The Eye's Aqueous Humor: From Secretion to Glaucoma

The Eye's Aqueous Humor: From Secretion to Glaucoma

Author:

Publisher: Academic Press

Published: 1997-02-09

Total Pages: 311

ISBN-13: 0080585167

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This volume presents a basic consensus of how the aqueous humor is formed and exits through the trabecular meshwork and canal of Schlemm. It presents a timely update to current knowledge of the molecular transport mechanisms which underlie aqueous humor dynamics. In addition, it provides a concise description of the clinical approaches used for assessing these basic transport processes. The book emphasizes the phenomenon of the diurnal rhythm of aqueous humor formation, from both the clinical and molecular points of view. This phenomenon provides the major indication that aqueous humor secretion is regulated. - Introduces the mechanisms of aqueous humor formation and outflow - Describes the clinical study of aqueous humor dynamics - Exposes the research approaches currently applied - Emphasizes the diurnal rhythm of aqueous humor secretion - Provides awareness of unanswered questions


Advances in Ocular Toxicology

Advances in Ocular Toxicology

Author: Keith Green

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 282

ISBN-13: 1461559375

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This volume represents the proceedings of the Fifth Congress of the International Society of Ocular Toxicology (ISOT), which was held at the Grove Park Inn and Resort in Asheville, North Carolina, October 13-17, 1996. We are delighted to present this volume to the ophthalmic community, especially those with a significant interest in ocular toxicol ogy. The Fifth Congress was developed around themes relating to ocular drug metabolism, the ocular pathophysiological effects of nitric oxide, government issues relating to the use of alternative methods for toxicity testing, and a workshop that encompassed comparisons of both in vitro versus in vivo models as well as different animal models. The outcome of this congress, embodied in this volume, is a contribution to the methodologies currently employed or under development and to various drug or physical effects on different ocular tissues. While the focus of this proceedings is on ocular effects of drugs or other materials, many of the contributions deal with topics that have a much broader interest. The workshop concerning the use of different model systems and the choice of the best animal model for drug testing covers a wide range of interests that ex tends far beyond specific ocular effects. This is especially true in the area of alternative methods and in the choice of the best animal model for examination of different disease entities.


Barriers and Fluids of the Eye and Brain

Barriers and Fluids of the Eye and Brain

Author: Malcolm Beverley Segal

Publisher: CRC Press

Published: 1992

Total Pages: 262

ISBN-13: 9780849377075

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This volume presents the latest findings regarding the control of the fluid environments of the eye and brain. The book is comprised of papers presented at a symposium honoring the 80th birthday of Professor Hugh Davson. The contributors are previous students of Hugh Davson who are now leading authorities in the fields of the eye and brain. The eye is considered from its many interfaces, including the role of prostaglandins, blood flow in diabetes, and the vitreous body. Other topics discussed include the role of carbonic anhydrase, cerebrospinal fluid and its drainage, and the development of the blood/brain barrier to macromolecules. The book also shows how recent findings about homologous molecules refute earlier studies with foreign tracers, and offers a fascinating glimpse into the future with a description of the latest imaging techniques used in neurological diagnosis.


Biopharmaceutics of Ocular Drug Delivery

Biopharmaceutics of Ocular Drug Delivery

Author: Peter Edman

Publisher: CRC Press

Published: 2019-08-15

Total Pages: 215

ISBN-13: 1000693775

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A significant new book on drug delivery to the eye Biopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.


TOXICOLOGY OF THE EYE

TOXICOLOGY OF THE EYE

Author: W. Morton Grant

Publisher: Charles C Thomas Publisher

Published: 1993-01-01

Total Pages: 1619

ISBN-13: 0398082154

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The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.


The Eye's Aqueous Humor

The Eye's Aqueous Humor

Author:

Publisher: Academic Press

Published: 2008-11-03

Total Pages: 520

ISBN-13: 0080920519

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Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. - Guest edited by cell membrane experts - Dynamic and thorough coverage of all aspects of the aqueous humor from inflow to outflow - Provides the latest teachings on genomics and glaucoma - Highlights new therapeutic strategies for the control of intraocular pressure


Shields Textbook of Glaucoma

Shields Textbook of Glaucoma

Author: R. Rand Allingham

Publisher: Lippincott Williams & Wilkins

Published: 2012-03-28

Total Pages: 1278

ISBN-13: 1451147821

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Thoroughly updated, and now in full color, Shields' Textbook of Glaucoma, Sixth Edition is a clinically focused and practical textbook for general ophthalmologists treating patients with glaucoma. This classic text offers a rational approach to the medical and surgical management of glaucoma and presents a total care plan for the patient. This edition has five new or reconfigured chapters—management of the glaucoma patient/approach to the patient; principles of medical therapy; adrenergic agonists and antagonists; cholinergic stimulators and hyperosmotic agents; and neuroprotection and other investigational drugs. The book examines new technologies for intraocular pressure assessment and current diagnostic technologies such as optical coherence tomography, spectral domain optical coherence tomography, Heidelberg retinal tomograph, and GDx. Noted experts detail advances in surgical treatment of glaucoma including new glaucoma implants and angle surgery. Coverage also includes advances in genetics of glaucomatous diseases. A companion website includes the fully searchable text and an image bank.


Principles and Practice of Ophthalmology E-Book

Principles and Practice of Ophthalmology E-Book

Author: Daniel M. Albert

Publisher: Elsevier Health Sciences

Published: 2008-02-27

Total Pages: 5689

ISBN-13: 1437721117

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Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustrated coverage of every scientific and clinical principle in ophthalmology ensures that you will always be able to find the guidance you need to diagnose and manage your patients' ocular problems and meet today's standards of care. Updates include completely new sections on "Refractive Surgery" and "Ethics and Professionalism"... an updated and expanded "Geneitcs" section... an updated "Retina" section featuring OCT imaging and new drug therapies for macular degeneration... and many other important new developments that affect your patient care. A streamlined format and a new, more user-friendly full-color design - with many at-a-glance summary tables, algorithms, boxes, diagrams, and thousands of phenomenal color illustrations - allows you to locate the assistance you need more rapidly than ever.