Skin Barrier Function
Skin Barrier Function

Author: T. Agner

Publisher: Karger Medical and Scientific Publishers

Published: 2016-02-04

Total Pages: 172

ISBN-13: 3318055867

DOWNLOAD EBOOK

Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.

How to Practice Academic Medicine and Publish from Developing Countries?
How to Practice Academic Medicine and Publish from Developing Countries?

Author: Samiran Nundy

Publisher: Springer Nature

Published: 2021-10-23

Total Pages: 475

ISBN-13: 9811652481

DOWNLOAD EBOOK

This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.

Medical Biostatistics
Medical Biostatistics

Author: Abhaya Indrayan

Publisher: CRC Press

Published: 2017-11-27

Total Pages: 1245

ISBN-13: 135158555X

DOWNLOAD EBOOK

Encyclopedic in breadth, yet practical and concise, Medical Biostatistics, Fourth Edition focuses on the statistical aspects ofmedicine with a medical perspective, showing the utility of biostatistics as a tool to manage many medical uncertainties. This edition includes more topics in order to fill gaps in the previous edition. Various topics have been enlarged and modified as per the new understanding of the subject.

Principles of Translational Science in Medicine
Principles of Translational Science in Medicine

Author: Martin Wehling

Publisher: Academic Press

Published: 2015-04-02

Total Pages: 365

ISBN-13: 0128007214

DOWNLOAD EBOOK

Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. - Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development - New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies - Details IPR issues of translation, especially for public-private-partnerships - Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Presenting Medical Statistics from Proposal to Publication
Presenting Medical Statistics from Proposal to Publication

Author: Janet L. Peacock

Publisher: Oxford University Press

Published: 2017-07-21

Total Pages: 307

ISBN-13: 0192526731

DOWNLOAD EBOOK

As many medical and healthcare researchers have a love-hate relationship with statistics, the second edition of this practical reference book may make all the difference. Using practical examples, mainly from the authors' own research, the book explains how to make sense of statistics, turn statistical computer output into coherent information, and help decide which pieces of information to report and how to present them. The book takes you through all the stages of the research process, from the initial research proposal, through ethical approval and data analysis, to reporting on and publishing the findings. Helpful tips and information boxes, offer clear guidance throughout, including easily followed instructions on how to: -develop a quantitative research proposal for ethical/institutional approval or research funding -write up the statistical aspects of a paper for publication -choose and perform simple and more advanced statistical analyses -describe the statistical methods and present the results of an analysis. This new edition covers a wider range of statistical programs - SAS, STATA, R, and SPSS, and shows the commands needed to obtain the analyses and how to present it, whichever program you are using. Each specific example is annotated to indicate other scenarios that can be analysed using the same methods, allowing you to easily transpose the knowledge gained from the book to your own research. The principles of good presentation are also covered in detail, from translating relevant results into suitable extracts, through to randomised controlled trials, and how to present a meta-analysis. An added ingredient is the inclusion of code and datasets for all analyses shown in the book on our website (http://medical-statistics.info). Written by three experienced biostatisticians based in the UK and US, this is a step-by-step guide that will be invaluable to researchers and postgraduate students in medicine, those working in the professions allied to medicine, and statisticians in consultancy roles.

Mosquitoes of the World
Mosquitoes of the World

Author: Richard C. Wilkerson

Publisher: Johns Hopkins University Press

Published: 2021-01-19

Total Pages: 1332

ISBN-13: 1421438143

DOWNLOAD EBOOK

The definitive reference on the biology, evolution, ecology, and diversity of all known species of the world's mosquitoes. Critical for entomologists, public health professionals, and epidemiologists across the world. Biting multiple times on two, three, or more different hosts, it is no surprise that some species of mosquitoes have co-evolved with pathogens. For humans and other animals, the result has been some of the most challenging diseases known. It has been said that Anopheles gambiae, as the primary transmitter of malaria parasites to humans, is the most dangerous animal in the world. Certainly malaria has killed more people than all the wars that ever took place. Even now, despite drugs and mosquito control, malaria claims the lives of 405,000 per year. The vast majority of mosquito species are not involved in pathogen transmission to humans, but those that are make a huge impact on global health. In this two-volume set, three of the world's leading experts on mosquito disease, ecology, and systematics offer readers unique insights into the fascinating world of mosquitoes while illustrating their diagnostic morphological features in detail. Comprehensively addressing the natural diversity of mosquitoes, the book explains their life histories, bionomic traits, and the physiological and physical adaptations they evolved in response to ever-changing environmental conditions. Mosquitoes are one of the best-known groups of insects, making this book a great starting place for anyone who would like to understand entomology by knowing the details about a representative family. Volume One contains a review of the biology and diversity of mosquitoes. Biology is treated in the following chapters: • Evolution • Nomenclature • Distribution • Development • Dormancy • Mosquito Movement • Feeding and Nutrition • Excretion • Copulation and Insemination • Egg Development and Oviposition The chapters on biology are followed by a well-illustrated summary of the characteristics of all 41 genera and of representative species of mosquitoes. This treatment of the morphological diversity of mosquitoes is accompanied by a glossary of all morphological terms used. Volume Two features • a long-awaited comprehensive mosquito taxonomic catalog detailing the current taxonomic and systematic status of all 3,698 valid species and subspecies, 41 genera, and 187 subgenera • a list of all taxa for definitive use of nomenclature • complete lists of species synonyms, distributions, key taxonomic works, and newly defined informal names • origins of scientific names Readers will discover that some mosquitoes undertake courtship rituals, while others guard their eggs, feed solely on earthworms, or can survive as immatures under ice sheets or in salt-encrusted pools. Hundreds of drawings and high-resolution, close-up images illustrate the text. The most complete reference work on mosquitoes ever produced, Mosquitoes of the World is an unmatched resource for entomologists, public health professionals, epidemiologists, and reference libraries.