Systemic Fibroinflammatory Disorders

Systemic Fibroinflammatory Disorders

Author: Augusto Vaglio

Publisher: Springer

Published: 2017-01-09

Total Pages: 248

ISBN-13: 331941349X

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This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto’s and Riedel’s thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.


IgG4-Related Sclerosing Cholangitis

IgG4-Related Sclerosing Cholangitis

Author: Terumi Kamisawa

Publisher: Springer

Published: 2018-07-31

Total Pages: 141

ISBN-13: 9811045488

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This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.


IgG4-Related Kidney Disease

IgG4-Related Kidney Disease

Author: Takao Saito

Publisher: Springer

Published: 2016-11-09

Total Pages: 298

ISBN-13: 4431556877

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This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.


Diseases of the Brain, Head and Neck, Spine 2020–2023

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author: Juerg Hodler

Publisher: Springer Nature

Published: 2020-02-14

Total Pages: 252

ISBN-13: 303038490X

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This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.


Histiocytic Disorders

Histiocytic Disorders

Author: Oussama Abla

Publisher: Springer

Published: 2017-11-17

Total Pages: 391

ISBN-13: 3319596322

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This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.


Rare and Interesting Cases in Pulmonary Medicine

Rare and Interesting Cases in Pulmonary Medicine

Author: Ali Ataya

Publisher: Academic Press

Published: 2017-02-01

Total Pages: 246

ISBN-13: 0128097671

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Rare and Interesting Cases in Pulmonary Medicine provides a look into the uncommon diseases encountered in the field of pulmonary medicine. Using a case-based approach, the book provides clinical scenarios that include relevant accompanying radiology and pathology. Also included are frequently asked questions for each area, as well as a diagnosis and summary, presenting the reader with the most high yield information on each topic. Appropriate for medical students, residents, fellows, and physicians interested in pulmonary medicine, the case-based approach to each topic allows accessibility to the uncommon diseases of the field while also highlighting high yield and important points. - Provides case-based approaches to the uncommon diseases of pulmonary medicine, including supporting radiology and pathology - Includes uncommon case studies, providing relevant references for further reading and research opportunities - Presents related topics with accompanying clinical pearls for direct application in the field


Diseases of the Abdomen and Pelvis 2018-2021

Diseases of the Abdomen and Pelvis 2018-2021

Author: Juerg Hodler

Publisher: Springer

Published: 2018-03-20

Total Pages: 262

ISBN-13: 3319750194

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This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.


Pediatric Head and Neck Textbook

Pediatric Head and Neck Textbook

Author: Paolo Campisi

Publisher: Springer Nature

Published: 2021-06-17

Total Pages: 783

ISBN-13: 3030592650

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This book focuses on Pediatric Head and Neck Surgical Diseases and Pediatric Surgical Pathology. The core objective is to provide the reader the essential background of various head and neck diseases that are common and/or unique to children by highlighting the key diagnostic, clinical, and pathologic features. It encompasses a comprehensive spectrum of pediatric head and neck diseases that are congenital or acquired. Many chapters describe the clinical and radiologic presentation, age-specific differential diagnosis, and diagnostic histopathologic features. The clinical and pathologic aspects of diseases that are unique to children and young adults that are amenable to surgical care are specifically emphasized. Pediatric Head and Neck Textbook: Pathology, Surgery and Imaging is aimed at trainees and specialists in Pediatrics, Otolaryngology – Head & Neck Surgery, General and Pediatric Surgery, Pediatric Radiology and Pediatric Pathology.


Clinical Oral Medicine and Pathology

Clinical Oral Medicine and Pathology

Author: Jean M. Bruch

Publisher: Springer Science & Business Media

Published: 2009-11-11

Total Pages: 176

ISBN-13: 1603275207

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Clinical Oral Medicine and Pathology, is a clinically relevant and accessible resource for health care professionals that truly bridges the worlds of dentistry and medicine. This handbook of oral medicine and oral pathology serves as a highly readable guide for diagnosis and treatment of commonly encountered oral conditions. The volume is organized by grouping clinical entities under easily recognizable, diagnostically related headings and subheadings and allows the busy clinician to quickly reference and identify a lesion of interest. Concise descriptions of each entity provide background information and treatment recommendations while including specific guidelines on diagnosis, management, and follow-up. The authors of this text both have extensive training in the fields of oral pathology, dentistry, oral surgery and otolaryngology, and provide a comprehensive approach to the practice of oral medicine for all those who are likely to encounter diseases of the oral cavity in their daily practice.