Symposium on Biophysics and Physiology of Biological Transport
Symposium on Biophysics and Physiology of Biological Transport

Author: Liana Bolis

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 350

ISBN-13: 3709155770

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The study of cell membranes began to attract increasing interest before the turn of the present century with the observations of 0 verton. Since that time many investigators have become interested in the broad problem of structure and function of the membrane and today we find ourselVes at a stage in which several branches of research, particularly physical chemistry, biochemistry, biophysics, physiology and pharmacology have come together, leading to the possibility of obtaining a better perspective of the overall problems. The purpose of this Symposium was to assemble in an orderly sequence representations of the knowledge of membranes achieved to date in the areas of the various disciplines. It was thought that to bring together many points of view on a problem should allow the conferees to see better what had been accomplished, what has been overlooked and what needs further development. It is to be hoped that efforts of this type have and will fulfill the desired purpose. This volume contains the majority of the papers contributed by the participants in the Symposium. In addition, it seemed logical to place at the beginning of each chapter at least one general survey of the subject which would help those who were less acquainted with the problem to derive the most benefit from their reading.

Current Catalog
Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published: 1993

Total Pages: 1628

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.

Concepts in Biochemical Pharmacology
Concepts in Biochemical Pharmacology

Author: H.S. Ackermann

Publisher: Springer Science & Business Media

Published: 2013-11-27

Total Pages: 486

ISBN-13: 364265052X

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This volume of the Handbook of Experimental Pharmacology (Concepts in Biochemical Pharmacology) will show that pharma cology has finally arrived as a true discipline in its own right, and is no longer the handmaiden of organic chemistry and physiology. Instead it is an amalgam of all the biological sciences including biochemistry, biophysical chemistry, physiology, pathology and clinical medicine. In the volumes that make up Concepts in Bioche mical Pharmacology we hope to convince Medical Schools what should now be obvious, that pharmacology is no longer that dull topic bridging the basic sciences with medicine, but is probably the most important subject in the medical curriculum. We are grateful for the advice of Dr. BYRON CLARKE, Director of the Pharmacology-Toxicology Program at the National Insti tutes of Health, whose support made possible much of the work described in this volume. Contents Section One: Routes of Drug Administration Chapter 1: Biological Membranes and Their Passage by Drugs. C. A. M. HOGBEN 1 References. . . . . . . . . . . . . . . . . . . . . . . . . . 8 Chapter 2: Absorption of Drugs from the Gastrointestinal Tract. L. S. SCHANKER. With 5 Figures. 9 I. Introduction. . . . . . . . . . . . . . . . . . . . . . . 9 II. Methods of Study. . . . . . . . . . . . . . . . . . . . . 9 III. Absorption from the Stomach . . . . . . . . . . . . . . . 11 IV. Intestinal Absorption of Non-Electrolytes and Weak Electrolytes 15 V. Absorption of Weak Electrolytes from the Colon and Rectum 18 VI. Intestinal Absorption of Organic Ions. . . . . . . . . . 19 VII. Intestinal Absorption of Macromolecules . . . . . . . . . . 19 VIII. Active Transport across the Intestinal Epithelium . . . . . 20 IX. Effect of EDTA on Drug Absorption from the Intestine . . . . . . .

Intracellular Transport
Intracellular Transport

Author: Katherine Brehme Warren

Publisher: Academic Press

Published: 2014-05-12

Total Pages: 344

ISBN-13: 1483223752

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Intracellular Transport is a collection of papers that examines the processes of and the mechanisms underlying intracellular transport. One paper describes that all active transport processes in the amoeba are intracellular and depend on dynamic transformations of membrane into cytoplasm, and of cytoplasm into membrane. Another paper discusses the kinetics of membrane transport, of which the phenomena of counterflow can become a "mobile carrier" system. The paper notes that the specific transport properties of membranes are conferred by the proteins of the surfaces that are grouped as macromolecular complexes, probably similar to those of enzymes. One paper describes the concept of parametric pumping, an oscillation-driven separation process, as a possible model for active transport in biological cells. Another paper compares the fine-scale diffusion effects that happen in a mixture without large-scale concentration gradients and where the effect are on a large scale. The homogenous kinetic law can be used in the large-scale situation; the law already can account for any of the fine-scale diffusion effects. The paper notes that without large-scale concentration gradients, the transport event is from a local region to a nearby reaction site only. Where the effects are on a large scale, the diffusion results in a gross transport of over distances larger than molecular dimensions. This collection can prove useful for mathematicians, cellular biologists, physical chemists, physiologists, electron microscopicists, geneticists, and engineers.