The Chemokine Factsbook
The Chemokine Factsbook

Author: Krishna Vaddi

Publisher: Elsevier

Published: 1997-04-01

Total Pages: 219

ISBN-13: 0080529089

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How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalog of the essential properties of families of molecules. Gene organization, amino acid sequences, physicochemical properties, and biological activity are presented using a common, easy-to-follow format. Taken together they compile everything you want to know about proteins but are too busy to look for. The Chemokine FactsBook contains more than 40 entries on chemokines, and chemokine receptors from human or other origin, including IL-8, MCP-1, C5-a, RANTES, Lymphotactin, and CC CKR-1. The text provides information on tissue sources, target cells, physicochemical properties, transcription factors, regulation of expression in disease, receptor-binding characteristics, gene structure and location, amino acid sequences, and accession numbers and references. - Contains over 40 entries on chemokines and chemokine receptors from human or other origin, including: - IL-8 - MCP-1 - C5-a - RANTES - Lymphotactin - CC CKR-1 - Entries provide information on: - Tissue sources - Target cells - Physicochemical properties - Transcription factors - Regulation of expression - Expression in disease - Receptor-binding characteristics - Gene structure and location - Amino acid sequences - Database accession numbers - References

The Cytokine Factsbook and Webfacts
The Cytokine Factsbook and Webfacts

Author: Katherine A. Fitzgerald

Publisher: Academic Press

Published: 2001-10-09

Total Pages: 534

ISBN-13: 9780121551421

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Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.

The Leucocyte Antigen Factsbook
The Leucocyte Antigen Factsbook

Author: A. Neil Barclay

Publisher: Elsevier

Published: 1997-06-22

Total Pages: 626

ISBN-13: 0080535437

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A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references. The introductory chapters have also been updated, especially in terms of nomenclature, the role of the World Wide Web, and new structural data. The Leucocyte Antigen FactsBook, Second Edition contains more than 200 entries, with approximately 70 new entries, on all the molecules specifically expressed in the surface of cells of the haematopoietic system, including all characterized CD antigens, antigen receptors, MHC antigens, adhesion molecules, and cytokine receptors. This FactsBook will be of enormous value to immunologists, cell biologists, biochemists, and endocrinologists.Key Features* Completely up-to-date* Revised and expanded to include over 70 new entries* More than 200 entries in total, plus additional introductory material* New structural data* New nomenclature for CD and related molecules covered

The Immunoglobulin FactsBook
The Immunoglobulin FactsBook

Author: Marie-Paule Lefranc

Publisher: Gulf Professional Publishing

Published: 2001-05-29

Total Pages: 472

ISBN-13: 012441351X

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The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field. The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.

The HLA FactsBook
The HLA FactsBook

Author: Steven G.E. Marsh

Publisher: Elsevier

Published: 1999-12-13

Total Pages: 413

ISBN-13: 0080542506

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The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references

The Nuclear Receptor FactsBook
The Nuclear Receptor FactsBook

Author: Vincent Laudet

Publisher: Elsevier

Published: 2001-10-24

Total Pages: 481

ISBN-13: 0080537804

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The FactsBook Series has established itself as the best source of easily accessible and accurate facts about protein groups. They use an easy-to-follow format and are researched and compiled by experts in the field. This Factsbook is devoted to nuclear receptors. The first section presents an introduction and describes the mode of action of the receptors in general. The second section of the book contains detailed entries covering each type of receptor. - Entries provide information on: Nomenclature and structure, Isolation, DNA binding properties, Ligands, Expression, Target genes, Knockouts, Disease association, Gene structure, promoter and isoforms, Chromosomal location, Amino acid sequences, Key references

The Extracellular Matrix Factsbook
The Extracellular Matrix Factsbook

Author: Shirley Ayad

Publisher: Elsevier

Published: 1998-03-27

Total Pages: 314

ISBN-13: 0080531512

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The Second Edition of The Extracellular Matrix FactsBook has been completely revised, updated and expanded by over 50 percent. It contains over 85 entries on the diverse group of macromolecules that assemble toform the extracellular matrix. Entries provide information on molecular structure, isolation, primary structure, structural and functional sites, gene structure, database accession numbers, and key references.Key Features* Compiled by members of one of the foremost centers of matrix biochemistry in the world* Contains over 30 new entries, with all previous entries being revised and updated* Includes new entries on proteinases involved in the deposition of the extracellular matrix* Presents 3D ribbon diagrams in cases where the protein structure is now known

The Gene Knockout Factsbook, Two-Volume Set
The Gene Knockout Factsbook, Two-Volume Set

Author:

Publisher: Academic Press

Published: 1998-10-26

Total Pages: 1163

ISBN-13: 0080532365

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The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference.Key Features* Entries provide information on:* general description of the protein and its function* gene symbol and database accession number* knockout construct* mouse phenotype* key references

Chemokines and Skin
Chemokines and Skin

Author: Kownatzki

Publisher: Springer

Published: 2012-12-06

Total Pages: 146

ISBN-13: 3034888430

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The present volume summarizes the state of information on chemokines focussing on skin diseases. The first three chapters deal with the structure and molecular biology of chemokines and their receptors. The following three review information on the interaction of chemokines with lymphocytes, mast cells and eosinophilic granulocytes. One chapter deals with the expression of chemokines in several inflammatory skin diseases. The final chapter reports on in vitro evidence for a growth-promoting activity of chemokines in skin-derived tumor cells. The volume is of use for the basic scientist interested in practical aspects and for the physician in search for basic mechanisms of skin diseases.

The T Cell Receptor FactsBook
The T Cell Receptor FactsBook

Author: Marie-Paule Lefranc

Publisher: Elsevier

Published: 2001-07-13

Total Pages: 413

ISBN-13: 0080542646

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The T Cell Receptor FactsBook contains entries on all the 176 functional variable, diversity, joining, and constant regions of the human T cell receptor, including alpha, beta, gamma, and delta loci. Introductory chapters summarize information of T cell receptor chain synthesis, chromosomal location, and an overview of the human T cell receptor loci.