Systematic

Systematic

Author: James R. Valcourt

Publisher: Bloomsbury Publishing USA

Published: 2017-02-07

Total Pages: 289

ISBN-13: 1632860317

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A brilliant young scientist introduces us to the fascinating field that is changing our understanding of how the body works and the way we can approach healing. SYSTEMATIC is the first book to introduce general readers to systems biology, which is improving medical treatments and our understanding of living things. In traditional bottom-up biology, a biologist might spend years studying how a single protein works, but systems biology studies how networks of those proteins work together--how they promote health and how to remedy the situation when the system isn't functioning properly. Breakthroughs in systems biology became possible only when powerful computer technology enabled researchers to process massive amounts of data to study complete systems, and has led to progress in the study of gene regulation and inheritance, cancer drugs personalized to an individual's genetically unique tumor, insights into how the brain works, and the discovery that the bacteria and other microbes that live in the gut may drive malnutrition and obesity. Systems biology is allowing us to understand more complex phenomena than ever before. In accessible prose, SYSTEMATIC sheds light not only on how systems within the body work, but also on how research is yielding new kinds of remedies that enhance and harness the body's own defenses.


Assembling the Pieces of a Systematic Review

Assembling the Pieces of a Systematic Review

Author: Margaret J. Foster

Publisher: Rowman & Littlefield

Published: 2017-03-03

Total Pages: 243

ISBN-13: 1442277025

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Here is a complete guide for librarians seeking to launch or refine their systematic review services. Conducting searches for systematic reviews goes beyond expert searching and requires an understanding of the entire process of the systematic review. Just as expert searching is not fully mastered by the end of a library degree, mastering the systematic review process takes a great deal of time and practice. Attending workshops and webinars can introduce the topic, but application of the knowledge through practice is required. Running a systematic review service is complicated and requires constant updating and evaluation with new standards, more efficient methods, and improved reporting guidelines. After a brief introduction to systematic reviews, the book guides librarians in defining and marketing their services, covering topics such as when it is appropriate to ask for co-authorship and how to reach out to stakeholders. Next, it addresses developing documentation and conducting the reference interview. Standards specific to systematic reviews, including PRISMA, Institute of Medicine, and Cochrane Collaboration, are discussed. Search strategy techniques, including choosing databases, harvesting search terms, selecting filters, and searching for grey literature are detailed. Data management and critical appraisal are covered in detail. Finally, the best practices for reporting the findings of systematic reviews are highlighted. Experts with experience in both systematic reviews and librarianship, including the editors of the book, contributed to the chapters. Each step (or piece) of the review process (Planning the review, Identifying the studies, Evaluating studies, Collecting and combining data, Explaining the results, and Summarizing the review into a report), are covered with emphasis on information roles. The book is for any librarian interested in conducting reviews or assisting others with reviews. It has several applications: for training librarians new to systematic reviews, for those developing a new systematic review service, for those wanting to establish protocols for a current service, and as a reference for those conducting reviews or running a service. Participating in systematic reviews is a new frontier of librarianship, in which librarians can truly become research partners with our patrons, instead of merely providing access to resources and services.


Cochrane Handbook for Systematic Reviews of Interventions

Cochrane Handbook for Systematic Reviews of Interventions

Author: Julian P. T. Higgins

Publisher: Wiley

Published: 2008-11-24

Total Pages: 672

ISBN-13: 9780470699515

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Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.


An Introduction to Systematic Reviews

An Introduction to Systematic Reviews

Author: David Gough

Publisher: SAGE

Published: 2012-03-22

Total Pages: 382

ISBN-13: 1446289362

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This timely, engaging book provides an overview of the nature, logic, diversity and process of undertaking systematic reviews as part of evidence informed decision making. A focused, accessible and technically up-to-date book, it covers the full breadth of approaches to reviews from statistical meta analysis to meta ethnography. It is ideal for anyone undertaking their own systematic review - providing all the necessary conceptual and technical background needed to make a good start on the process. The content is divided into five clear sections: • Approaches to reviewing • Getting started • Gathering and describing research • Appraising and synthesising data • Making use of reviews/models of research use. Easy to read and logically structured, this book is essential reading for anyone doing systematic reviews. David Gough is Professor of Evidence Informed Policy and Practice and Director of SSRU and its EPPI-Centre and Co-Editor of the journal Evidence & Policy. Sandy Oliver is Professor of Public Policy and Deputy Director of SSRU and its EPPI-Centre. James Thomas is Reader in Social Policy, Assistant Director of SSRU and Associate Direcctor of the EPPI-Centre.


Systematic Searching

Systematic Searching

Author: Paul Levay

Publisher: Facet Publishing

Published: 2019-01-15

Total Pages: 352

ISBN-13: 1783303735

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In resource poor, cost saving times, this book provides practical advice on new methods and technologies involved in systematic searching and explores the role of information professionals in delivering these changes The editors bring together expert international practitioners and researchers to highlight the latest thinking on systematic searching. Beginning by looking at the methods and techniques underlying systematic searching, the book then examines the current challenges and the potential solutions to more effective searching in detail, before considering the role of the information specialist as an expert searcher. Systematic Searching blends theory and practice and takes into account different approaches to information retrieval with a special focus being given to searching for complex topics in a health-related environment. The book does not presume an in-depth prior knowledge or experience of systematic searching and includes case studies, practical examples and ideas for further research and reading. The book is divided into three parts: Methods covers theoretical approaches to evidence synthesis and the implications that these have for the search process, including searching for complex topics and choosing the right sources. Technology examines new technologies for retrieving evidence and how these are leading to new directions in information retrieval and evidence synthesis. People considers the future of the information specialist as an expert searcher and explores how information professionals can develop their skills in searching, communication and collaboration to ensure that information retrieval practice is, and remains, evidence-based. Systematic Searching will be essential reading for library and information service providers and information specialists, particularly those in a health-related environment. It will also be of interest to students of library and information science, systematic reviewers, researchers and practitioners conducting complex searches in settings including social care, education and criminal justice.


Work Design

Work Design

Author: Adedeji B. Badiru

Publisher: CRC Press

Published: 2017-07-12

Total Pages: 314

ISBN-13: 1498755747

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Work is all around us and permeates everything we do and everyday activities. Not all work is justified, not all work is properly designed, or evaluated accurately, or integrated. A systems model will make work more achievable through better management. Work is defined as a process of performing a defined task or activity, such as research, development, operations, maintenance, repair, assembly, production, and so on. Very little is written on how to design, evaluate, justify, and integrate work. Using a comprehensive systems approach, this book facilitates a better understanding of work for the purpose of making it more effective and rewarding.


Systematic Data Collection

Systematic Data Collection

Author: Susan C. Weller

Publisher: SAGE Publications

Published: 1988-02-01

Total Pages: 110

ISBN-13: 1506349757

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The process of collecting accurate data through interviewing, questionnaires, and other methods has not always been clear. However, data collection in field settings can be done in a structured, systematic and scientific way. These authors show us how. First, they focus on the importance of finding the right questions to ask. By providing a variety of formats - triadic comparisons and rating scales for data collection, both oral and written methods - and stressing cultural relativity, Weller and Romney suggest ways to improve not only the data collected, but also the interpretation and analysis of such data. Primarily addressed to qualitative social scientists, this volume is also appropriate for anyone who wants to study attitudes and beliefs. In particular, it is an ideal text for courses in anthropology, linguistics, qualitative research methods, health care, and survey research.


Finding What Works in Health Care

Finding What Works in Health Care

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-07-20

Total Pages: 267

ISBN-13: 0309164257

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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.


Systematic Reviews in Health Care

Systematic Reviews in Health Care

Author: Matthias Egger

Publisher: John Wiley & Sons

Published: 2008-04-15

Total Pages: 512

ISBN-13: 0470693142

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The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.


Systematic Trading

Systematic Trading

Author: Robert Carver

Publisher: Harriman House Limited

Published: 2015-09-14

Total Pages: 247

ISBN-13: 085719500X

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This is not just another book with yet another trading system. This is a complete guide to developing your own systems to help you make and execute trading and investing decisions. It is intended for everyone who wishes to systematise their financial decision making, either completely or to some degree. Author Robert Carver draws on financial theory, his experience managing systematic hedge fund strategies and his own in-depth research to explain why systematic trading makes sense and demonstrates how it can be done safely and profitably. Every aspect, from creating trading rules to position sizing, is thoroughly explained. The framework described here can be used with all assets, including equities, bonds, forex and commodities. There is no magic formula that will guarantee success, but cutting out simple mistakes will improve your performance. You'll learn how to avoid common pitfalls such as over-complicating your strategy, being too optimistic about likely returns, taking excessive risks and trading too frequently. Important features include: - The theory behind systematic trading: why and when it works, and when it doesn't. - Simple and effective ways to design effective strategies. - A complete position management framework which can be adapted for your needs. - How fully systematic traders can create or adapt trading rules to forecast prices. - Making discretionary trading decisions within a systematic framework for position management. - Why traditional long only investors should use systems to ensure proper diversification, and avoid costly and unnecessary portfolio churn. - Adapting strategies depending on the cost of trading and how much capital is being used. - Practical examples from UK, US and international markets showing how the framework can be used. Systematic Trading is detailed, comprehensive and full of practical advice. It provides a unique new approach to system development and a must for anyone considering using systems to make some, or all, of their investment decisions.