Synaptic Resurgence
Synaptic Resurgence

Author: Rick Anthony

Publisher: Rick Anthony

Published: 2023-06-13

Total Pages: 119

ISBN-13:

DOWNLOAD EBOOK

In a world teetering on the edge of collapse, where power is concentrated in the hands of the few and humanity is at the mercy of manipulative forces, "Synaptic Resurgence" invites you on an exhilarating journey into a future transformed by advanced neural technology and the unyielding spirit of resistance. In this gripping sci-fi thriller, we follow the remarkable journey of Emma Collins, a brilliant neuroscientist haunted by a tragic past. The discovery of a revolutionary neural implant called the "Synapse X" unveils a realm of possibilities—a seamless connection between human minds and artificial intelligence that promises to enhance cognitive abilities beyond imagination. But the true potential of this groundbreaking technology reaches far beyond mere augmentation. As governments, corporations, and underground organizations vie for control over the immense power of the Synapse X, Emma finds herself thrust into a perilous game of cat and mouse. Betrayed by those she thought she could trust, she must navigate a treacherous landscape of intrigue and deceit to evade capture and uncover the truth. Along the way, she forges an unlikely alliance with a rogue hacker and a group of rebels fighting against the oppressive forces seeking to harness the implant's power for their own gain.

Physiology of Neurons
Physiology of Neurons

Author: Anne Feltz

Publisher: Garland Science

Published: 2020-03-25

Total Pages: 479

ISBN-13: 1000761398

DOWNLOAD EBOOK

Thanks to tremendous technical advances in molecular biology and cellular imaging after those in electrophysiology, there is now a deep understanding of the physiology of nerve cells and their synaptic interconnections. The complexity of the brain emerges from the communication and interaction between billions of these elements. This book explores systematically and didactically the details of neuronal physiology, covering membrane biophysics, receptor physiology, sensory transduction and synaptic transmission with its selective pharmacology. Readers of the book will be fully equipped to understand the functions and possibilities of the key units of the brain’s parallel computations.

Microstructural Parcellation of the Human Cerebral Cortex
Microstructural Parcellation of the Human Cerebral Cortex

Author: Stefan Geyer

Publisher: Springer Science & Business Media

Published: 2013-07-04

Total Pages: 260

ISBN-13: 3642378242

DOWNLOAD EBOOK

Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.

Jasper's Basic Mechanisms of the Epilepsies
Jasper's Basic Mechanisms of the Epilepsies

Author: Jeffrey Noebels

Publisher: OUP USA

Published: 2012-06-29

Total Pages: 1258

ISBN-13: 0199746540

DOWNLOAD EBOOK

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Cellular Electron Microscopy
Cellular Electron Microscopy

Author: J. Richard McIntosh

Publisher: Elsevier

Published: 2011-09-02

Total Pages: 878

ISBN-13: 0080475035

DOWNLOAD EBOOK

Recent advances in the imaging technique electron microscopy (EM) have improved the method, making it more reliable and rewarding, particularly in its description of three-dimensional detail. Cellular Electron Microscopy will help biologists from many disciplines understand modern EM and the value it might bring to their own work. The book's five sections deal with all major issues in EM of cells: specimen preparation, imaging in 3-D, imaging and understanding frozen-hydrated samples, labeling macromolecules, and analyzing EM data. Each chapter was written by scientists who are among the best in their field, and some chapters provide multiple points of view on the issues they discuss. Each section of the book is preceded by an introduction, which should help newcomers understand the subject. The book shows why many biologists believe that modern EM will forge the link between light microscopy of live cells and atomic resolution studies of isolated macromolecules, helping us toward the goal of an atomic resolution understanding of living systems. - Updates the numerous technological innovations that have improved the capabilities of electron microscopy - Provides timely coverage of the subject given the significant rise in the number of biologists using light microscopy to answer their questions and the natural limitations of this kind of imaging - Chapters include a balance of "how to", "so what" and "where next", providing the reader with both practical information, which is necessary to use these methods, and a sense of where the field is going

Mitochondrial Dynamics and Neurodegeneration
Mitochondrial Dynamics and Neurodegeneration

Author: Bingwei Lu

Publisher: Springer Science & Business Media

Published: 2011-05-16

Total Pages: 271

ISBN-13: 940071291X

DOWNLOAD EBOOK

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Computational Intelligence. Theory and Applications
Computational Intelligence. Theory and Applications

Author: Bernd Reusch

Publisher: Springer Science & Business Media

Published: 1997-04-16

Total Pages: 632

ISBN-13: 9783540628682

DOWNLOAD EBOOK

This book constitutes the refereed proceedings of the International Conference on Computational Intelligence held in Dortmund, Germany, as the 5th Fuzzy Days, in April 1997. Besides three invited contributions, the book presents 53 revised full papers selected from a total of 130 submissions. Also included are 35 posters documenting a broad scope of applications of computational intelligence techniques in a variety of areas. The volume addresses all current issues in computational intelligence, e.g. fuzzy logic, fuzzy control, neural networks, evolutionary algorithms, genetic programming, neuro-fuzzy systems, adaptation and learning, machine learning, etc.

Co-Existence and Co-Release of Classical Neurotransmitters
Co-Existence and Co-Release of Classical Neurotransmitters

Author: Rafael Gutierrez

Publisher: Springer Science & Business Media

Published: 2008-12-16

Total Pages: 277

ISBN-13: 0387096221

DOWNLOAD EBOOK

Dale's Principle postulated that a neuron functions as a metabolic unit, whereby a process occurring in the cell can influence all of the compartments of that given neuron. This was unfortunately transformed in the literature to a principle stating that “a single cell releases only one neurotransmitter”. Until recently, this has influenced many neuroscientists to consider with skepticism the idea that classical neurotransmitters could be co-released from neurons. It is now clear that the “one neuron, one neurotransmitter” postulate is the exception rather than the rule. The aim of this book is to gather the available evidence, provided by the authors that have discovered and studied the co-existence or co-release of several pairs of neurotransmitters, in several neural networks. It will provide a timely overview of a mechanism of neural communication that is likely to attract increasing attention of the neuroscientific community.

Mechanistic Relationships Between Development and Learning
Mechanistic Relationships Between Development and Learning

Author: Thomas J. Carew

Publisher: John Wiley & Sons

Published: 1998-06-29

Total Pages: 346

ISBN-13: 9780471977025

DOWNLOAD EBOOK

At the turn of the century, the pioneering neuroscientist Ramon y Cajal articulated the hypothesis that growth processes involved in the development of the central nervous system may persist into adulthood, where they might be retained to mediate the formation and maintenance of memory. Over the decades since Cajal s seminal suggestion, extensive experimental attention has been directed at elucidating the cellular and molecular mechanisms underlying both neuronal development and learning and memory. Many exciting technical and conceptual advances have been made on each front. Thus, as we approach the end of this century, the field is now poised to assess the status of Cajal s provocative hypothesis directly. This volume reflects a highly interdisciplinary dialog among experts in the fields of development and learning and memory, who came together not only to assess the validity of the general hypotheses that development and learning might share mechanistic features, but also to identify issues, preparations, and paradigms that would allow for a rigorous evaluation of ways to advance the hypothesis, on the one hand, and determine its fundamental limitations, on the other. Towards this end, the volume is organized into four levels of analysis: behavioral, systems, cellular, and molecular. At each level, neuroscientists from the general fields of development and learning engage in lively exchange of ideas which serve to highlight the similarities and differences of both the concepts and the experimental approaches used in their diverse fields. The result of this endeavor is a collection of seminal chapters and summary reports that provide a novel synthesis of important advances in two exciting areas of modern neuroscience. Goal of this Dahlem Workshop: to evaluate the validity of the general thesis that mechanisms utilized in the development of the nervous system are reutilized in the adult to mediate formation and maintenance of memory.