Read and Download eBook Full
Author: Xinyi Zhang
Publisher:
Published: 2018
Total Pages: 526
ISBN-13: 9789813227668
DOWNLOAD EBOOK"The book contains the latest synchrotron-based techniques and research results. All contributors are specialists or leading scientists in their fields. The book includes new techniques and methods that will potentially get wider applications in various disciplines"--
Author: R. Sweet
Publisher: Springer Science & Business Media
Published: 2013-03-09
Total Pages: 354
ISBN-13: 1468480413
DOWNLOAD EBOOKThe development of synchrotron radiation (SR) as a research tool was driven largely by the needs of materials scientists and solid-state physi cists. However, the availability of SR has extended significantly the capa bility of scientists who study biological structure with radiation. This volume contains some of the results reported at a symposium held at Brookhaven National Laboratory in May 1988 to discuss the application of synchrotron radiation to structural biology. We are grateful for financial support from the u. s. Department of Energy, the National Institutes of Health, Genentech, Inc., Blake Indus tries, Inc., Evans and Sutherland Co., The Upjohn Company, Eli Lilly and Company, Enraf-Nonius Service Corp., and Associated Universities, Inc. We warmly thank Ms. Nancy Siemon for her tireless efforts with correspondence and the manuscripts for this symposium volume. Symposium Committee: Robert M. Sweet, Chair Malcolm S. Capel Benno P. Schoenborn John C. Sutherland Elizabeth C. Theil Stephen W. White Avril D. Woodhead Helen Z. Kondratuk, Coordinator v CONTENTS An Introduction to the Symposium . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 R. M. Sweet SYMPOSIUM LECTURE Developments in X-ray Technology and Their Contribution to Structural Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 H. E. Huxley SOME OF THE SYNCHROTRON FACILITIES FOR BIOLOGICAL STRUCTURAL STUDIES MacChess - A Macromolecular Diffraction Resource at the Cornell High Energy Synchrotron Source . . . . . . . . . . . . . . . . . . . 15 W. Schi1dkamp, K. Moffat, B. Batterman, D. Bilderback, T-Y. Teng, A. LeGrand and D. Szebenyi Facilities Available for Biophysics Research at the Stanford Synchrotron Radiation Laboratory. . . . . . . . . . . . . . . . . . . . . 19 R. P."
Author: R. Sweet
Publisher:
Published: 2014-09-01
Total Pages: 376
ISBN-13: 9781468480429
DOWNLOAD EBOOKAuthor: Brookhaven National Laboratory
Publisher: Springer
Published: 1989-09
Total Pages: 384
ISBN-13:
DOWNLOAD EBOOKProceedings of the symposium held in Upton, NY, May 22-25 1988. General topics in x-ray research include: small angle scattering, crystallography, spectroscopy, advances in instrumentation, and new methods. Annotation copyright Book News, Inc. Portland, Or.
Author: Bonnie Ann Wallace
Publisher: IOS Press
Published: 2009
Total Pages: 244
ISBN-13: 1607500000
DOWNLOAD EBOOKPresents an account of circular dichroism (CD) spectroscopy and its application to structural biology. This book covers the methods of synchrotron radiation circular dichroism (SRCD) and linear dichroism (LD).
Author: Eugenia Pechkova
Publisher: CRC Press
Published: 2011-11-11
Total Pages: 514
ISBN-13: 9814267937
DOWNLOAD EBOOKThis book presents an overview of the current state of research in both synchrotron radiation and structural proteomics from different laboratories worldwide. The book presents recent research results in the most advanced methods of synchrotron radiation analysis, protein micro- and nano crystallography, X-ray scattering and X-ray optics, coherent
Author: Dava Sobel
Publisher: Bloomsbury Publishing USA
Published: 2010-07-05
Total Pages: 209
ISBN-13: 0802779433
DOWNLOAD EBOOKThe dramatic human story of an epic scientific quest and of one man's forty-year obsession to find a solution to the thorniest scientific dilemma of the day--"the longitude problem." Anyone alive in the eighteenth century would have known that "the longitude problem" was the thorniest scientific dilemma of the day-and had been for centuries. Lacking the ability to measure their longitude, sailors throughout the great ages of exploration had been literally lost at sea as soon as they lost sight of land. Thousands of lives and the increasing fortunes of nations hung on a resolution. One man, John Harrison, in complete opposition to the scientific community, dared to imagine a mechanical solution-a clock that would keep precise time at sea, something no clock had ever been able to do on land. Longitude is the dramatic human story of an epic scientific quest and of Harrison's forty-year obsession with building his perfect timekeeper, known today as the chronometer. Full of heroism and chicanery, it is also a fascinating brief history of astronomy, navigation, and clockmaking, and opens a new window on our world.
Author: Chunhai Fan
Publisher: John Wiley & Sons
Published: 2018-05-29
Total Pages: 846
ISBN-13: 3527339868
DOWNLOAD EBOOKMeeting the long-felt need for in-depth information on one of the most advanced material characterization methods, a top team of editors and authors from highly prestigious facilities and institutions covers a range of synchrotron techniques that have proven useful for materials research. Following an introduction to synchrotron radiation and its sources, the second part goes on to describe the various techniques that benefit from this especially bright light, including X-ray absorption, diffraction, scattering, imaging, and lithography. The thrid and final part provides an overview of the applications of synchrotron radiation in materials science. bridging the gap between specialists in synchrotron research and material scientists, this is a unique and indispensable resource for academic and industrial researchers alike.
Author: Jean-Paul Renaud
Publisher: John Wiley & Sons
Published: 2020-01-09
Total Pages: 1437
ISBN-13: 1118900502
DOWNLOAD EBOOKWith the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Author: H. Saisho
Publisher: Elsevier
Published: 1996-08-02
Total Pages: 511
ISBN-13: 0080527418
DOWNLOAD EBOOKSynchroton radiation (SR) is utilized in most scientific fields. This book will therefore be useful not only for researchers engaged in analytical chemistry, and those studying the basic fields such as physics, chemistry, biology, as well as earth science, medicine, and life science but also for those engaged in research for elucidating structure of material and its function in the application fields including applied physics, semiconductor engineering, and metal engineering. The book has a highly interdisciplinary character. The outstanding characteristics of SR have also contributed to the rapid development of new fields and applications in analytical chemistry.Features of this book:• Explains the basics of SR• Facilities and instrumentation are covered to facilitate the planning of experiments using SR.• Aspects for the future development of SR are included together with an introduction to the latest techniques which are expected to find increasing use in the coming years.This book should stimulate students specializing in analytical chemistry and materials science to have an interest in SR. In addition, it will provide scientists who are beginning analytical chemistry research using SR with instructive and illustrative descriptions. The book can also be used as an explanatory text for advanced research on the application of SR.
