Melanocortins—Advances in Research and Application: 2013 Edition

Melanocortins—Advances in Research and Application: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-06-21

Total Pages: 62

ISBN-13: 1481677497

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Melanocortins—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Melanocyte-Stimulating Hormones in a concise format. The editors have built Melanocortins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Melanocyte-Stimulating Hormones in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Melanocortins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Hyperbolically Embedded Subgroups and Rotating Families in Groups Acting on Hyperbolic Spaces

Hyperbolically Embedded Subgroups and Rotating Families in Groups Acting on Hyperbolic Spaces

Author: F. Dahmani

Publisher: American Mathematical Soc.

Published: 2017-01-18

Total Pages: 164

ISBN-13: 1470421941

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he authors introduce and study the notions of hyperbolically embedded and very rotating families of subgroups. The former notion can be thought of as a generalization of the peripheral structure of a relatively hyperbolic group, while the latter one provides a natural framework for developing a geometric version of small cancellation theory. Examples of such families naturally occur in groups acting on hyperbolic spaces including hyperbolic and relatively hyperbolic groups, mapping class groups, , and the Cremona group. Other examples can be found among groups acting geometrically on spaces, fundamental groups of graphs of groups, etc. The authors obtain a number of general results about rotating families and hyperbolically embedded subgroups; although their technique applies to a wide class of groups, it is capable of producing new results even for well-studied particular classes. For instance, the authors solve two open problems about mapping class groups, and obtain some results which are new even for relatively hyperbolic groups.


Spin Physics

Spin Physics

Author: Donald G. Crabb

Publisher: American Inst. of Physics

Published: 2009-08-25

Total Pages: 1236

ISBN-13: 9780735406865

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The topics covered in the conference ranged from the physics that can be done with polarized beams of particles (protons, electrons, gamma-rays, etc.) to the techniques and instrumentation necessary to achieve this. Topics included: nucleon structure measurements (from where does the spin of the proton and neutron come), the acceleration, storage and polarization of particle beams and the polarized targets and sources necessary for mounting the experiments.


RT-PCR Protocols

RT-PCR Protocols

Author: Nicola King

Publisher: Springer Science & Business Media

Published: 2008-02-04

Total Pages: 370

ISBN-13: 159259283X

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Until the mid 1980s, the detection and quantification of a specific mRNA was a difficult task, usually only undertaken by a skilled molecular biologist. With the advent of PCR, it became possible to amplify specific mRNA, after first converting the mRNA to cDNA via reverse transcriptase. The arrival of this technique—termed reverse transcription-PCR (RT-PCR)—meant that mRNA suddenly became amenable to rapid and sensitive analysis, without the need for advanced training in molecular biology. This new accessibility of mRNA, which has been facilitated by the rapid accumulation of sequence data for human mRNAs, means that every biomedical researcher can now include measurement of specific mRNA expression as a routine component of his/her research plans. In view of the ubiquity of the use of standard RT-PCR, the main objective of RT-PCR Protocols is essentially to provide novel, useful applications of RT-PCR. These include some useful adaptations and applications that could be relevant to the wider research community who are already familiar with the basic RT-PCR protocol. For example, a variety of different adaptations are described that have been employed to obtain quantitative data from RT-PCR. Quantitative RT-PCR provides the ability to accurately measure changes/imb- ances in specific mRNA expression between normal and diseased tissues.


Neural Control of Renal Function

Neural Control of Renal Function

Author: Ulla Kopp

Publisher: Morgan & Claypool Publishers

Published: 2011

Total Pages: 99

ISBN-13: 1615042318

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The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References


Sodium in Health and Disease

Sodium in Health and Disease

Author: Michael Burnier

Publisher: CRC Press

Published: 2007-11-16

Total Pages: 478

ISBN-13: 1420020943

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report on the latest developments in the field with new information in basic as well as in clinical sciences, Sodium in Health Diseases, covers both the physiology of sodium balance and how it relates to disease. Expertly written, its concise text examines ATPase, transport and receptor systems, and sodium balance as it relates to sex hormon


Hypertension Primer

Hypertension Primer

Author: Joseph L. Izzo

Publisher:

Published: 2015-04-24

Total Pages: 640

ISBN-13: 9781469876665

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Now in its thoroughly updated Fourth Edition, the Hypertension Primer is a comprehensive, readable source of state-of-the-art scientific and clinical information on hypertension. The book contains 171 short chapters by distinguished experts that cover every aspect of hypertension and its pathogenesis, epidemiology, impact, and management. Highlights of this edition include updated JNC 7 findings regarding special population therapy and clinical management. Chapters are grouped into three well-organized sections--basic science, population science, and clinical management--and each chapter is cross-referenced to other relevant chapters. Each chapter is easily digestible and begins with a bulleted list of key points.


Functional Imaging in Oncology

Functional Imaging in Oncology

Author: Antonio Luna

Publisher: Springer Science & Business Media

Published: 2013-12-11

Total Pages: 557

ISBN-13: 364240412X

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In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This well-illustrated two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including preclinical and clinical imaging techniques, based on US, CT, MRI, PET and hybrid modalities. This first volume explains the biophysical basis for these functional imaging techniques and describes the techniques themselves. Detailed information is provided on the imaging of cancer hallmarks, including angiogenesis, tumor metabolism, and hypoxia. The techniques and their roles are then discussed individually, covering the full range of modalities in clinical use as well as new molecular and functional techniques. The value of a multiparametric approach is also carefully considered.