This is the second volume in the series edited by Frank Hartley on The Chemistry of the Metal Carbon Bond. The series is concerned with organometallic compounds from the point of view of the carbon end of the bond and is, therefore, relevant to Organic Chemists. This particular volume is concerned with Carbon-Carbon bonds and their formation using organometallic compounds.
The first book in the PATAI Series was published in 1964 and the Series will celebrate its 50th Anniversary in 2014. This "Golden Jubilee" is accompanied by the publication of the first volume on the chemistry of organogold. In the history of the PATAI Series there was, so far, no volume dedicated to gold alone. In 1999 we published a volume on The Chemistry of Gold and Silver Compounds. Since then a lot of new chemistry using gold has been developed and it is timely to focus a volume on methods and applications of organogold compounds in organic synthesis, reflecting the enormous progress which has been made in the use of gold compounds as reagents and catalysts. A second area of great importance covered in the book is the use of gold surfaces in the synthesis of peptides, proteins and other natural products. A whole range of applications in the area of biochemistry has resulted from these developments. A third area of interest is the synthesis and engineering of nanostructures, where organogold chemistry has opened the door for a wide range of methods and applications in the field of nanoscience and materials science. As with all new volumes, the chapters are first published online in Patai's Chemistry of Functional Groups. Once a volume is completed online, it is then published in print format. The printed book offers the traditional quality of the Patai Book Series, complete with an extensive index.
Part of a multi-volume work within the series "The Chemistry of Functional Groups", this volume covers the chemistry of the metal-carbon bond as a whole, but lays emphasis on the carbon end. It is also concerned with the use of organometallic compounds in organic and biological synthesis. It includes chapters on synthetic techniques such as sonochemistry, photochemistry and phase-transfer catalysis, on synthetic reactions such as asymmetric synthesis, oxidation and metathesis, on synthetic reagents such as metal clusters, organolanthanide, organoantimony and organobismuth reagents and chapters on biological alkylation and bio-organotin compounds.
The first volume of The Chemistry of the Hydrazo, Azo and Azoxy Groups was published in 1975 in two parts, and the present book is the second volume of this publication. Since 1975 three supplementary volumes dealing with the chemistry of double-bonded functional groups were also published in the Series and these volumes contain much material on the chemistry of azoxy compounds. Several subjects were omitted from the original volume in 1975. These omissions have been corrected in the present volume, which contains chapters on "Detection, identification and determination," on NMR, on ESR, on PES, on pharmacology and toxicology, and also on safety and environmental factors.
The occurrence of a wide variety of metal-carbon bonds in living organisms, ranging from bacteria to humans, is only recently recognized. Of course, the historical examples are the B12 coenzymes containing cobalt-carbon bonds, but now such bonds are also known for nickel, iron, copper, and other transition metal ions. There is no other comparable book; MILS-6, written by 17 experts, summarizes the most recent insights into this fascinating topic.
The Chemistry of the Metal-Carbon Bond is a multi-volume work within the well established series of books covering The Chemistry of Functional Groups. It aims to cover the chemistry of the metal-carbon bond as a whole, but lays emphasis on the carbon end. It should therefore be of particular interest to the organic chemist. This fourth volume is concerned with the use of organometallic compounds in organic synthesis. It includes material concerned with carbon-carbon bond formation together with chapters concerned with the formation of carbon-hydrogen and other carbon- element bonds. The material is divided into two parts: the first part is concerned with the preparation of the main group organometallic compounds and their Use in organic synthesis. The second part includes the use of transition metal organometallics in organic synthesis as well as chapters on hydrogenation, saturated carbon-hydrogen bond activation and the rapidly expanding field of supported metal complex catalysts.
This book provides an unparalleled contemporary assessment of hydrocarbon chemistry – presenting basic concepts, current research, and future applications. • Comprehensive and updated review and discussion of the field of hydrocarbon chemistry • Includes literature coverage since the publication of the previous edition • Expands or adds coverage of: carboxylation, sustainable hydrocarbons, extraterrestrial hydrocarbons • Addresses a topic of special relevance in contemporary science, since hydrocarbons play a role as a possible replacement for coal, petroleum oil, and natural gas as well as their environmentally safe use • Reviews of prior edition: “...literature coverage is comprehensive and ideal for quickly reviewing specific topics...of most value to industrial chemists...” (Angewandte Chemie) and “...useful for chemical engineers as well as engineers in the chemical and petrochemical industries.” (Petroleum Science and Technology)
Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.
