicago Press
Published: 2020-07-24
Total Pages: 224
ISBN-13: 022678892X
DOWNLOAD EBOOKTracing the development of population genetics through the writings of such luminaries as Darwin, Galton, Pearson, Fisher, Haldane, and Wright, William B. Provine sheds light on this complex field as well as its bearing on other branches of biology.
Author: Thomas Nagylaki
Publisher: Springer Science & Business Media
Published: 2013-03-12
Total Pages: 381
ISBN-13: 364276214X
DOWNLOAD EBOOKThis book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).
Author: Alan R. Templeton
Publisher: John Wiley & Sons
Published: 2006-09-29
Total Pages: 720
ISBN-13: 0470047216
DOWNLOAD EBOOKThe advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics. Population Genetics and Microevolutionary Theory takes a modern approach to population genetics, incorporating modern molecular biology, species-level evolutionary biology, and a thorough acknowledgment of quantitative genetics as the theoretical basis for population genetics. Logically organized into three main sections on population structure and history, genotype-phenotype interactions, and selection/adaptation Extensive use of real examples to illustrate concepts Written in a clear and accessible manner and devoid of complex mathematical equations Includes the author's introduction to background material as well as a conclusion for a handy overview of the field and its modern applications Each chapter ends with a set of review questions and answers Offers helpful general references and Internet links
Author: Theodosius Dobzhansky
Publisher:
Published: 2013
Total Pages: 364
ISBN-13:
DOWNLOAD EBOOKAuthor: Motoo Kimura
Publisher: Princeton University Press
Published: 2020-03-31
Total Pages: 233
ISBN-13: 0691210098
DOWNLOAD EBOOKTo show the importance of stochastic processes in the change of gene frequencies, the authors discuss topics ranging from molecular evolution to two-locus problems in terms of diffusion models. Throughout their discussion, they come to grips with one of the most challenging problems in population genetics--the ways in which genetic variability is maintained in Mendelian populations. R.A. Fisher, J.B.S. Haldane, and Sewall Wright, in pioneering works, confirmed the usefulness of mathematical theory in population genetics. The synthesis their work achieved is recognized today as mathematical genetics, that branch of genetics whose aim is to investigate the laws governing the genetic structure of natural populations and, consequently, to clarify the mechanisms of evolution. For the benefit of population geneticists without advanced mathematical training, Professors Kimura and Ohta use verbal description rather than mathematical symbolism wherever practicable. A mathematical appendix is included.
Author: Sewall Wright
Publisher: University of Chicago Press
Published: 1986-09
Total Pages: 664
ISBN-13: 9780226910536
DOWNLOAD EBOOKThis volume emphasizes the period before 1950. During this period Wright thought of himself primarily as an experimental physiological geneticist rather than as a theoretical population geneticist.
Author: Motoo Kimura
Publisher: University of Chicago Press
Published: 1994
Total Pages: 736
ISBN-13: 9780226435633
DOWNLOAD EBOOKOne of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution—the neutral theory—and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change. Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and random drift account for variations at the level of DNA and amino acids, Kimura advanced a theory of evolutionary change that was strongly challenged at first and that eventually earned the respect and interest of evolutionary biologists throughout the world. This volume includes the seminal papers on the neutral theory, as well as many others that cover such topics as population structure, variable selection intensity, the genetics of quantitative characters, inbreeding systems, and reversibility of changes by random drift. Background essays by Naoyuki Takahata examine Kimura's work in relation to its effects and recent developments in each area.
Author: Gerd B. Muller
Publisher: MIT Press
Published: 2003-01-03
Total Pages: 354
ISBN-13: 9780262134194
DOWNLOAD EBOOKA more comprehensive version of evolutionary theory that focuses as much on the origin of biological form as on its diversification. The field of evolutionary biology arose from the desire to understand the origin and diversity of biological forms. In recent years, however, evolutionary genetics, with its focus on the modification and inheritance of presumed genetic programs, has all but overwhelmed other aspects of evolutionary biology. This has led to the neglect of the study of the generative origins of biological form. Drawing on work from developmental biology, paleontology, developmental and population genetics, cancer research, physics, and theoretical biology, this book explores the multiple factors responsible for the origination of biological form. It examines the essential problems of morphological evolution—why, for example, the basic body plans of nearly all metazoans arose within a relatively short time span, why similar morphological design motifs appear in phylogenetically independent lineages, and how new structural elements are added to the body plan of a given phylogenetic lineage. It also examines discordances between genetic and phenotypic change, the physical determinants of morphogenesis, and the role of epigenetic processes in evolution. The book discusses these and other topics within the framework of evolutionary developmental biology, a new research agenda that concerns the interaction of development and evolution in the generation of biological form. By placing epigenetic processes, rather than gene sequence and gene expression changes, at the center of morphological origination, this book points the way to a more comprehensive theory of evolution.
Author: William B. Provine
Publisher:
Published: 1971
Total Pages: 201
ISBN-13: 9780226684659
DOWNLOAD EBOOKTracing the development of population genetics through the writings of such luminaries as Darwin, Galton, Pearson, Fisher, Haldane, and Wright, William B. Provine sheds light on this complex field as well as its bearing on other branches of biology.
Author: S. Sarkar
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 322
ISBN-13: 9401128561
DOWNLOAD EBOOKgenetics. " It is simply the appropriation of that term, very likely with insufficient knowledge and respect for its past usage. For that, the Editor alone is responsible and requests tolerance. He has, as far as he can tell, no intention or desire to use it for any historiographical purposes other than that just mentioned. Even more important, the decision to consider Muller together with Fisher, Haldane and Wright is also not original. Crow (1984) has already done so, arguing persua sively that Muller was "keenly interested in evolution and made sub stantial contributions to the development of the neo-Darwinian view. " Crow's reasons for considering these four figures together and the reasons discussed above are complementary. This book continues a historiographical choice he initiated; others will have to judge whether it is appropriate. The foregoing considerations were intended to show why Fisher, Haldane, Muller and Wright should be considered together in the history of theoretical evolutionary genetics. I By a welcome stroke of luck, from the point of view of the Editor, all four of these figures were born almost together, between 1889 and 1892, and almost exactly a century ago. It therefore seemed appropriate to use their birth cente naries to consider their work together. A conference was held at Boston University, on March 6, 1990, under the auspices of the Boston Center for the Philosophy and History of Science, to discuss their work. This book has emerged mainly from that conference.
