Systemic Amyloidosis due to Monoclonal Immunoglobulins, An Issue of Hematology/Oncology Clinics of North America, E-Book
Systemic Amyloidosis due to Monoclonal Immunoglobulins, An Issue of Hematology/Oncology Clinics of North America, E-Book

Author: Raymond L. Comenzo

Publisher: Elsevier Health Sciences

Published: 2020-10-28

Total Pages: 241

ISBN-13: 0323791662

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This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Raymond L. Comenzo, is devoted to Systemic Amyloidosis due to Monoclonal Immunoglobulins. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: The Spectrum of Monoclonal Immunoglobulin Diseases, Systemic Amyloidosis due to Clonal Plasma Cell Diseases, Systemic Amyloidosis due to Low-grade Lymphomas, The Process of Amyloid Formation due to Monoclonal Immunoglobulins, Cardiac Involvement, Renal Involvement, Liver and Gastrointestinal Involvement, Peripheral Nervous System Involvement, Options for Chemotherapy, Stem-cell Mobilization and Autologous Transplant, Monoclonal Antibody Therapies, Solid Organ Transplant, Supportive Care, Patient Voices, and Future Perspectives.

Amyloid and Related Disorders
Amyloid and Related Disorders

Author: Maria M. Picken

Publisher: Humana Press

Published: 2015-08-17

Total Pages: 536

ISBN-13: 3319192949

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The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.

Cancer and the Kidney
Cancer and the Kidney

Author: Eric P. Cohen

Publisher: Oxford University Press, USA

Published: 2010-11-11

Total Pages: 382

ISBN-13: 0199580197

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Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.

Bancroft's Theory and Practice of Histological Techniques E-Book
Bancroft's Theory and Practice of Histological Techniques E-Book

Author: Kim S Suvarna

Publisher: Elsevier Health Sciences

Published: 2012-10-01

Total Pages: 655

ISBN-13: 0702050326

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This is a brand new edition of the leading reference work on histological techniques. It is an essential and invaluable resource suited to all those involved with histological preparations and applications, from the student to the highly experienced laboratory professional. This is a one stop reference book that the trainee histotechnologist can purchase at the beginning of his career and which will remain valuable to him as he increasingly gains experience in daily practice. Thoroughly revised and up-dated edition of the standard reference work in histotechnology that successfully integrates both theory and practice.Provides a single comprehensive resource on the tried and tested investigative techniques as well as coverage of the latest technical developments. Over 30 international expert contributors all of whom are involved in teaching, research and practice.Provides authoritative guidance on principles and practice of fixation and staining. Extensive use of summary tables, charts and boxes.Information is well set out and easy to retrieve. Six useful appendices included (SI units, solution preparation, specimen mounting, solubility). Provides practical information on measurements, preparation solutions that are used in daily laboratory practice. Color photomicrographs used extensively throughout. Better replicates the actual appearance of the specimen under the microscope. Brand new co-editors. New material on immunohistochemical and molecular diagnostic techniques.Enables user to keep abreast of latest advances in the field.

Systemic Amyloidosis Due to Monoclonal Immunoglobulins, an Issue of Hematology/Oncology Clinics of North America, Volume 34-6
Systemic Amyloidosis Due to Monoclonal Immunoglobulins, an Issue of Hematology/Oncology Clinics of North America, Volume 34-6

Author: Raymond L. Comenzo

Publisher: Elsevier

Published: 2020-12-28

Total Pages: 240

ISBN-13: 9780323791656

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This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Raymond L. Comenzo, is devoted to Systemic Amyloidosis due to Monoclonal Immunoglobulins. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: The Spectrum of Monoclonal Immunoglobulin Diseases, Systemic Amyloidosis due to Clonal Plasma Cell Diseases, Systemic Amyloidosis due to Low-grade Lymphomas, The Process of Amyloid Formation due to Monoclonal Immunoglobulins, Cardiac Involvement, Renal Involvement, Liver and Gastrointestinal Involvement, Peripheral Nervous System Involvement, Options for Chemotherapy, Stem-cell Mobilization and Autologous Transplant, Monoclonal Antibody Therapies, Solid Organ Transplant, Supportive Care, Patient Voices, and Future Perspectives.

WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

Author: E. Campo

Publisher: IARC Who Classification of Tum

Published: 2017-09-18

Total Pages: 586

ISBN-13: 9789283244943

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WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues is a Revised Fourth Edition of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants further include new ICD-O codes, epidemiology, clinical features, macroscopy, prognosis, and predictive factors. This classification, prepared by 132 authors from 23 countries, contains about 1300 color images and tables and more than 4500 references.

The Kidney in Plasma Cell Dyscrasias
The Kidney in Plasma Cell Dyscrasias

Author: Guillermo A. Herrera

Publisher: Karger Medical and Scientific Publishers

Published: 2007

Total Pages: 223

ISBN-13: 3805581785

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In recent years, the knowledge of how renal damage occurs in patients with plasma cell dyscrasias / myeloma has substantially increased. For the first time, this publication brings together issues relating to the diagnosis and pathogenesis of these disorders, as well as a summary of advances achieved in the treatment and management of patients. Several chapters are devoted to various glomerulopathies associated with deposition of immunoglobulin light and heavy chains, including those associated with amyloidosis. The sequential events are pointed out, crucial steps and key molecules open to modulation or control are delineated, and therapeutic advances are highlighted. Although the emphasis is on the management of cases with renal involvement, a distinct focus on the diseases as a whole and their impact on patients' general health and prognosis has been maintained throughout the discussions. Using a translational approach to renal manifestations in patients with plasma cell dyscrasias / myelomas, this publication conveys a comprehensive state-of-the-art view of the subject. It is aimed at practicing renal pathologists, nephrologists, internists and hematologists, as well as at trainees and scientists working in these specialties.

Williams Hematology, 10th Edition
Williams Hematology, 10th Edition

Author: Kenneth Kaushansky

Publisher: McGraw Hill Professional

Published: 2021-01-14

Total Pages: 2705

ISBN-13: 126046413X

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The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of basic science and translational pathophysiology for optimal, lifelong learning. Experts in research and clinical hematology, the editors are known worldwide for their contributions to the field. This new edition contains everything that has made Williams Hematology the go-to resource for decades and has been updated with new chapters and critical new research into the molecular mechanisms responsible for hematological disorders and the impact on diagnosis and treatment. And the new format enables you to access each chapter via content modules covering key topics, with summaries, infographics, and cases―all linked to review questions for self-assessment. The full-color presentation integrates images of blood and tissue findings where they are cited in the text. NEW TO THIS EDITION: Updated and revised content reflecting the latest research and developments Convenient format that streamlines the learning process and improves retention Additional chapters added on: Immune Checkpoint Inhibitors Immune Cell Therapy: Chimeric Antigen Receptor T Cell Therapy Immune Cell Therapy Dendritic Cell and Natural Killer Cell Therapy The processes of cell death and survival Application of Big Data and Deep Learning in Hematology Williams Hematology Cases with multiple-choice questions including detailed explanations—perfect preparation for the boards Continuously updated online content with comprehensive drug therapy database and other resources

Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues
Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

Author: World Health Organization

Publisher: IARC

Published: 2001

Total Pages: 360

ISBN-13: 9789283224112

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This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.

Multiple Myeloma and Other Plasma Cell Neoplasms
Multiple Myeloma and Other Plasma Cell Neoplasms

Author: Meletios A. Dimopoulos

Publisher: Springer

Published: 2018-02-16

Total Pages: 247

ISBN-13: 331925586X

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This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.