Reproductive and Developmental Toxicology

Reproductive and Developmental Toxicology

Author: Ramesh C Gupta

Publisher: Academic Press

Published: 2022-02-11

Total Pages: 1558

ISBN-13: 0323915604

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**Selected for Doody's Core TitlesĀ® 2024 in Toxicology** Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. - Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development - Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis - Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more


Acta Ornithologica

Acta Ornithologica

Author:

Publisher:

Published: 1993

Total Pages: 498

ISBN-13:

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Articles issued in English in the original journal are not included in the translation edition.


Animal Biomarkers as Pollution Indicators

Animal Biomarkers as Pollution Indicators

Author: David B. Peakall

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 312

ISBN-13: 9401123462

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Ecotoxicology is a relatively new scientific discipline. Indeed, it might be argued that it is only during the last 5-10 years that it has come to merit being regarded as a true science, rather than a collection of procedures for protecting the environment through management and monitoring of pollutant discharges into the environment. The term 'ecotoxicology' was first coined in the late sixties by Prof. Truhaut, a toxicologist who had the vision to recognize the importance of investigating the fate and effects of chemicals in ecosystems. At that time, ecotoxicology was considered a sub-discipline of medical toxicology. Subsequently, several attempts have been made to portray ecotoxicology in a more realistic light. Notably, both F. Moriarty (1988) and F. Ramade (1987) emphasized in their books the broad basis of ecotoxicology, encompassing chemical and radiation effects on all components of ecosystems. In doing so, they and others have shifted concern from direct chemical toxicity to man, to the far more subtle effects that pollutant chemicals exert on natural biota. Such effects potentially threaten the existence of all life on Earth. Although I have identified the sixties as the era when ecotoxicology was first conceived as a coherent subject area, it is important to acknowledge that studies that would now be regarded as ecotoxicological are much older. Wherever people's ingenuity has led them to change the face of nature significantly, it has not escaped them that a number of biological con sequences, often unfavourable, ensue.


Pathological Effects of Lead Intoxication in Japanese Quails

Pathological Effects of Lead Intoxication in Japanese Quails

Author: Sajid Umar Khan

Publisher: LAP Lambert Academic Publishing

Published: 2012-06

Total Pages: 68

ISBN-13: 9783659163739

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Lead (Pb) is an environmental pollutant, especially due to its anthropogenic activity.The present study aimed to investigate some of the toxic effects of lead exposure in quails and its amelioration through vitamin E supplementation. A total number of 420, day old chicks of Japanese quail were assigned seven dietary treatments.. Control group received only basal diet without any supplementation. Other groups received lead (Pb) alone or in different combinations with vitamin E. Lead (Pb) was administered in the feed at a dose level of 50, 75 and 100 mg/kg Pb. Vitamin E was administered in the feed at a dose level of 40mg/kg vit E .The body weight of each bird was weighed weekly and found significant changes in the weight of quails. Pathological lesions in lead (Pb) fed birds included enlarged, pale, friable liver and swollen kidneys.On the other hand, supplementation of vitamins E in lead intoxicated birds showed ameliorative effects in Lead (pb) toxicity. It was concluded that the vitamin E ameliorated the lead induced toxic effects in some of parameters studied