The Melanocortin System
The Melanocortin System

Author: Roger D. Cone

Publisher:

Published: 2003

Total Pages: 416

ISBN-13:

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In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.

The Melanocortin System
The Melanocortin System

Author: Roger D. Cone

Publisher:

Published: 2003

Total Pages: 416

ISBN-13:

DOWNLOAD EBOOK

In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.

The Melanocortin System
The Melanocortin System

Author: Roger D. Cone

Publisher:

Published: 2003

Total Pages: 416

ISBN-13:

DOWNLOAD EBOOK

In the decade before the publication of this study, melanocortin biology matured. Three additional receptors were discovered, and animal models were established addressing the function of each receptor. Researchers now know that the diverse physiologic responses to melanocortins - including their role in development, weight and endocrine regulation, cortisol production, secretion from exocrine glands, and pigmentation - can be defined in terms of individual receptors. In this text, contributors from the field of evolutionary biology, peptide chemistry, pigmentation biology, neuroscience, endocrinology and genetics provide the reader with a comprehensive review of melanocortin biology. Six areas of active research are addressed: peptide and small molecule chemistry; receptor structure and function; energy homeostasis; pigmentation; adrenocorticol function; and behaviour. There are 56 papers and 20 posters altogether, taken from the Fifth Melanocortin Meeting, held in 2002.

The Pigmentary System
The Pigmentary System

Author: James J. Nordlund

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 1333

ISBN-13: 140515733X

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The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.

The Melanocortin Receptors
The Melanocortin Receptors

Author: Roger D. Cone

Publisher: Springer Science & Business Media

Published: 2000-03-14

Total Pages: 576

ISBN-13:

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Roger Cone and a distinguished team of expert investigators provide the first major treatment of this critically important receptor family. The book illuminates the structure and function of these receptors through a wide-ranging review of the latest findings concerning the biology, physiology, and pharmacology of their peptide ligands and covers the major melanocortin peptides, Melanocortin-1-Receptors through Melanocortin-5-Receptors. Topics include the characterization of the melanocortin receptors, the biochemical mechanism of receptor action, and receptor function and regulation. Timely and authoritative, The Melanocortin Receptors offers an up-to-date knowledge base on the remarkably complex structure and functions of the melanocortins, a guide that will prove invaluable for today's neuroscientists, endocrinologists, pharmacologists, and other clinical and experimental investigators working in this fast moving field.

G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis
G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis

Author:

Publisher: Academic Press

Published: 2013-01-10

Total Pages: 403

ISBN-13: 0123869528

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Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans. - Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs - Chapters are written by leading experts

Handbook of Neuroendocrinology
Handbook of Neuroendocrinology

Author: George Fink

Publisher: Academic Press

Published: 2012

Total Pages: 895

ISBN-13: 0123750970

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Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Obesity and Binge Eating Disorder
Obesity and Binge Eating Disorder

Author: Simone Munsch

Publisher: Karger Medical and Scientific Publishers

Published: 2005-01-01

Total Pages: 233

ISBN-13: 3805578326

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Overweight and obesity have quite recently become a major problem affecting many countries worldwide. This publication gives a comprehensive overview on the current knowledge of the pathophysiological mechanisms in the regulation of hunger and satiety. An

Vitiligo
Vitiligo

Author: Somesh Gupta

Publisher: John Wiley & Sons

Published: 2018-04-30

Total Pages: 533

ISBN-13: 1118937414

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Practical guidance based on expert experience and evidence for developing management strategies for vitiligo This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world’s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case. Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease’s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more. Thoroughly guides those involved in the clinical aspects of vitiligo Aids diagnosis and classification of severity Balances evidence and experience Compiled by world-leading expert editors Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.

The Genetics of Obesity
The Genetics of Obesity

Author: Claude Bouchard

Publisher: CRC Press

Published: 1994-03-28

Total Pages: 262

ISBN-13: 9780849348808

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This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.