Beauty in Chemistry
Beauty in Chemistry

Author: Luigi Fabbrizzi

Publisher: Springer Science & Business Media

Published: 2012-02-22

Total Pages: 180

ISBN-13: 3642283411

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The Beauty of Chemistry in the Words of Writers and in the Hands of Scientists, by Margherita Venturi, Enrico Marchi und Vincenzo Balzani Living in a Cage Is a Restricted Privilege, by Luigi Fabbrizzi Inner and Outer Beauty, by Kenneth N. Raymond und Casey J. Brown The Mechanical Bond: A Work of Art, by Carson J. Bruns und J. Fraser Stoddart The Beauty of Knots at the Molecular Level, by Jean-Pierre Sauvage und David B. Amabilino

Bioassay Techniques for Drug Development
Bioassay Techniques for Drug Development

Author: Atta-ur-Rahman

Publisher: CRC Press

Published: 2001-10-04

Total Pages: 214

ISBN-13: 1135287228

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The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa

Lanthanide Single Molecule Magnets
Lanthanide Single Molecule Magnets

Author: Jinkui Tang

Publisher: Springer

Published: 2015-04-24

Total Pages: 219

ISBN-13: 3662469995

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This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures – an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and explore new directions. Jinkui Tang is a professor at Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. Peng Zhang is currently pursuing his PhD at Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, with a specific focus on the molecular magnetism of lanthanide compounds under the supervision of Prof. Jinkui Tang.

Metal Complex - DNA Interactions
Metal Complex - DNA Interactions

Author: Nick Hadjiliadis

Publisher: John Wiley & Sons

Published: 2009-03-30

Total Pages: 544

ISBN-13: 9781405194105

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Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.

A Search for Antibacterial Agents
A Search for Antibacterial Agents

Author: Varaprasad Bobbarala

Publisher: BoD – Books on Demand

Published: 2012-09-19

Total Pages: 358

ISBN-13: 9535107240

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This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Research Methodology in Chemical Sciences
Research Methodology in Chemical Sciences

Author: Tanmoy Chakraborty

Publisher: CRC Press

Published: 2017-03-03

Total Pages: 388

ISBN-13: 149872860X

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Recent Methodology in Chemical Sciences provides an eclectic survey of contemporary problems in experimental, theoretical, and applied chemistry. This book covers recent trends in research with the different domain of the chemical sciences. The chapters, written by knowledgeable researchers, provide different insights to the modern-day research in the domain of spectroscopy, plasma modification, and theoretical and computational analysis of chemical problems. It covers descriptions of experimental techniques, discussions on theoretical modeling, and much more.

Cadmium: From Toxicity to Essentiality
Cadmium: From Toxicity to Essentiality

Author: Astrid Sigel

Publisher: Springer Science & Business Media

Published: 2013-02-26

Total Pages: 590

ISBN-13: 9400751796

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Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.

Cage Metal Complexes
Cage Metal Complexes

Author: Yan Voloshin

Publisher: Springer

Published: 2017-05-11

Total Pages: 475

ISBN-13: 331956420X

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This fundamental book presents the most comprehensive summary of the current state in chemistry of cage metal complexes. After their previous book “The Encapsulation Phenomenon” (www.springer.com/978-3-319-27737-0) the authors in this book focus on the encapsulation of metal ions by different types of three-dimensional mono- and polynucleating caging ligands. Within these cage metal complexes, (metal) ions can be isolated from external factors. The book provides both a classification of the cage compounds and summaries of synthetic approaches. On that basis the authors then describe the unique chemical and physical properties and the resulting reactivity of the cage compounds, as well as practical and potential applications as potent topological drugs and prodrugs, antifibrillogenic agents, radiodiagnostic and radiotherapeutic compounds, paramagnetic probes, single-molecule magnets, electrocatalysts for hydrogen production, (photo)electronic devices, and many more. Readers will find a well-structured and concise overview, with particular emphasis on a review of synthesis and reactivity of various cage metal complexes, summarizing over 400 literature references, clearly presented in over 300 color schemes and figures.

Comprehensive Coordination Chemistry II
Comprehensive Coordination Chemistry II

Author: J. A. McCleverty

Publisher: Newnes

Published: 2003-12-03

Total Pages: 11845

ISBN-13: 0080913164

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Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.